Emerging Application of Nanorobotics and Artificial Intelligence To Cross the BBB: Advances in Design, Controlled Maneuvering, and Targeting of the Barriers DOI Creative Commons
Ajay Vikram Singh,

Vaisali Chandrasekar,

Poonam Janapareddy

et al.

ACS Chemical Neuroscience, Journal Year: 2021, Volume and Issue: 12(11), P. 1835 - 1853

Published: May 19, 2021

The blood–brain barrier (BBB) is a prime focus for clinicians to maintain the homeostatic function in health and deliver theranostics brain cancer number of neurological diseases. structural hierarchy situ biochemical signaling BBB neurovascular unit have been primary targets recapitulate into vitro modules. microengineered perfusion systems development 3D cellular organoid culture given major thrust research neuropharmacology. In this review, we on revisiting nanoparticles based bimolecular engineering enable them maneuver, control, target, theranostic payloads across as nanorobots or nanobots. Subsequently provide brief outline specific case studies addressing payload delivery tumor disorders (e.g., Alzheimer's disease, Parkinson's multiple sclerosis, etc.). addition, also address opportunities challenges nanorobots' design. Finally, how computationally powered machine learning (ML) tools artificial intelligence (AI) can be partnered with robotics predict design next generation interact without causing damage, toxicity, malfunctions. content review could references multidisciplinary science clinicians, roboticists, chemists, bioengineers involved cutting-edge pharmaceutical research.

Language: Английский

Advanced materials for micro/nanorobotics DOI Creative Commons
Jeonghyo Kim, Paula Mayorga Burrezo, Su-Jin Song

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(18), P. 9190 - 9253

Published: Jan. 1, 2024

Autonomous micro/nanorobots capable of performing programmed missions are at the forefront next-generation micromachinery. These small robotic systems predominantly constructed using functional components sourced from micro- and nanoscale materials; therefore, combining them with various advanced materials represents a pivotal direction toward achieving higher level intelligence multifunctionality. This review provides comprehensive overview for innovative micro/nanorobotics, focusing on five families that have witnessed most rapid advancements over last decade: two-dimensional materials, metal-organic frameworks, semiconductors, polymers, biological cells. Their unique physicochemical, mechanical, optical, properties been integrated into to achieve greater maneuverability, programmability, intelligence, multifunctionality in collective behaviors. The design fabrication methods hybrid discussed based material categories. In addition, their promising potential powering motion and/or (multi-)functionality is described fundamental principles underlying explained. Finally, extensive use variety applications, including environmental remediation, (bio)sensing, therapeutics,

Language: Английский

Citations

17

A Survey of Recent Developments in Magnetic Microrobots for Micro-/Nano-Manipulation DOI Creative Commons
Ruomeng Xu, Qingsong Xu

Micromachines, Journal Year: 2024, Volume and Issue: 15(4), P. 468 - 468

Published: March 29, 2024

Magnetically actuated microrobots have become a research hotspot in recent years due to their tiny size, untethered control, and rapid response capability. Moreover, an increasing number of researchers are applying them for micro-/nano-manipulation the biomedical field. This survey provides comprehensive overview developments magnetic microrobots, focusing on materials, propulsion mechanisms, design strategies, fabrication techniques, diverse applications. The exploration biosafety considerations, methods serves as foundation designs discussed this review. paper delves into categories, encompassing helical, surface, ciliary, scaffold, biohybrid with each demonstrating unique capabilities. Furthermore, various including direct laser writing, glancing angle deposition, biotemplating synthesis, template-assisted electrochemical self-assembly, examined owing contributions realization microrobots. potential impact across multidisciplinary domains is presented through application areas, such drug delivery, minimally invasive surgery, cell manipulation, environmental remediation. review highlights summary current challenges, hurdles overcome, future directions microrobot different fields.

Language: Английский

Citations

16

Internet of Robotic Things: Current Technologies, Challenges, Applications, and Future Research Topics DOI Creative Commons
Jakub Krejčí, Marek Babiuch, Jiří Suder

et al.

Sensors, Journal Year: 2025, Volume and Issue: 25(3), P. 765 - 765

Published: Jan. 27, 2025

This article focuses on the integration of Internet Things (IoT) and Robotic Things, representing a dynamic research area with significant potential for industrial applications. The (IoRT) integrates IoT technologies into robotic systems, enhancing their efficiency autonomy. provides an overview used in IoRT, including hardware components, communication technologies, cloud services. It also explores IoRT applications industries such as healthcare, agriculture, more. discusses challenges future directions, data security, energy efficiency, ethical issues. goal is to raise awareness importance demonstrate how this technology can bring benefits across various sectors.

Language: Английский

Citations

2

Metareview: a survey of active matter reviews DOI Creative Commons
Michael te Vrugt, Raphael Wittkowski

The European Physical Journal E, Journal Year: 2025, Volume and Issue: 48(2)

Published: Feb. 1, 2025

In the past years, amount of research on active matter has grown extremely rapidly, a fact that is reflected in particular by existence more than 1000 reviews this topic. Moreover, field become very diverse, ranging from theoretical studies statistical mechanics particles to applied work medical applications microrobots and biological systems artificial swimmers. This makes it difficult get an overview over as whole. Here, we provide such form metareview article surveys existing review articles books matter. Thereby, provides useful starting point for finding literature about specific

Language: Английский

Citations

2

Emerging Application of Nanorobotics and Artificial Intelligence To Cross the BBB: Advances in Design, Controlled Maneuvering, and Targeting of the Barriers DOI Creative Commons
Ajay Vikram Singh,

Vaisali Chandrasekar,

Poonam Janapareddy

et al.

ACS Chemical Neuroscience, Journal Year: 2021, Volume and Issue: 12(11), P. 1835 - 1853

Published: May 19, 2021

The blood–brain barrier (BBB) is a prime focus for clinicians to maintain the homeostatic function in health and deliver theranostics brain cancer number of neurological diseases. structural hierarchy situ biochemical signaling BBB neurovascular unit have been primary targets recapitulate into vitro modules. microengineered perfusion systems development 3D cellular organoid culture given major thrust research neuropharmacology. In this review, we on revisiting nanoparticles based bimolecular engineering enable them maneuver, control, target, theranostic payloads across as nanorobots or nanobots. Subsequently provide brief outline specific case studies addressing payload delivery tumor disorders (e.g., Alzheimer's disease, Parkinson's multiple sclerosis, etc.). addition, also address opportunities challenges nanorobots' design. Finally, how computationally powered machine learning (ML) tools artificial intelligence (AI) can be partnered with robotics predict design next generation interact without causing damage, toxicity, malfunctions. content review could references multidisciplinary science clinicians, roboticists, chemists, bioengineers involved cutting-edge pharmaceutical research.

Language: Английский

Citations

101