Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153653 - 153653
Published: July 1, 2024
Language: Английский
ACS Nano, Journal Year: 2023, Volume and Issue: 17(15), P. 14347 - 14405
Published: July 24, 2023
Light has profoundly impacted modern medicine and healthcare, with numerous luminescent agents imaging techniques currently being used to assess health treat diseases. As an emerging concept in luminescence, aggregation-induced emission (AIE) shown great potential biological applications due its advantages terms of brightness, biocompatibility, photostability, positive correlation concentration. This review provides a comprehensive summary AIE luminogens applied structure dynamic physiological processes, disease diagnosis treatment, detection monitoring specific analytes, followed by representative works. Discussions on critical issues perspectives future directions are also included. aims stimulate the interest researchers from different fields, including chemistry, biology, materials science, medicine, etc., thus promoting development fields life health.
Language: Английский
Citations
198
Trends in Chemistry, Journal Year: 2022, Volume and Issue: 5(1), P. 76 - 87
Published: Nov. 10, 2022
Language: Английский
Citations
165
Advanced Science, Journal Year: 2023, Volume and Issue: 10(7)
Published: Jan. 3, 2023
Carbon dots (CDs) with excellent cytocompatibility, tunable optical properties, and simple synthesis routes are highly desirable for use in bioimaging. However, the majority of existing CDs triggered by ultraviolet/blue light, presenting emissions visible/first near-infrared (NIR-I) regions, which do not allow deep tissue penetration. Emerging research into NIR-II emission red region has generated limited designs poor quantum yield, restricting their vivo imaging applications due to low penetration depth. Developing novel high yield significant far-reaching bioimaging photodynamic therapy. Here, it is developed first time Fe-doped (Fe-CDs) exhibiting linear relationship between 900-1200 nm fluorescence-emission pH values, (QY-1.27%), can be used as effective probes These findings demonstrate reliable accuracy 4 mm, reflecting real-time changes comparable a standard electrode. As an important example application, Fe-CDs probe non-invasively monitor gastric during digestion process mice, illustrating its potential aiding imaging-guided diagnosis diseases or therapeutic delivery.
Language: Английский
Citations
96
ACS Sensors, Journal Year: 2023, Volume and Issue: 8(2), P. 884 - 892
Published: Jan. 19, 2023
The development of an instrument-free, on-site, real-time, sensitive, and visualized fluoride-ion (F–) content rapid detection strategy is crucial to ensuring the health population. Smart microdevices that are portable, directly read, easy operate have recently attracted much attention. Herein, a ratiometric fluorescent probe (AA-CDs@[Ru(bpy)3]2+)-based smartphone sensing platform was developed for F–. red ruthenium bipyridine [Ru(bpy)3]2+ molecule chosen as reference signal, carbon dots (AA-CDs) with Al3+ aggregation-induced enhanced emission (AIE) were designed response signal. fluorescence changed continuously from cyan in different concentrations F–, red–green–blue (RGB) channel values image extracted through color recognition application (APP). There linear relationship between blue–red (B/R) ratio F– concentration, limit (LOD) 1.53 μM, far below allowable drinking water prescribed by World Health Organization. rapidly detected on-site satisfactory repeatability relative standard deviation using several toothpaste samples real sample. features low cost, portability, operation, good stability, selectivity, repeatability, which provides powerful tool visual quantitative smartphone-based microsensing platforms possibly fields environmental protection, diagnosis, food safety assessment.
Language: Английский
Citations
59
Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 462, P. 142339 - 142339
Published: March 9, 2023
Language: Английский
Citations
55
Carbon, Journal Year: 2024, Volume and Issue: 219, P. 118838 - 118838
Published: Jan. 17, 2024
Language: Английский
Citations
35
ACS Nano, Journal Year: 2024, Volume and Issue: 18(18), P. 11560 - 11572
Published: April 29, 2024
Second near-infrared (NIR-II) carbon dots, with absorption or emission between 1000 and 1700 nm, are gaining increasing attention in the biomaterial field due to their distinctive properties, which include straightforward preparation processes, stable photophysical characteristics, excellent biocompatibility, low cost. As a result, there is growing focus on controlled synthesis modulation of photochemical properties NIR-II aim further expand biomedical applications, current research hotspot. This account aims provide comprehensive overview recent advancements dots within field. The review will cover following topics: (i) design, synthesis, purification (ii) surface modification strategies, (iii) particularly domain cancer theranostics. Additionally, this addresses challenges encountered by outline future directions realm By exploring carbon-based biomaterials, we can anticipate that contribution garner increased contribute development next-generation advanced functional thereby offering enhanced tools strategies
Language: Английский
Citations
22
Advanced Science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 22, 2025
Abstract Repair of infectious bone defects remains a serious problem in clinical practice owing to the high risk infection and excessive reactive oxygen species (ROS) during early stage, residual bacteria delayed Osseo integrated interface later which jointly creates complex dynamic microenvironment leads non‐union. The melatonin carbon dots (MCDs) possess antibacterial osteogenesis abilities, greatly simplifying composition multifunctional material. Therefore, hydrogel containing MCDs (GH‐MCD) is developed meet multi‐stage repair needs injury this study. GH‐MCD can intelligently release responding acidic scavenge intracellular ROS exhibit good activity by inducing production inhibiting expression secA2 . Moreover, it has long‐lasting antimicrobial repair. RNA‐seq results reveal that hydrogels promote infected healing enhancing cellular resistance bacteria, balancing osteoclastogenesis, regulating immune microenvironment. In conclusion, through programmed transformation microenvironment, providing novel strategy for defects.
Language: Английский
Citations
4
Carbon, Journal Year: 2025, Volume and Issue: unknown, P. 120122 - 120122
Published: Feb. 1, 2025
Language: Английский
Citations
2
Advanced Science, Journal Year: 2022, Volume and Issue: 9(30)
Published: Sept. 1, 2022
Abstract Carbon dots (CDs) or carbonized polymer (CPDs) are an emerging class of optical materials that have exceptional applications in optoelectronic devices, catalysis, detection, and bioimaging. Although cell studies CPDs produced impressive results, vivo imaging requires available to fluoresce the near‐infrared‐II (NIR‐II) window (1000−1700 nm). Here, a two‐step bottom‐up strategy is developed synthesize NIR‐CPDs provide bright emissions both NIR‐I NIR‐II transparent windows. The designed includes hydrothermal reaction form stable carbon core with aldehyde groups, followed by Knoevenagel tether molecular emission centers. This procedure labor‐saving, cost‐efficient, produces high yield. enable high‐performance angiography real‐time disease degree colitis noninvasively. technology may therefore next‐generation synthesis for rational engineering can accurately tune absorption/emission properties NIR‐emissive CPDs.
Language: Английский
Citations
62