Biodegradable quaternized silk fibroin sponge with highly uniform pore structure for traumatic hemostasis and anti-infection DOI
Xinchen Du,

Ruxiang Li,

Tongxing Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 132989 - 132989

Published: June 7, 2024

Language: Английский

Chitosan based cryogel loaded with zeolitic imidazolate framework-67 and glucose oxidase enabling hemostasis and diabetic wound healing DOI
Nannan Zhang,

Hongkai Tian,

Wenyi Zong

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123709 - 123709

Published: May 1, 2025

Language: Английский

Citations

0
Super-expandable dual-crosslinking all-cellulose sponge: a physical and chemical solution for hemostasis in severe hemorrhage DOI Creative Commons

Xinsen Lin,

Siqi Zhang, Weijie Jiang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143837 - 143837

Published: May 1, 2025

Language: Английский

Citations

0
A 3D‐Printed Cuttlefish Bone Elastomeric Sponge Rapidly Controlling Noncompressible Hemorrhage DOI
Xinchi Zhang,

Xuqiao Wang,

Pingping Yuan

et al.

Small, Journal Year: 2023, Volume and Issue: 20(19)

Published: Dec. 10, 2023

Abstract Developing a self‐expanding hemostatic sponge with high blood absorption and rapid shape recovery for noncompressible hemorrhage remains challenge. In this study, 3D‐printed cuttlefish bone elastomeric (CBES) is fabricated, which combined ordered channels porous structures, presented tunable mechanical strength, memory potentials. The incorporation of powder (CBp) plays key roles in concentrating components, promoting aggregation red cells platelets, activating makes CBES show enhanced performance compared commercial gelatin sponges vivo. Moreover, promotes more histiocytic infiltration neovascularization the early stage degradation than sponges, conducive to regeneration repair injured tissue. To conclude, CBp loaded can promote coagulation, present potential guide tissue healing, broaden application traditional Chinese medicine.

Language: Английский

Citations

8
A macroporous composite sponge with high water absorbency and active coagulation mechanism for traumatic hemostasis and anti-infection DOI
Xinchen Du, Tongxing Zhang,

Tong Li

et al.

Biomedical Materials, Journal Year: 2024, Volume and Issue: 19(4), P. 045021 - 045021

Published: May 30, 2024

The development of a composite sponge with high water absorbency and active coagulation mechanism for traumatic hemostasis anti-infection remains challenge. Herein, we developed using gelation, swelling, freeze-drying methods based on quaternized chitosan, succinimidyl-modified F127, bioactive glass. exhibited macroporous structure, porosity, absorbency. When exposed to blood, it strongly interacted blood cells, promoting their adhesion, aggregation, activation. Moreover, activated the intrinsic pathway. sponge/powder demonstrated superior hemostatic capacity commercial gauze, gelatin sponge, Yunnan Baiyao, chitosan powder in rat tail amputation, liver superficial injury, resection, semi-perforation wound models. also presented robust activity against methicillin-resistant

Language: Английский

Citations

2
Biodegradable quaternized silk fibroin sponge with highly uniform pore structure for traumatic hemostasis and anti-infection DOI
Xinchen Du,

Ruxiang Li,

Tongxing Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 132989 - 132989

Published: June 7, 2024

Language: Английский

Citations

2