Advanced Science,
Journal Year:
2023,
Volume and Issue:
10(28)
Published: Aug. 6, 2023
Hydrogels
with
tailor-made
swelling-shrinkable
properties
have
aroused
considerable
interest
in
numerous
biomedical
domains.
For
example,
as
swelling
is
a
key
issue
for
blood
and
wound
extrudates
absorption,
the
transference
of
nutrients
metabolites,
well
drug
diffusion
release,
hydrogels
high
capacity
been
widely
applicated
full-thickness
skin
healing
tissue
regeneration,
delivery.
Nevertheless,
fields
adhesives
internal
soft-tissue
healing,
bioelectronics,
non-swelling
play
very
important
functions
owing
to
their
stable
macroscopic
dimension
physical
performance
physiological
environment.
Moreover,
negative
behavior
(i.e.,
shrinkage)
can
be
exploited
drive
noninvasive
closure,
achieve
resolution
enhancement
hydrogel
scaffolds.
In
addition,
it
help
push
out
entrapped
drugs,
thus
promote
release.
However,
there
still
has
not
general
review
constructions
applications
from
viewpoint
properties.
Therefore,
this
summarizes
tactics
employed
so
far
tailoring
applications.
And
relatively
comprehensive
understanding
current
progress
future
challenge
different
features
provided
potential
clinical
translations.
Gels,
Journal Year:
2024,
Volume and Issue:
10(4), P. 262 - 262
Published: April 13, 2024
Hydrogels,
with
their
distinctive
three-dimensional
networks
of
hydrophilic
polymers,
drive
innovations
across
various
biomedical
applications.
The
ability
hydrogels
to
absorb
and
retain
significant
volumes
water,
coupled
structural
integrity
responsiveness
environmental
stimuli,
renders
them
ideal
for
drug
delivery,
tissue
engineering,
wound
healing.
This
review
delves
into
the
classification
based
on
cross-linking
methods,
providing
insights
synthesis,
properties,
We
further
discuss
recent
advancements
in
hydrogel-based
delivery
systems,
including
oral,
injectable,
topical,
ocular
approaches,
highlighting
significance
enhancing
therapeutic
outcomes.
Additionally,
we
address
challenges
faced
clinical
translation
propose
future
directions
leveraging
potential
personalized
medicine
regenerative
healthcare
solutions.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(18)
Published: April 9, 2024
Spinal
cord
injury
(SCI)
often
leads
to
a
severe
permanent
disability.
A
poor
inflammatory
microenvironment
and
nerve
electric
signal
conduction
block
are
the
main
reasons
for
difficulty
in
spinal
regeneration.
In
this
study,
black
phosphorus
(BP)
glycyrrhizic
acid
(GA)
integrated
into
methacrylate-modified
silk
fibroin
(SF)
construct
bifunctional
injectable
hydrogel
(SF/BP/GA)
with
appropriate
conductivity
ability
inhibit
inflammation
promote
neuronal
regeneration
after
SCI.
This
work
discovers
that
SF/BP/GA
can
reduce
oxidative
damage
mediated
by
oxygen
free
radicals,
polarization
of
macrophages
toward
anti-inflammatory
M2
phenotype,
expression
factors,
improve
microenvironment.
Moreover,
it
induces
neural
stem
cell
(NSC)
differentiation
neurosphere
formation,
restores
at
SCI
site
vivo,
ameliorates
motor
function
mice
hemisection,
revealing
significant
repair
effect.
An
injectable,
electroconductive,
free-radical-scavenging
is
promising
therapeutic
strategy
repair.
Advanced Engineering Materials,
Journal Year:
2024,
Volume and Issue:
26(21)
Published: Aug. 29, 2024
The
continuous
development
of
ionizing
radiation
in
medical
imaging
and
treatment,
nuclear
reactors,
food
irradiation,
other
fields
is
accompanied
by
potential
risks.
It
protects
related
equipment
personnel
adopting
shielding
materials
to
reduce
irradiation.
Due
the
advancement
science
technology,
many
high‐performance
protection
have
been
reported.
Ionizing
a
complex
environment
involving
X‐ray
imaging,
therapy,
power
operation,
space
radiation.
Irradiation
energy,
irradiation
type,
measurement
material
essential
effects
on
efficiency.
However,
there
has
not
general
review
preparations
properties
light
different
matrixes
recent
years.
Herein,
comprehensive
overview
advancements
materials,
categorized
into
alloys,
concretes,
glasses
ceramics,
polymer
composites,
presented.
Furthermore,
synthesis
methods
employed
for
these
their
respective
are
discussed.
Finally,
current
research
gap
possible
future
scope
proposed.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(32), P. 20817 - 20826
Published: Aug. 5, 2024
The
rise
of
soft
robotics
in
recent
years
has
motivated
significant
developments
smart
materials
(and
vice
versa),
as
these
allow
for
more
compact
robotic
designs
thanks
to
the
embodied
intelligence
that
they
provide.
Hydrogels
have
long
been
postulated
one
potential
candidates
be
used
due
their
softness,
elasticity,
and
properties
can
tuned
with
nanomaterials.
However,
nowadays
represent
only
a
small
percentage
field.
In
this
perspective,
drawbacks
hindered
utilization
so
far
are
analyzed
well
current
state
hydrogel-based
actuators,
sensors,
manufacturing
possibilities.
future
improvements
need
made
achieve
real
application
hydrogels
also
discussed.
Theranostics,
Journal Year:
2025,
Volume and Issue:
15(5), P. 1689 - 1714
Published: Jan. 2, 2025
In
recent
years,
nano-drug
delivery
systems
(Nano-DDS)
that
target
the
tumor
microenvironment
(TME)
to
overcome
multidrug
resistance
(MDR)
have
become
a
research
hotspot
in
field
of
cancer
therapy.
By
precisely
targeting
TME
and
regulating
its
unique
pathological
features,
such
as
hypoxia,
weakly
acidic
pH,
abnormally
expressed
proteins,
etc.,
these
Nano-DDS
enable
effective
therapeutic
agents
reversal
MDR.
This
scientific
community
is
increasing
investment
development
diversified
exploring
their
anti-drug
potential.
Therefore,
it
particularly
important
conduct
comprehensive
review
progress
TME-targeted
years.
After
brief
introduction
MDR,
design
principle
structure
liposomes,
polymer
micelles
inorganic
nanocarriers
are
focused
on,
characteristics
described.
It
also
demonstrates
how
break
through
MDR
treatment
various
mechanisms,
discusses
synthetic
innovation,
results
overcoming
mechanisms.
The
was
concluded
with
deliberations
on
key
challenges
future
outlooks
