Advanced Science,
Journal Year:
2023,
Volume and Issue:
10(28)
Published: Aug. 6, 2023
Hydrogels
with
tailor-made
swelling-shrinkable
properties
have
aroused
considerable
interest
in
numerous
biomedical
domains.
For
example,
as
swelling
is
a
key
issue
for
blood
and
wound
extrudates
absorption,
the
transference
of
nutrients
metabolites,
well
drug
diffusion
release,
hydrogels
high
capacity
been
widely
applicated
full-thickness
skin
healing
tissue
regeneration,
delivery.
Nevertheless,
fields
adhesives
internal
soft-tissue
healing,
bioelectronics,
non-swelling
play
very
important
functions
owing
to
their
stable
macroscopic
dimension
physical
performance
physiological
environment.
Moreover,
negative
behavior
(i.e.,
shrinkage)
can
be
exploited
drive
noninvasive
closure,
achieve
resolution
enhancement
hydrogel
scaffolds.
In
addition,
it
help
push
out
entrapped
drugs,
thus
promote
release.
However,
there
still
has
not
general
review
constructions
applications
from
viewpoint
properties.
Therefore,
this
summarizes
tactics
employed
so
far
tailoring
applications.
And
relatively
comprehensive
understanding
current
progress
future
challenge
different
features
provided
potential
clinical
translations.
Gels,
Journal Year:
2024,
Volume and Issue:
10(4), P. 262 - 262
Published: April 13, 2024
Hydrogels,
with
their
distinctive
three-dimensional
networks
of
hydrophilic
polymers,
drive
innovations
across
various
biomedical
applications.
The
ability
hydrogels
to
absorb
and
retain
significant
volumes
water,
coupled
structural
integrity
responsiveness
environmental
stimuli,
renders
them
ideal
for
drug
delivery,
tissue
engineering,
wound
healing.
This
review
delves
into
the
classification
based
on
cross-linking
methods,
providing
insights
synthesis,
properties,
We
further
discuss
recent
advancements
in
hydrogel-based
delivery
systems,
including
oral,
injectable,
topical,
ocular
approaches,
highlighting
significance
enhancing
therapeutic
outcomes.
Additionally,
we
address
challenges
faced
clinical
translation
propose
future
directions
leveraging
potential
personalized
medicine
regenerative
healthcare
solutions.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(32), P. 20817 - 20826
Published: Aug. 5, 2024
The
rise
of
soft
robotics
in
recent
years
has
motivated
significant
developments
smart
materials
(and
vice
versa),
as
these
allow
for
more
compact
robotic
designs
thanks
to
the
embodied
intelligence
that
they
provide.
Hydrogels
have
long
been
postulated
one
potential
candidates
be
used
due
their
softness,
elasticity,
and
properties
can
tuned
with
nanomaterials.
However,
nowadays
represent
only
a
small
percentage
field.
In
this
perspective,
drawbacks
hindered
utilization
so
far
are
analyzed
well
current
state
hydrogel-based
actuators,
sensors,
manufacturing
possibilities.
future
improvements
need
made
achieve
real
application
hydrogels
also
discussed.
Biomaterials Research,
Journal Year:
2025,
Volume and Issue:
29
Published: Jan. 1, 2025
The
field
of
infected
wound
management
continues
to
face
challenges,
and
traditional
methods
used
cope
with
wounds
include
debridement,
gauze
coverage,
medication,
others.
Currently,
synthetic
natural
biomaterials
are
readily
available
today,
enabling
the
creation
new
dressings
that
substantially
enhance
healing.
Considerable
attention
is
being
paid
hydrogels
based
on
materials,
which
have
good
biocompatibility
degradability
properties,
while
exhibiting
higher
similarity
extracellular
matrix
as
compared
materials.
In
this
study,
we
extracted
active
ingredients
oxidized
konjac
glucomannan
(OKGM)
fresh
egg
white
(EW)
from
2
foods,
konjac,
egg,
respectively,
formed
a
self-repairing
hydrogel
cross-linking
Schiff
base.
Subsequently,
peptide,
glycyl-l-histidyl-l-lysine-Cu
(GHK-Cu),
was
loaded,
an
all-natural
composite
dressing,
EW/OKGM@GHK-Cu
(GEK),
developed.
GEK
hydrogel,
both
antibacterial
anti-inflammatory
plays
hemostatic
role
by
adhering
tissues
promoting
neovascularization
serves
optimal
dressing
for
skin
regeneration.
Taken
together,
derived
food
sources
therefore
constitute
efficient
cost-effective
strategy
managing
healing
significant
potential
clinical
application
transformation.
Theranostics,
Journal Year:
2025,
Volume and Issue:
15(5), P. 1689 - 1714
Published: Jan. 2, 2025
In
recent
years,
nano-drug
delivery
systems
(Nano-DDS)
that
target
the
tumor
microenvironment
(TME)
to
overcome
multidrug
resistance
(MDR)
have
become
a
research
hotspot
in
field
of
cancer
therapy.
By
precisely
targeting
TME
and
regulating
its
unique
pathological
features,
such
as
hypoxia,
weakly
acidic
pH,
abnormally
expressed
proteins,
etc.,
these
Nano-DDS
enable
effective
therapeutic
agents
reversal
MDR.
This
scientific
community
is
increasing
investment
development
diversified
exploring
their
anti-drug
potential.
Therefore,
it
particularly
important
conduct
comprehensive
review
progress
TME-targeted
years.
After
brief
introduction
MDR,
design
principle
structure
liposomes,
polymer
micelles
inorganic
nanocarriers
are
focused
on,
characteristics
described.
It
also
demonstrates
how
break
through
MDR
treatment
various
mechanisms,
discusses
synthetic
innovation,
results
overcoming
mechanisms.
The
was
concluded
with
deliberations
on
key
challenges
future
outlooks
Gels,
Journal Year:
2025,
Volume and Issue:
11(1), P. 72 - 72
Published: Jan. 16, 2025
Stimulus-responsive
hydrogels
have
emerged
as
versatile
materials
for
environmental
and
wastewater
treatment
applications
due
to
their
ability
adapt
changing
conditions.
This
review
highlights
recent
advances
in
the
design,
synthesis,
functionalization
of
such
hydrogels,
focusing
on
applications.
Various
synthesis
techniques,
including
radical
polymerization,
grafting,
copolymerization,
enable
development
with
tailored
properties
enhanced
adsorption
capacity,
selectivity,
reusability.
The
incorporation
nanoparticles
bio-based
polymers
further
improves
structural
integrity
pollutant
removal
efficiency.
Key
mechanisms
adsorption,
ion
exchange,
photodegradation
are
discussed,
emphasizing
roles
removing
heavy
metals,
dyes,
organic
pollutants
from
wastewater.
Additionally,
this
presents
potential
oil-water
separation,
pathogen
control,
future
sustainability
through
integration
into
circular
economy
frameworks.
adaptability,
cost-effectiveness,
eco-friendliness
these
make
them
promising
candidates
large-scale
remediation.
