Advanced Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 24, 2024
Cuproptosis
that
utilizes
copper
ionophore
to
induce
programmed
cell
death
holds
promise
for
enhancing
the
effectiveness
of
conventional
anticancer
therapies
and
triggering
efficient
adaptive
immune
responses.
However,
non-tumor-specific
release
Cu
ions
can
cuproptosis
cause
irreversible
damage
normal
tissues.
To
maximize
therapeutic
effects
tumor-specific
cuproptosis,
this
work
reports
first
time
regulation
degradation
behaviors
Cu-based
nanomaterials
using
graphene
quantum
dots
(GQDs)
as
a
protection
layer.
The
deposition
GQDs
not
only
avoids
The
complex
microenvironment
of
persistent
inflammation
and
bacterial
infection
is
a
major
challenge
in
chronic
diabetic
wounds.
development
nanozymes
capable
efficiently
scavenging
reactive
oxygen
species
(ROS)
promising
method
to
promote
wound
healing.
However,
many
show
rather
limited
antioxidant
activity
ROS-dependent
antibacterial
effects
under
certain
circumstances,
further
weakening
their
ability
scavenge
ROS.
To
meet
these
challenges,
electronically
regulated
bioheterojunction
(E-bio-HJ)
nanozyme
hydrogels
derived
from
metal-organic
frameworks
(MOFs)
were
designed
prepared
via
an
interface
engineering
strategy.
Owing
the
electron
transfer
redistribution
abundant
highly
dispersed
Cu-O-Zn
sites
at
heterogeneous
interface,
E-bio-HJ
exhibited
catalase
(CAT)-like
with
ultrahigh
hydrogen
peroxide
affinity
(
Tooth
discoloration
and
the
breeding
of
oral
microorganisms
pose
threats
to
both
one's
aesthetic
appearance
health.
Clinical
whitening
agents
based
on
H
APL Bioengineering,
Journal Year:
2024,
Volume and Issue:
8(4)
Published: Oct. 4, 2024
Cancer
nanotechnology
is
a
promising
area
of
cross-disciplinary
research
aiming
to
develop
facile,
effective,
and
noninvasive
strategies
improve
cancer
diagnosis
treatment.
Catalytic
therapy
based
on
exogenous
stimulus-responsive
semiconductor
nanomaterials
has
shown
its
potential
address
the
challenges
under
most
global
medical
needs.
Semiconductor
nanocatalytic
usually
triggered
by
catalytic
action
hot
electrons
holes
during
local
redox
reactions
within
tumor,
which
represent
response
nontoxic
nanocatalysts
pertinent
internal
or
external
stimuli.
However,
careful
architecture
design
been
major
focus
since
efficiency
often
limited
facile
electron/hole
recombination.
Addressing
these
vital
for
progress
therapy.
In
recent
years,
diverse
have
developed,
with
heterojunctions
emerging
as
prominent
extensively
explored
method.
The
charge
separation
stimulation
can
be
heightened
manipulating
semiconducting
performance
materials
through
heterojunction
structures,
thereby
enhancing
capabilities.
This
review
summarizes
applications
nanoheterojunctions
theranostics.
first
part
outlines
construction
different
types.
next
section
designs,
properties,
mechanisms
various
in
tumor
concludes
discussing
providing
insights
into
their
prospects
this
dynamic
continuously
evolving
field
research.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 24, 2024
Cuproptosis
that
utilizes
copper
ionophore
to
induce
programmed
cell
death
holds
promise
for
enhancing
the
effectiveness
of
conventional
anticancer
therapies
and
triggering
efficient
adaptive
immune
responses.
However,
non-tumor-specific
release
Cu
ions
can
cuproptosis
cause
irreversible
damage
normal
tissues.
To
maximize
therapeutic
effects
tumor-specific
cuproptosis,
this
work
reports
first
time
regulation
degradation
behaviors
Cu-based
nanomaterials
using
graphene
quantum
dots
(GQDs)
as
a
protection
layer.
The
deposition
GQDs
not
only
avoids
