Advanced Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 4, 2024
Abstract
A
deeper
understanding
of
disease
heterogeneity
highlights
the
urgent
need
for
precision
medicine.
Microfluidics,
with
its
unique
advantages,
such
as
high
adjustability,
diverse
material
selection,
low
cost,
processing
efficiency,
and
minimal
sample
requirements,
presents
an
ideal
platform
medicine
applications.
As
nanoparticles,
both
biological
origin
therapeutic
purposes,
become
increasingly
important
in
medicine,
microfluidic
nanoparticle
separation
proves
particularly
advantageous
handling
valuable
samples
personalized
This
technology
not
only
enhances
detection,
diagnosis,
monitoring,
treatment
accuracy,
but
also
reduces
invasiveness
medical
procedures.
review
summarizes
fundamentals
techniques
starting
examination
properties
essential
core
principles
that
guide
various
methods.
It
then
explores
passive,
active,
hybrid
techniques,
detailing
their
principles,
structures,
Furthermore,
contributions
to
advancements
liquid
biopsy
nanomedicine.
Finally,
it
addresses
existing
challenges
envisions
future
development
spurred
by
emerging
technologies
advanced
materials
science,
3D
printing,
artificial
intelligence.
These
interdisciplinary
collaborations
are
anticipated
propel
platformization
significantly
expanding
potential
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(36), P. 47206 - 47215
Published: Aug. 27, 2024
Rheumatoid
arthritis
(RA)
is
a
systemic
autoimmune
disorder
that
severely
compromises
joint
health.
The
primary
therapeutic
strategy
for
advanced
RA
aims
to
inhibit
inflammation.
However,
the
nonspecific
distribution
of
pharmacological
agents
has
limited
efficacy
and
heightens
risks
associated
with
treatment.
To
address
this
issue,
we
developed
mesenchymal
stem
cell
(MSC)-based
biomimetic
liposomes,
termed
MSCsome,
which
were
composed
fusion
between
MSC
membranes
liposomes.
some
relatively
simple
preparation
method
effectively
enhanced
targeting
efficiency
drug
diseased
joints.
Interaction
lymphocyte
function-associated
antigen-1
intercellular
adhesion
molecule-1
affinity
MSCsome
polarized
macrophages,
thereby
improving
its
capability
affected
effective
targeted
delivery
facilitated
accumulation
in
joints,
resulting
significant
inhibition
inflammation,
as
well
protection
repair
cartilage.
In
conclusion,
study
introduced
promising
approach
treatment
RA,
providing
novel
perspective
on
therapy
inflammatory
diseases.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(47), P. 64410 - 64423
Published: Nov. 12, 2024
Carbon-nitride-based
(CN-based)
materials
have
shown
great
potential
in
combination
therapy
recent
years.
Due
to
their
outstanding
biocompatibility,
ease
of
modification,
and
adjustable
band-gap
position,
CN-based
can
be
applied
as
photosensitizers
photodynamic
(PDT)
light-driven
water-splitting
catalysts
gas
therapy.
After
doping
with
other
elements,
the
photocatalytic
performance
will
enhanced,
more
interesting
functions
obtained.
In
addition,
large
specific
surface
area
also
promotes
drug
carriers
combined
therapeutic
modalities
achieve
This
Review
analyzes
summarizes
latest
research
on
therapies,
such
PDT
photothermal
(PTT),
sonodynamic
(SDT),
therapy,
gene
PDT,
bioimaging-guided
particular,
applications
are
summarized
for
first
time.
Finally,
current
challenges
faced
by
further
discussed.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 4, 2024
Abstract
A
deeper
understanding
of
disease
heterogeneity
highlights
the
urgent
need
for
precision
medicine.
Microfluidics,
with
its
unique
advantages,
such
as
high
adjustability,
diverse
material
selection,
low
cost,
processing
efficiency,
and
minimal
sample
requirements,
presents
an
ideal
platform
medicine
applications.
As
nanoparticles,
both
biological
origin
therapeutic
purposes,
become
increasingly
important
in
medicine,
microfluidic
nanoparticle
separation
proves
particularly
advantageous
handling
valuable
samples
personalized
This
technology
not
only
enhances
detection,
diagnosis,
monitoring,
treatment
accuracy,
but
also
reduces
invasiveness
medical
procedures.
review
summarizes
fundamentals
techniques
starting
examination
properties
essential
core
principles
that
guide
various
methods.
It
then
explores
passive,
active,
hybrid
techniques,
detailing
their
principles,
structures,
Furthermore,
contributions
to
advancements
liquid
biopsy
nanomedicine.
Finally,
it
addresses
existing
challenges
envisions
future
development
spurred
by
emerging
technologies
advanced
materials
science,
3D
printing,
artificial
intelligence.
These
interdisciplinary
collaborations
are
anticipated
propel
platformization
significantly
expanding
potential
