Metal-free stereoselective intramolecular oxyamination of al-kynes using a robotic and rapid photocatalytic synthesis and screening system DOI
Jiamin Lu,

Yihui Mao,

Qihang Guo

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 27(3), P. 560 - 565

Published: Dec. 17, 2024

Utilizing a robotic visible-light photocatalytic system, we realized metal-free and 100% atom-economical method for the difunctionalization of alkynes with high stereoselectivity regioselectivity.

Language: Английский

Photoredox-catalyzed cascade [2+2+1] cyclization of 1,6-enynes with thiols DOI Creative Commons
Zhe Meng, Min Shi, Yin Wei

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(12), P. 3442 - 3450

Published: Jan. 1, 2024

Here, we report a visible-light-mediated [2 + 2 1] cascade cyclization of 1,6-enynes with thiols, providing sulfur-containing polycyclic molecules in moderate to good yields.

Language: Английский

Citations

0
Radical-Mediated Trifunctionalization Reactions DOI Creative Commons
Qiang Zhang, Xiaoming Ma, Sanjun Zhi

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3620 - 3620

Published: July 31, 2024

Synthetic radicals have intrinsic power for cascading and multifunctional reactions to construct diverse molecular scaffolds. In the previous review series, we covered 1,2-difunctionalizations, remote 1,3-, 1,4-, 1,5-, 1,6-, 1,7-difunctionalizations, addition followed by cyclization reactions, cycloaddition-initiated difunctionalizations. Presented in this paper are radical addition-initiated trifunctionalization of alkenes, alkynes, their derivatives. After initial addition, there different pathways, such as group or hydrogen atom transfer, cyclization, coupling, complete second third functionalizations.

Language: Английский

Citations

0
anti-Selective Carboacylation of Alkynes via Photoredox/Nickel Dual Catalysis DOI

Xianhua Pan,

Chang-Xin Shi,

Ya-Ping Hou

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(44), P. 9498 - 9502

Published: Oct. 31, 2024

Here, we report an intermolecular carboacylation of terminal alkynes with tertiary and secondary alkyltrifluoroborates as well acyl chlorides via photoredox/nickel dual catalysis, affording a varity stereodefined trisubstituted enones in good to excellent yields E stereoselectivity, through radical relay process. This redox-neutral protocol exhibits functional group tolerance, exclusive regio- broad compatibility various alkyltrifluoroborates.

Language: Английский

Citations

0
Selective 1,2‐Carboimination of Isothiocyanates to Access S‐Substituted Isothioureas via Energy Transfer Catalysis DOI

Li‐Ning Chen,

S. K. Liang,

Juan Luo

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract Herein, we introduce a novel method for the synthesis of S ‐substituted isothiourea compounds via selective 1,2‐carboimination between oxime esters as bifunctional reagents and C=S bond isothiocyanates under visible‐light catalysis. This approach deviates from conventional methods by precisely modulating substrate electronics to selectively functionalize over C=N bond, eliminating need strong bases high temperatures bypassing formation thiourea intermediates. Consequently, this protocol enables efficient one‐step ‐alkyl isothioureas, with featuring mild reaction conditions, operational simplicity broad scope.

Language: Английский

Citations

0
Metal-free stereoselective intramolecular oxyamination of al-kynes using a robotic and rapid photocatalytic synthesis and screening system DOI
Jiamin Lu,

Yihui Mao,

Qihang Guo

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 27(3), P. 560 - 565

Published: Dec. 17, 2024

Utilizing a robotic visible-light photocatalytic system, we realized metal-free and 100% atom-economical method for the difunctionalization of alkynes with high stereoselectivity regioselectivity.

Language: Английский

Citations

0