Molecules,
Journal Year:
2024,
Volume and Issue:
30(1), P. 105 - 105
Published: Dec. 30, 2024
Surface-enhanced
Raman
scattering
(SERS)
stands
out
as
a
highly
effective
molecular
identification
technique,
renowned
for
its
exceptional
sensitivity,
specificity,
and
non-destructive
nature.
It
has
become
main
technology
in
various
sectors,
including
biological
detection
imaging,
environmental
monitoring,
food
safety.
With
the
development
of
material
science
expansion
application
fields,
SERS
substrate
materials
have
also
undergone
significant
changes:
from
precious
metals
to
semiconductors,
single
crystals
composite
particles,
rigid
flexible
substrates,
two-dimensional
three-dimensional
structures.
This
report
delves
into
advancements
three
latest
types
substrates:
colloidal,
chip-based,
tip-enhanced
spectroscopy.
explores
design
principles,
distinctive
functionalities,
factors
that
influence
signal
enhancement
within
SERS-active
nanomaterials.
Furthermore,
it
provides
an
outlook
on
future
challenges
trends
field.
The
insights
presented
are
expected
aid
researchers
fabrication
substrates
not
only
more
efficient
but
cost-effective.
progress
is
crucial
multifunctionalization
their
successful
implementation
real-world
applications.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(30)
Published: June 13, 2024
Volatile
Organic
Compounds
(VOC)
are
a
major
class
of
environmental
pollutants
hazardous
to
human
health,
but
also
highly
relevant
in
other
fields
including
early
disease
diagnostics
and
organoleptic
perception
aliments.
Therefore,
accurate
analysis
VOC
is
essential,
need
for
new
analytical
methods
witnessed
rapid
on-site
detection
without
complex
sample
preparation.
Surface-Enhanced
Raman
Spectroscopy
(SERS)
offers
rapidly
developing
versatile
platform
the
portable
chemical
species.
Nonetheless,
efficient
docking
target
analytes
at
metallic
surface
significantly
narrows
applicability
SERS.
This
limitation
can
be
circumvented
by
interfacing
sensor
with
Metal-Organic
Frameworks
(MOF).
These
materials
featuring
structural
versatility
efficiently
pre-concentrate
low
molecular
weight
species
such
as
through
their
ordered
porous
structure.
review
presents
recent
trends
development
MOF-based
SERS
substrates
focus
on
elucidating
respective
design
rules
maximizing
performance.
An
overview
status
harmful
discussed
context
industrial
monitoring.
In
addition,
survey
biomarkers
medical
diagnosis
emerging
applications
aroma
flavor
profiling
included.
Discover Chemistry.,
Journal Year:
2025,
Volume and Issue:
2(1)
Published: Feb. 10, 2025
Pesticides
are
physical
or
biological
agents,
and
their
quantities
in
the
surroundings
must
be
controlled
closely
monitored
since
they
hazardous
to
people,
animals,
environment.
Although
there
traditional
methods
for
detecting
pesticides,
such
as
gas
chromatography/liquid
chromatography–mass
spectroscopy
(GC/LC–MS),
researchers
have
recently
developed
alternative
approaches
due
modern
methods'
affordability,
environmental
friendliness,
ease
of
use.
Surface-enhanced
Raman
(SERS)
relies
on
optical
properties
nanostructured
materials
significantly
amplify
signals,
enabling
sensitive
rapid
detection
pesticide
residues.
By
functionalizing
nanoparticles
(NPs)
with
specific
receptors,
these
sensors
provide
efficient
monitoring
management
through
prompt
pollution
detection.
This
review
addresses
limitations
examines
role
nanomaterials
(NMs)
enhancing
SERS-based
Further,
it
will
summarize
potential
NMs
transforming
improving
accuracy
efficiency
advances
nanostructure
design
SERS
technologies.
ACS Nano,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 27, 2025
Since
the
1980s,
surface
enhanced
Raman
scattering
(SERS)
has
been
used
for
rapid
and
sensitive
detection
of
biomolecules.
Whether
a
label-free
or
labeled
assay
is
adopted,
SERS
demonstrated
low
limits
in
variety
biological
matrices.
However,
analysis
confined
to
laboratory
due
several
reasons
such
as
reproducibility
scalability,
both
which
have
discussed
at
length
literature.
Another
possible
issue
with
lack
widespread
adoption
that
its
application
point
use
(POU)
testing
only
now
being
fully
explored
advent
portable
spectrometers.
Researchers
are
investigating
how
can
be
output
on
POU
platforms
lateral
flow
assays,
wearable
sensors,
volatile
organic
compound
(VOC)
human
healthcare
monitoring,
favorable
results
rival
gold
standard
approaches.
obstacle
faces
interpretation
wealth
information
obtained
from
platform.
To
combat
this,
machine
learning
shown
provide
quick
accurate
generated
data,
leading
discrimination
many
clinically
relevant
This
review
will
discuss
advancements
combined
strength
bring
produce
powerful
platform
monitoring.
Langmuir,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 3, 2025
Surface-enhanced
Raman
scattering
(SERS)
is
an
advantageous
method
for
organic
chemical
and
biological
sensing.
Benzoic
acid,
benzisothiazolinone,
thiram
are
common
model
compounds
used
to
study
the
interaction
of
toxic
substances
with
metal
surfaces
using
SERS
spectroscopy.
Metal-organic
frameworks,
their
high
porosity
large
surface
area,
have
recently
received
a
lot
attention
in
sensing
applications.
Plasmonic
porous
structures
promising
substrates
because
broadband
charge-transfer
resonance
reproducibility
fabrication.
Furthermore,
exceptional
enhancement
electromagnetic
field
makes
plasmonic
nanomaterials
ideal
substrates.
In
this
study,
we
developed
based
on
ZIF-8/Au
NPs
through
self-assembly
process
that
forms
stacked
layers.
The
substrate
demonstrated
remarkable
ability
enhance
scattering,
enabling
ultrasensitive
detection
various
target
molecules
at
micromolar
concentrations.
These
attributes
establish
it
as
biosensing
