Macrophage biomimetic intelligent hollow MnO2 nanoparticle for synergistic sonodynamic-immunotherapy of glioblastoma by crossing blood brain barrier DOI Creative Commons
Jinfeng Yang,

Danyang Qu,

Hui Qiu

et al.

Materials & Design, Journal Year: 2024, Volume and Issue: unknown, P. 113483 - 113483

Published: Nov. 1, 2024

Language: Английский

Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit “ferroptosis storm” and modulate immune targeting for acute kidney injury DOI
Yuxin Cao, Xiaowei Liu,

Chunjing Guo

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 379, P. 59 - 76

Published: Jan. 8, 2025

Language: Английский

Citations

5
Engineered Macrophage Membrane-Coated Nanoparticles Attenuate Calcium Oxalate Nephrocalcinosis-Induced Kidney Injury by Reducing Oxidative Stress and Pyroptosis DOI

Xiaozhuo Ba,

Tao Ye,

Yu He

et al.

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

1
Irisin‐Encapsulated Mitochondria‐Targeted Biomimetic Nanotherapeutics for Alleviating Acute Kidney Injury DOI Creative Commons
Xia Zhang, Lijia Liang,

Fengxian Wang

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: 11(38)

Published: Aug. 9, 2024

Acute kidney injury (AKI) is the sudden decrease in renal function that can be attributed to dysregulated reactive oxygen species (ROS) production and impaired mitochondrial function. Irisin, a type I membrane protein secreted by skeletal muscles response physical activity, has been reported alleviate damage through regulation of biogenesis oxidative metabolism. In this study, macrophage membrane-coated metal-organic framework (MCM@MOF) developed as nanocarrier for encapsulating irisin overcome inherent characteristics irisin, including short circulation time, limited kidney-targeting ability, low permeability. The engineered irisin-mediated biomimetic nanotherapeutics have extended time enhanced targeting capability toward injured kidneys due preservation proteins. irisin-encapsulated effectively mitigate acute ischemia-reperfusion protecting modulating SOD2 levels tubular epithelial cells. present study provides novel insights advance development potential therapeutic approach AKI.

Language: Английский

Citations

8
Harnessing the power of nanoagents in acute kidney injury: A versatile platform for imaging and treatment DOI
Peng Liu, Yu Zhao, Ying Peng

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 533, P. 216570 - 216570

Published: Feb. 27, 2025

Language: Английский

Citations

0
Renal-Clearable and Mitochondria-Targeted Metal-Engineered Carbon Dot Nanozymes for Regulating Mitochondrial Oxidative Stress in Acute Kidney Injury DOI Creative Commons

Jiangpeng Pan,

Juntao Wang, Wei Wang

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: unknown, P. 101717 - 101717

Published: March 1, 2025

Language: Английский

Citations

0
MOF and COF platforms toward kidney-disease: Advanced nanovehicles for effective diagnosing and treatment DOI
Yamei Yu,

Abdulnasser Mahmoud Karami,

Lin Yuan

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113534 - 113534

Published: April 1, 2025

Language: Английский

Citations

0
Irisin Is a Potential Novel Biomarker and Therapeutic Target Against Kidney Diseases DOI

Xiu Huang,

Xiya Ren,

Limei Zhao

et al.

Cell Biochemistry and Function, Journal Year: 2025, Volume and Issue: 43(5)

Published: May 1, 2025

ABSTRACT Kidney diseases, characterized by renal dysfunction, are the leading causes of death worldwide. It is crucial to prevent and treat kidney diseases reduce their associated morbidity mortality. Moderate physical exercise has been recognized be advantageous for health. Irisin an exercise‐induced myokine that was identified in 2012. plays important role energy bone metabolism, oxidative stress reduction, anti‐inflammatory processes, cell inhibition, cardiovascular protection. However, relationship between irisin have not fully elucidated. This review explores as a biomarker disease diagnosis its complications, well mechanisms through which it participates various pathways, such apoptosis, autophagy, pyroptosis, ferroptosis. Furthermore, secretion levels were discussed provide basis prevention treatment avenues, therapeutic guidance developing new promising intervention strategies. Clinical Trial Registration : None.

Language: Английский

Citations

0
How Traditional Chinese Medicine Can Play a Role In Nanomedicine? A Comprehensive Review of the Literature DOI Creative Commons
Chi Wang,

K. J. Ren,

Mei Yang

et al.

International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 6289 - 6315

Published: May 1, 2025

Language: Английский

Citations

0
Macrophage biomimetic intelligent hollow MnO2 nanoparticle for synergistic sonodynamic-immunotherapy of glioblastoma by crossing blood brain barrier DOI Creative Commons
Jinfeng Yang,

Danyang Qu,

Hui Qiu

et al.

Materials & Design, Journal Year: 2024, Volume and Issue: unknown, P. 113483 - 113483

Published: Nov. 1, 2024

Language: Английский

Citations

1