Magnetic Polymeric Conduits in Biomedical Applications

Micromachines, Journal Year: 2025, Volume and Issue: 16(2), P. 174 - 174

Published: Jan. 31, 2025

Magnetic polymeric conduits are developing as revolutionary materials in regenerative medicine, providing exceptional benefits directing tissue healing, improving targeted medication administration, and facilitating remote control via external magnetic fields. The present article offers a thorough examination of current progress the design, construction, functionalization these hybrid systems. integration nanoparticles into matrices confers distinctive features, including regulated alignment, improved cellular motility, medicinal delivery, while preserving structural integrity. Moreover, incorporation multifunctional attributes, such electrical conductivity for cerebral stimulation optical characteristics real-time imaging, expands their range applications. Essential studies indicate that dimensions, morphology, surface chemistry, composition significantly affect biocompatibility, degrading characteristics, overall efficacy. Notwithstanding considerable advancements, issues concerning long-term biodegradability, scalability persist, addition to must uniform regulatory frameworks facilitate clinical translation. Progress additive manufacturing nanotechnology is overcoming obstacles, creation dynamic adaptive conduit structures designed particular biomedical requirements. conduits, by integrating usefulness safety, set transform therapies, presenting new avenue customized medicine advanced healthcare solutions.

Language: Английский

Magnetically Guided Microcatheter for Targeted Injection of Magnetic Particle Swarms

Advanced Science, Journal Year: 2024, Volume and Issue: 11(38)

Published: Aug. 9, 2024

The initial delivery of small-scale magnetic devices such as microrobots is a key, but often overlooked, aspect for their use in clinical applications. deployment these within the dynamic environment human body presents significant challenges due to dispersion caused by circulatory flows. Here, method introduced effectively deliver swarm nanoparticles fluidic This approach integrates magnetically navigated robotic microcatheter equipped with reservoir storing nanoparticles. microfluidic flow facilitates injection into fluid stream, and field gradient guides through oscillatory target site. are engineered enable steering To demonstrate this approach, experiments conducted utilizing spinal cord phantom simulating intrathecal catheter applications central nervous system. These results that proposed successfully concentrates near desired location precise manipulation gradients, offering promising solution controlled untethered micro-/nanodevices complex physiological systems body.

Language: Английский