Wnt-Regulated Therapeutics for Blood-Brain Barrier Modulation and Cancer Therapy DOI
Pei An, Yang Tong, Rui Mu

et al.

Bioconjugate Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

The Wnt signaling pathway has a significant regulatory part in tissue development and homeostasis. Dysregulation of the been associated with many diseases including cancers various brain diseases, making this promising therapeutic target for these diseases. In review, we describe roles blood-brain barrier (BBB) intracranial tumors peripheral tumors, from preclinical clinical perspectives, introduce Wnt-regulated therapeutics types drugs nanomedicines as BBB modulators brain-oriented drug delivery cancer treatments, finally discuss limitations future perspectives therapeutics.

Language: Английский

Wnt-Regulated Therapeutics for Blood-Brain Barrier Modulation and Cancer Therapy DOI
Pei An, Yang Tong, Rui Mu

et al.

Bioconjugate Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

The Wnt signaling pathway has a significant regulatory part in tissue development and homeostasis. Dysregulation of the been associated with many diseases including cancers various brain diseases, making this promising therapeutic target for these diseases. In review, we describe roles blood-brain barrier (BBB) intracranial tumors peripheral tumors, from preclinical clinical perspectives, introduce Wnt-regulated therapeutics types drugs nanomedicines as BBB modulators brain-oriented drug delivery cancer treatments, finally discuss limitations future perspectives therapeutics.

Language: Английский

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