Zwitterionic Hydrogels: From Synthetic Design to Biomedical Applications

Langmuir, Journal Year: 2025, Volume and Issue: 41(5), P. 3007 - 3026

Published: Jan. 31, 2025

Zwitterionic hydrogels have emerged as a highly promising class of biomaterials, attracting considerable attention due to their unique properties and diverse biomedical applications. moieties, with balanced positive negative charges, endow exceptional hydration, resistance nonspecific protein adsorption, low immunogenicity distinctive molecular structure. These facilitate various applications, such medical device coatings, tissue engineering, drug delivery, biosensing. This review explores the structure-property relationships in zwitterionic hydrogels, highlighting recent advances design principles, synthesis methods, structural characteristics, To meet evolving growing demand for field, this examines current challenges future research directions optimizing multifunctional hydrogels. As candidates advanced are poised address critical paving way improved therapeutic outcomes broader applicability healthcare.

Language: Английский

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A combined numerical and theoretical study on the strengthening and toughening mechanisms of double network hydrogels

International Journal of Smart and Nano Materials, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 25

Published: March 15, 2025

Language: Английский

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Strategy to Develop Multifunctional Hydrogel Coatings with High Durability

Langmuir, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Hydrophilic gel coatings have emerged as a promising strategy for surface modification and functionalization of biomedical devices. Nevertheless, most existing suffer from significant limitations, such low adhesion strength to substrates, fragility, complex preparation process involved with toxic solvents. Herein, overcome these issues simultaneously, we proposed simple method fabricate hydrogel coating based on tetraethyl orthosilicate (TEOS) copolymer poly(2-hydroxyethyl methacrylate) segments. The solution TEOS the can be applied substrate surfaces through various techniques, including drop coating, dip brush so on. Covalent bonds formed in situ condensation reaction occurred between silanol (originated TEOS) hydroxyl groups (on polymer plasma-treated substrate), ensuring robust durability coating. Notably, by copolymerizing certain monomers, customized functions could realized, underscoring practical value strategy.

Language: Английский

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Supramolecular Zwitterionic Hydrogels for Information Encryption, Soft Electronics and Energy Storage at Icy Temperature

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Abstract Zwitterionic hydrogels have attracted intensive attentions for their exceptional hydration and anti‐fouling properties, while the exploration rational structural designs to achieve multi‐function superior anti‐freezing capability remains an ongoing mission. Herein, a new multi‐functional zwitterionic monomer (ACHPES) is designed developed from which novel are fabricated. The pyridinium‐sulfonate motif endows hydrogel with discoloration in both visible light fluorescence response pH stimulus, enabling unique multi‐channel information encryption highly sensitive Cu 2+ detection threshold of 0.64 ppm. design carbamate group fulfils high bonding capacity water, leading capability. As such, exhibit extremely low water freezing point −47.3 °C breaking elongation ≈500% at −20 °C. outstanding enables sensors electrolytes excellent operational performance temperatures. This innovative strategy offers avenue functionalization application icy temperature.

Language: Английский

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A Carbon Nanotube/Pyrrolidonecarboxylic Acid Zinc Sponge for programmed management of Diabetic Wounds: Hemostatic, Antibacterial, Anti-inflammatory, and Healing Properties

Materials Today Bio, Journal Year: 2025, Volume and Issue: unknown, P. 101769 - 101769

Published: April 1, 2025

Language: Английский

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