Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Abstract Colorectal cancer (CRC) ranks as the third most prevalent worldwide. It is associated with imbalanced gut microbiota. Probiotics can help restore this balance, potentially reducing risk of CRC. However, hostile environment and constant changes in gastrointestinal tract pose significant challenges to efficient delivery probiotics colon. Traditional methods are often insufficient due their low viability lack targeting. To address these challenges, researchers increasingly focusing on innovative encapsulation technologies. One such approach single‐cell encapsulation, which involves applying nanocoatings individual probiotic cells. This technique improve resistance harsh environment, enhance mucosal adhesion, facilitate targeted release, thereby increasing effectiveness delivery. article reviews latest developments for CRC treatment, emphasizing potential benefits emerging techniques. also analyzes compares advantages disadvantages current Furthermore, it elucidates underlying mechanisms through prevent treat CRC, evaluates efficacy safety treatment adjuvant therapy, discusses future directions prevention.

Language: Английский