Constructing Polymetallic Nodes in Metal–Organic Frameworks Enhance Antibacterial of Drug‐Resistant Bacteria DOI Creative Commons

Qinqin Li,

Shihan Zhang, Yachao Xu

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 26, 2025

Abstract The misuse of antibiotics results in the emergence a large number drug‐resistant bacteria, which leads to huge financial and social burdens. Exploring artificial nanozymes is regarded as promising candidates for substitution antibiotics, but still remain challenge. Herein, new strategy reported constructing polymetallic indium coordination node Metal‐organic frameworks (MOFs) (polyIn‐BTB) enhancing production reactive oxygen species (ROS), significantly promote antibacterial activity. Theoretical research reveals that, compared monometallic MOFs (monoIn‐BTB), polyIn‐BTB exhibits stronger electron‐donating ability, can facilitate efficient ROS. Thus, shows outstanding properties 87.0% 92.0% Methicillin‐Resistant Staphylococcus aureus ( MRS. ) Escherichia coli E. respectively, higher than that monoIn‐BTB (42% Aureus 50% ). vivo experiments demonstrate accelerates wound healing by killing bacteria inhibiting inflammatory response they cause, with rate 98.0% 8 days. Overall, this work reports performance, opens door fundamental on designing nanozyme high performance.

Language: Английский

Metal-organic frameworks-molecularly imprinted polymers (MOF-MIP): Synthesis, properties, and applications in detection and control of microorganisms DOI
Yen P. Kong, Yuhan Sun, Z. Ryan Tian

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 252, P. 114670 - 114670

Published: April 6, 2025

Language: Английский

Citations

0
Recent Advances in the Design and Biocidal Mechanisms of Room-temperature Catalytic Nanomaterials for Efficient Inactivation of Bioaerosols DOI
Wenhui Cheng, Zhenyu Wang, Shiqi Peng

et al.

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 106449 - 106449

Published: April 1, 2025

Language: Английский

Citations

0
Layered dual-metal nodes metal organic frameworks artificial nanozymes boost the production of reactive oxygen species for antibacterial of drug-resistant bacteria DOI

Qinqin Li,

F. Liu,

Shihan Zhang

et al.

Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 693, P. 137608 - 137608

Published: April 17, 2025

Language: Английский

Citations

0
Constructing Polymetallic Nodes in Metal–Organic Frameworks Enhance Antibacterial of Drug‐Resistant Bacteria DOI Creative Commons

Qinqin Li,

Shihan Zhang, Yachao Xu

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 26, 2025

Abstract The misuse of antibiotics results in the emergence a large number drug‐resistant bacteria, which leads to huge financial and social burdens. Exploring artificial nanozymes is regarded as promising candidates for substitution antibiotics, but still remain challenge. Herein, new strategy reported constructing polymetallic indium coordination node Metal‐organic frameworks (MOFs) (polyIn‐BTB) enhancing production reactive oxygen species (ROS), significantly promote antibacterial activity. Theoretical research reveals that, compared monometallic MOFs (monoIn‐BTB), polyIn‐BTB exhibits stronger electron‐donating ability, can facilitate efficient ROS. Thus, shows outstanding properties 87.0% 92.0% Methicillin‐Resistant Staphylococcus aureus ( MRS. ) Escherichia coli E. respectively, higher than that monoIn‐BTB (42% Aureus 50% ). vivo experiments demonstrate accelerates wound healing by killing bacteria inhibiting inflammatory response they cause, with rate 98.0% 8 days. Overall, this work reports performance, opens door fundamental on designing nanozyme high performance.

Language: Английский

Citations

0