High-Entropy Alloy/Zinc Sulfide Heterojunction-Based Hydrogel for Eliminating Bacteria and Stimulating Osteoblast Response DOI

Young-Fa Lin,

Qin Zhang,

Shangyu Xie

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Integration of a high-entropy alloy (HEA) with nanozyme activity and piezoelectric material piezoelectricity is promising strategy to develop novel biofunctional for the repair infectious bone defects. Herein, heterojunction HEA (FeMnMoRuIr) zinc sulfide (ZnS) (HEA@ZnS) synthesized that exhibits enhanced activities. Moreover, hydrogel containing zein, sodium alginate, HEA@ZnS (ZeAHZ) antibacterial properties pro-osteogenic capability fabricated. Under acidic conditions, triggered by ultrasound, effect ZeAHZ enhances peroxidase-like sonodynamic efficiency produces large amount reactive oxygen species (ROS, ·O2- ·OH) collaboratively eliminating bacteria. superoxide-like effect-enhanced catalase-like scavenge ROS (·O2- H2O2) produce due cascade reaction, which provides favorable microenvironment cell growth. Further, generates electrical stimulation significantly promotes osteoblast proliferation differentiation. This study opens up new path designing biomaterial production/elimination pro-osteogenesis stimulation, has great potential accelerating regeneration.

Language: Английский

Two-Dimensional Materials in Bioelectronics DOI
Navid Rabiee

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: 189, P. 118279 - 118279

Published: April 23, 2025

Language: Английский

Citations

0
High-Entropy Alloy/Zinc Sulfide Heterojunction-Based Hydrogel for Eliminating Bacteria and Stimulating Osteoblast Response DOI

Young-Fa Lin,

Qin Zhang,

Shangyu Xie

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Integration of a high-entropy alloy (HEA) with nanozyme activity and piezoelectric material piezoelectricity is promising strategy to develop novel biofunctional for the repair infectious bone defects. Herein, heterojunction HEA (FeMnMoRuIr) zinc sulfide (ZnS) (HEA@ZnS) synthesized that exhibits enhanced activities. Moreover, hydrogel containing zein, sodium alginate, HEA@ZnS (ZeAHZ) antibacterial properties pro-osteogenic capability fabricated. Under acidic conditions, triggered by ultrasound, effect ZeAHZ enhances peroxidase-like sonodynamic efficiency produces large amount reactive oxygen species (ROS, ·O2- ·OH) collaboratively eliminating bacteria. superoxide-like effect-enhanced catalase-like scavenge ROS (·O2- H2O2) produce due cascade reaction, which provides favorable microenvironment cell growth. Further, generates electrical stimulation significantly promotes osteoblast proliferation differentiation. This study opens up new path designing biomaterial production/elimination pro-osteogenesis stimulation, has great potential accelerating regeneration.

Language: Английский

Citations

0