Highly Selective AIEgen‐Based “Turn On” Fluorescent Imaging for Inflammation Detection

Luminescence, Journal Year: 2025, Volume and Issue: 40(1)

Published: Jan. 1, 2025

ABSTRACT Hypochlorous acid (HClO) is released by immune cells in the system, and it helps body fight off infections inflammation killing bacteria, viruses, other pathogens. However, tissue damage or apoptosis may also be induced excess HClO. On this basis, we designed probe TPE‐NS choosing tetraphenylethylene (TPE) as luminescent unit dimethylthiocarbamoyl chloride recognition site. By Gaussian's transition state calculations, HClO will cut photoinduced electron transfer (PET) effect of hydrolysis reaction, thus emitting strong fluorescence. has rapid excellent specificity for HClO, limit detection 7.27 μM. Finally, was successfully used visualization endogenous exogenous cell experiments.

Language: Английский

Near-infrared light-triggered in situ self-assembly nanomedicine for treating antibiotic-resistant bacterial infection

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161303 - 161303

Published: March 1, 2025

Language: Английский