Advances and challenges of medicine and food homology earthworms: active ingredients, efficacy and quality control DOI

Siqi Lu,

Xiaoqin Xie, Bangshun He

et al.

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 105065 - 105065

Published: May 1, 2025

Language: Английский

Pharmacological effects of bioactive agents in earthworm extract: A comprehensive review DOI Creative Commons
Zihan Zhu, Xinyi Deng, Wenqing Xie

et al.

Animal Models and Experimental Medicine, Journal Year: 2024, Volume and Issue: 7(5), P. 653 - 672

Published: July 3, 2024

Abstract This review compiles information from the literature on chemical composition, pharmacological effects, and molecular mechanisms of earthworm extract (EE) suggests possibilities for clinical translation EE. We also consider future trends concerns in this domain. summarize bioactive components EE, including G‐90, lysenin, lumbrokinase, antimicrobial peptides, serine protease (ESP), polyphenols, detail antitumor, antithrombotic, antiviral, antibacterial, anti‐inflammatory, analgesic, antioxidant, wound‐healing, antifibrotic, hypoglycemic activities action EE based existing vitro vivo studies. further propose potential anticancer lipid‐modifying therapies, its promise as source a novel agent wound healing resistance to antibiotic tolerance. The enzyme lumbrokinase embodies highly effective anticoagulant thrombolytic properties has advantage not causing bleeding phenomena due hyperfibrinolysis. Its antifibrotic can reduce excessive accumulation extracellular matrix. glycolipoprotein G‐90 effectively scavenge reactive oxygen groups protect cellular tissues oxidative damage. Earthworms have evolved well‐developed defense mechanism fight against microbial infections, agents shown good fungal, viral experiments alleviate inflammatory responses caused by reducing pain. Recent studies highlighted role lowering blood glucose. shows high medicinal value is expected be many compounds.

Language: Английский

Citations

4
Identification of 2’-deoxyguanosine for an α-amylase inhibitor in the extracts of the earthworm Eisenia fetida and characterization of its inhibitory activity against porcine pancreatic α-amylase DOI

Masako Ogasawara,

Katsuhiro Yoshii,

Jun Wada

et al.

Enzyme and Microbial Technology, Journal Year: 2025, Volume and Issue: 185, P. 110604 - 110604

Published: Feb. 4, 2025

Language: Английский

Citations

0
Efficient hydrolysis of coagulated porcine blood by a purified lumbrokinase from Eisenia fetida DOI
Xuan Xin,

Yuhua Huang,

Mengmeng Zhang

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106655 - 106655

Published: April 1, 2025

Language: Английский

Citations

0
Advances and challenges of medicine and food homology earthworms: active ingredients, efficacy and quality control DOI

Siqi Lu,

Xiaoqin Xie, Bangshun He

et al.

Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 105065 - 105065

Published: May 1, 2025

Language: Английский

Citations

0