Ethical and legal considerations in normothermic regional perfusion for donation after circulatory death DOI
O Walker, Giuliano Testa, Anji Wall

et al.

Current Opinion in Critical Care, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Purpose of review This study aims to examine the ethical and legal discourse surrounding normothermic regional perfusion (NRP) for donation after circulatory death (DCD). Recent findings NRP is well established within Europe but faces challenges in US not utilized a variety other countries. compliance with dead donor rule (DDR) Uniform Declaration Death Act (UDDA) most significant recently addressed issue. Additionally, procedures raise concerns regarding public education, informed consent, engagement, trust. Inconsistent regulation – such as US– cause concern anticipated increase frequency support organ recovery transplantation. There no single repository technical outcome data practice refinement key aspect given variation between centers Summary NRP-based presents be by transplantation clinicians organizations conjunction representatives. Additional inquiry into determination death, family information needs authorization, coordinated needed ensure that are appropriately addressed. Public engagement essential bolster preserve

Language: Английский

Challenges and opportunities in organ donation after circulatory death DOI Creative Commons

Vidgren Mathias,

Delorme Capucine,

Gabriel C. Oniscu

et al.

Journal of Internal Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

Abstract In recent years, there has been resurgence in donation after circulatory death (DCD). Despite that, the number of organs transplanted from these donors remains low due to concerns about their function and a lack an objective assessment at time donation. This overview examines current DCD practices classification modifications accommodate regional perspectives. Several risk factors underscore reluctance accept organs, we discuss modern strategies mitigate them. The advent machine perfusion technology revolutionized field transplantation, leading improved outcomes better organ usage. With many our disposal, is urgent need for comparative trials determine optimal use technologies each donated type. Additional progress defining therapeutic repair damage sustained during dying process should further improve utilization outcomes. However, wide variability access organizational efforts be doubled up with consensus on key ethical issues that still surround era perfusion.

Language: Английский

Citations

0
Ethical and legal considerations in normothermic regional perfusion for donation after circulatory death DOI
O Walker, Giuliano Testa, Anji Wall

et al.

Current Opinion in Critical Care, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Purpose of review This study aims to examine the ethical and legal discourse surrounding normothermic regional perfusion (NRP) for donation after circulatory death (DCD). Recent findings NRP is well established within Europe but faces challenges in US not utilized a variety other countries. compliance with dead donor rule (DDR) Uniform Declaration Death Act (UDDA) most significant recently addressed issue. Additionally, procedures raise concerns regarding public education, informed consent, engagement, trust. Inconsistent regulation – such as US– cause concern anticipated increase frequency support organ recovery transplantation. There no single repository technical outcome data practice refinement key aspect given variation between centers Summary NRP-based presents be by transplantation clinicians organizations conjunction representatives. Additional inquiry into determination death, family information needs authorization, coordinated needed ensure that are appropriately addressed. Public engagement essential bolster preserve

Language: Английский

Citations

0