Unveiling Hierarchical Self‐Assembly of Triazolylferrocenyl Dendrimers: Producing Non‐Traditional Intrinsically Green Fluorescent Vesosomes for Nanotheranostics DOI
Carolyne B. Braga, Gabriel Perli, Qi Wang

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(32)

Published: Sept. 15, 2024

Abstract Dendrimers and supramolecular chemistry continue to fascinate researchers due the endless unrevealed potential of their combination. This study investigates self‐assembly process a series hydrophobic triazolylferrocenyl dendrimers in aqueous medium. Deep investigation through NMR spectroscopy, absorption UV–vis spectroscopy along with theoretical simulations demonstrates that ferrocenyl moieties interact intramolecularly intermolecularly driving process. Data obtained by DLS, NTA, SEM, TEM, EF‐TEM demonstrate these dendrimers, water, spontaneously self‐assemble hierarchical The first into uniform nanovesicles, which turn larger vesosomes. resulting vesosomes emit green non‐traditional intrinsic fluorescence, is property emerged from self‐assembled architectures. are efficiently uptaken cancer cells induce significant cytotoxic activity against cell line MCF‐7, up submicromolar concentration. Positive dendritic effects identified fluorescence intensity vesosomes, follow trend G0‐9Fc < G1‐27Fc G2‐81Fc. work showcases remarkable combining two dynamic fields chemistry, resulted fluorescent capable performing dual role imaging killing, applications nanotheranostics.

Language: Английский

Dendritic metallodrugs: An overview of their anticancer properties DOI
Anne‐Marie Caminade, Vania Bernardes‐Génisson, Aurélien Hameau

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 535, P. 216606 - 216606

Published: March 23, 2025

Language: Английский

Citations

0
Nanoarchitectonics for Biomedical Research: Post‐Nanotechnology Materials Approach for Bio‐Active Application DOI Creative Commons
Katsuhiko Ariga

Advanced NanoBiomed Research, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Nanoarchitectonics, as a post‐nanotechnology concept, represents methodology for the construction of functional materials employing atoms, molecules, and nanomaterials essential components. The overarching objective nanoarchitectonics is to develop systems comprising multiple units assembled in hierarchical manner, observed biological systems. Nevertheless, such challenging endeavor. It would be prudent, therefore, initially focus on development that interact with complex structures living organisms. Accordingly, this review article addresses topic nanoarchitecture it pertains biomedical applications. This examines current trends research presents examples studies support concept its applications fields. presented are follows: i) molecular developments, which mainly based design assembly; ii) material examples, using components; iii) porous materials, will summarized under heading pore‐engineered due their special structure. Finally, provides an overview these discusses future prospects.

Language: Английский

Citations

2
Unveiling Hierarchical Self‐Assembly of Triazolylferrocenyl Dendrimers: Producing Non‐Traditional Intrinsically Green Fluorescent Vesosomes for Nanotheranostics DOI
Carolyne B. Braga, Gabriel Perli, Qi Wang

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(32)

Published: Sept. 15, 2024

Abstract Dendrimers and supramolecular chemistry continue to fascinate researchers due the endless unrevealed potential of their combination. This study investigates self‐assembly process a series hydrophobic triazolylferrocenyl dendrimers in aqueous medium. Deep investigation through NMR spectroscopy, absorption UV–vis spectroscopy along with theoretical simulations demonstrates that ferrocenyl moieties interact intramolecularly intermolecularly driving process. Data obtained by DLS, NTA, SEM, TEM, EF‐TEM demonstrate these dendrimers, water, spontaneously self‐assemble hierarchical The first into uniform nanovesicles, which turn larger vesosomes. resulting vesosomes emit green non‐traditional intrinsic fluorescence, is property emerged from self‐assembled architectures. are efficiently uptaken cancer cells induce significant cytotoxic activity against cell line MCF‐7, up submicromolar concentration. Positive dendritic effects identified fluorescence intensity vesosomes, follow trend G0‐9Fc < G1‐27Fc G2‐81Fc. work showcases remarkable combining two dynamic fields chemistry, resulted fluorescent capable performing dual role imaging killing, applications nanotheranostics.

Language: Английский

Citations

1