Angewandte Chemie,
Journal Year:
2022,
Volume and Issue:
134(46)
Published: Sept. 20, 2022
Abstract
Catalytic
reduction
of
carboxylic
acids
and
derivatives
all
the
way
to
their
corresponding
methyl‐compounds
is
very
rare
still
challenging
for
homogeneous
transition‐metal
catalysis.
Herein,
we
report
an
unprecedented
general
catalytic
exhaustive
functional
group
straightforwardly
a
methyl
group.
This
reaction
was
achieved
using
earth‐abundant
readily
available
titanium
as
catalyst.
Our
system
has
broad
tolerance
works
various
other
types
oxo‐chemicals
such
alcohols,
aldehydes,
ketones,
lactones,
carboxylates
(>100
examples).
Preliminary
mechanistic
studies
revealed
that
in
situ‐generated
Ti
III
−H
species
vital
this
transformation.
Angewandte Chemie International Edition,
Journal Year:
2022,
Volume and Issue:
61(46)
Published: Sept. 20, 2022
Catalytic
reduction
of
carboxylic
acids
and
derivatives
all
the
way
to
their
corresponding
methyl-compounds
is
very
rare
still
challenging
for
homogeneous
transition-metal
catalysis.
Herein,
we
report
an
unprecedented
general
catalytic
exhaustive
functional
group
straightforwardly
a
methyl
group.
This
reaction
was
achieved
using
earth-abundant
readily
available
titanium
as
catalyst.
Our
system
has
broad
tolerance
works
various
other
types
oxo-chemicals
such
alcohols,
aldehydes,
ketones,
lactones,
carboxylates
(>100
examples).
Preliminary
mechanistic
studies
revealed
that
in
situ-generated
TiIII
-H
species
vital
this
transformation.
Angewandte Chemie International Edition,
Journal Year:
2022,
Volume and Issue:
61(49)
Published: Oct. 12, 2022
Secondary
α,α-dialkyl
boronates
are
widely
used
due
to
their
great
versatility.
Herein
we
report
an
unprecedented
deoxygenative
alkylboration
of
aldehydes,
a
facile
method
access
this
type
products.
A
sequence
difunctionalization
can
be
obtained
smoothly
from
the
readily
available
aldehydes
in
only
two
steps.
This
rather
than
conventional
alkenes
also
opens
new
possibilities
within
field.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(8), P. 5605 - 5613
Published: Feb. 14, 2024
Carbonyl
is
highly
accessible
and
acts
as
an
essential
functional
group
in
chemical
synthesis.
However,
the
direct
catalytic
deoxygenative
functionalization
of
carbonyl
compounds
via
a
putative
metal
carbene
intermediate
formidable
challenge
due
to
requirement
high
activation
energy
for
cleavage
strong
C═O
double
bonds.
Here,
we
report
class
bench
stable
readily
available
Cp*Mo(II)-complexes
efficient
deoxygenation
catalysts
that
could
catalyze
intermolecular
coupling
with
alkynes.
Enabled
by
this
powerful
Cp*Mo(II)-catalyst,
various
valuable
heteroarenes
(10
different
classes)
were
obtained
generally
good
yields
remarkable
chemo-
regioselectivities.
Mechanistic
studies
suggested
reaction
might
proceed
sequence
bonds
cleavage,
carbene-alkyne
metathesis,
cyclization,
aromatization
processes.
This
strategy
not
only
provided
general
platform
rapid
preparation
but
also
opened
new
window
applications
Cp*Mo(II)-catalysts
organic
Angewandte Chemie,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 11, 2025
Abstract
We
present
a
method
of
deoxygenative
deuteration
aldehydes
(DDA)
over
heterogeneously
superwetting
porous
carbon‐supported
palladium
catalyst
(Pd/SPC),
which
is
efficient
for
the
synthesis
deuterated
aromatic
compounds
with
‐CD
3
group.
Exemplified
by
DDA
reaction
2‐naphthaldehyde
(2‐NAL)
to
2‐methylnaphthalene
(2‐MNE),
total
deuterium
incorporation
radio
in
resultant
hydrocarbons
was
higher
than
95%
and
selectivity
toward
2‐MNE‐
d
reached
87%.
The
impressed
catalytic
activity
found
relevant
combined
effect
surface
wettability
electron‐rich
properties
Pd
species
this
kind
heterogeneous
Pd/SPC
catalyst.
Mechanistic
studies
suggest
successive
pathway,
that
is,
hydrogen
isotope
exchange
(HIE),
addition,
ultimate
cost‐effective
D
2
O/H
conditions.
situ‐formed
from
first
step
HIE
between
H
O
can
be
readily
captured
centers,
then
boost
subsequent
deuterogenolysis
C─O
bonds
through
alcohol
intermediates
formation
.
This
work
provides
design
principle
catalysts
targeted
labeling
aldehyde
substrates
may
inspire
development
alternative
techniques
beyond
dominated
homogeneous
catalysis.
ChemCatChem,
Journal Year:
2024,
Volume and Issue:
16(9)
Published: Jan. 10, 2024
Abstract
The
broad
applications
of
primary
alkyl
amines
in
various
fields
have
spurred
extensive
interests
synthetic
organic
chemistry.
Recently,
the
reductive
amination
carboxylic
acids
has
become
an
attractive
and
practical
strategy
for
synthesizing
amines,
due
to
their
wide
availability
bench
stability.
However,
inherent
stability
higher
oxidation
state
render
this
new
with
challenges.
This
Concept
provides
a
summary
recent
advancements
aminations
acids,
specifically
focusing
on
catalytic
tactics,
underlying
mechanisms,
synthesis
valuable
products.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2024,
Volume and Issue:
12(6), P. 2162 - 2171
Published: Jan. 30, 2024
Hydrodeoxygenation
(HDO)
reactions
are
important
processes
in
the
fields
of
bioenergy
and
biorefining,
as
they
enable
conversion
biomass
into
valuable
products
that
can
replace
fossil
fuels
reduce
greenhouse
gas
emissions.
The
efficient
utilization
solar
energy
for
boosting
HDO
is
great
significance
achieving
ecological
chemistry
a
sustainable
manner.
However,
application
photocatalysts
severely
restricted
by
inadequate
spectrum,
rapid
recombination
photogenerated
carriers,
slow
catalytic
kinetics.
Here,
we
demonstrate
Pd/HxWO3–y
catalyst
prepared
facile
H2
reduction
process
displays
activity
benzophenone
to
diphenylmethane
with
aid
light
irradiation
owing
its
surface
plasmon
resonance
(SPR)
effect.
forms
large
number
hydroxyl
groups
trace
oxygen
defects
on
Pd/WO3
surface,
intercalated
H
atoms
enrich
free
electrons,
resulting
plasmonic
absorption
under
visible-NIR
irradiation.
Photoelectrochemical
characterization
situ
Fourier
transform
infrared
(FT-IR)
spectroscopy
indicate
hot
electron
generation
electric
field
enhancement
effect
during
photoassisted
reaction,
which
promotes
activation
C═O
bond
enhance
reaction's
efficiency.
This
experiment
establishes
feasible
approach
effectively
utilize
reaction
ketones
mild
conditions
creating
an
intriguing
catalysis
features.
International Journal of Environmental & Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 12
Published: March 1, 2024
Cooking,
particularly
frying,
is
a
significant
contributor
to
indoor
air
pollution,
which
has
the
potential
make
carbonyls
due
characteristics
of
edible
oils.
Many
studies
have
measured
emitted
during
such
as
acetaldehyde
(ACT)
and
acrolein
(ACR).
However,
there
been
no
comprehensive
study
estimate
their
generation
rate.
Therefore,
this
aims
meta-analyse
concentrations
ACT
ACR
from
frying
process
at
emission
point
assess
corresponding
inhalation
risk
under
two
ventilation
system
scenarios
(on/off).
The
for
ozone
formation
these
compounds
was
also
estimated
using
Monte-Carlo
simulation.
After
systematic
research
among
international
databases
Scopus
WOS,
2526
articles
were
identified.
Finally,
10
papers
(228
data
reports)
included
based
on
PRISMA
protocol
guideline.
results
showed
that,
pooled
concentration
0.079
0.154
mg/m3,
respectively.
Based
Monte
Carlo
simulation,
exposure
0.0041
0.0017
mg/m3
when
hood
switched
off
on,
A
similar
reduction
observed
(from
0.0079
0.0039
mg/m3)
scenarios.
Unlike
ACR,
non-carcinogenic
obtained
lower
than
one
both
scenarios,
did
not
indicate
any
risk.
cumulative
health
target
considerable.
Cancer
estimations
in
association
with
that
each
mg
form
0.3
1
ozone,
