Regio- and diastereoselective synthesis of thioxothiazolidin- indolin-2-ones, oxoindolin-carbamodithioate hybrids, and their base-catalyzed conversion into dispirocyclopentanebisoxindoles
Abstract
In
this
publication,
we
reported
a
regio-,
diastereoselective,
and
kinetically
controlled
reaction
for
synthesizing
thioxothiazolidin-indolin-2-ones,
oxoindolin-carbamodithioate
hybrids,
their
base-catalyzed
conversion
into
dispirocyclopentanebisoxindoles.
Obtaining
only
the
kinetic
thioxothiazolidin-indolin-2-one
products
together
with
straightforward
to
dispirocyclopentanebisoxindoles,
excellent
regio-
diastereoselectivity,
easy
workup,
one-pot
synthetic
operation
are
considerable
advantages
of
work.
Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: May 15, 2024
Language: Английский