Water-Soluble Dual-Channel Fluorescent Probe for Sensitive Detection of Biothiols In Vitro and In Vivo DOI
Zhenbo Gao,

Hang Yang,

Lingzi Ran

et al.

ACS Applied Bio Materials, Journal Year: 2023, Volume and Issue: 6(12), P. 5828 - 5835

Published: Dec. 6, 2023

Benefiting from high spatiotemporal resolution, deep tissue penetration, and excellent sensitivity, fluorescence imaging technology has been widely applied in cancer diagnosis treatment. In recent years, a large number of fluorescent probes for monitoring the levels endogenous biothiols have reported, which significant implications However, most still suffer poor biological compatibility easy attachment by environment. This work presents development water-soluble dual-channel probe, named MAL-NBD, sensitively detecting biothiols. Nonfluorescent MAL-NBD is transformed into groups MAL NBD-SR/NR through nucleophilic substitution biologically active thiols, producing signals precise detection thiols. Taking advantage biocompatibility low biotoxicity, successfully used HeLa cells zebrafish larvae, promoting its potential application thiols involved physiological pathological processes.

Language: Английский

Fluorescent chemosensors facilitate the visualization of plant health and their living environment in sustainable agriculture DOI Creative Commons

Yang-Yang Gao,

Jie He,

Xiao-Hong Li

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(13), P. 6992 - 7090

Published: Jan. 1, 2024

Globally, 91% of plant production encounters diverse environmental stresses. Fluorescent chemosensors are effective for monitoring health and environment that promotes the development sustainable agriculture.

Language: Английский

Citations

17
A Rapid and Specific Fluorescent Probe based on ESIPT-AIE-Active for Copper Ion Quantitative Detection in Food and Environmental Samples DOI

Xiaomei Ren,

Ji Liu, Yating Zhang

et al.

Talanta, Journal Year: 2025, Volume and Issue: 294, P. 128188 - 128188

Published: April 18, 2025

Language: Английский

Citations

0
Water-Soluble Dual-Channel Fluorescent Probe for Sensitive Detection of Biothiols In Vitro and In Vivo DOI
Zhenbo Gao,

Hang Yang,

Lingzi Ran

et al.

ACS Applied Bio Materials, Journal Year: 2023, Volume and Issue: 6(12), P. 5828 - 5835

Published: Dec. 6, 2023

Benefiting from high spatiotemporal resolution, deep tissue penetration, and excellent sensitivity, fluorescence imaging technology has been widely applied in cancer diagnosis treatment. In recent years, a large number of fluorescent probes for monitoring the levels endogenous biothiols have reported, which significant implications However, most still suffer poor biological compatibility easy attachment by environment. This work presents development water-soluble dual-channel probe, named MAL-NBD, sensitively detecting biothiols. Nonfluorescent MAL-NBD is transformed into groups MAL NBD-SR/NR through nucleophilic substitution biologically active thiols, producing signals precise detection thiols. Taking advantage biocompatibility low biotoxicity, successfully used HeLa cells zebrafish larvae, promoting its potential application thiols involved physiological pathological processes.

Language: Английский

Citations

5