Research progress on selenium system in cancer therapy: Focus on interface modifications and improvement of interactions DOI
Hui He,

Dingding Huang,

Peng Xie

et al.

Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: unknown, P. 105642 - 105642

Published: Dec. 1, 2024

Language: Английский

Progress in the Application of Nanomaterials for Radio Sensitization in Tumor Radiotherapy DOI

淞名 吴

Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(01), P. 1963 - 1971

Published: Jan. 1, 2025

Language: Английский

Citations

0
Radio‐Activated Selenium‐Doped Janus Ag/Ag2SexSy Nanoparticles for Precise Cancer NIR‐II Fluorescence Imaging and Radiosensitization Therapy DOI Creative Commons

Kang Zhu,

Zhanyuan Li,

Jingjing Cao

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Abstract The efficacy of radiotherapy (RT) is often limited by insufficient tumor selectivity and suboptimal therapeutic responses. To overcome these problems, a new kind selenium‐doped Ag/Ag 2 S Janus nanoparticles (Ag/Ag Se x y JNPs) presented as radio‐responsive molecular probes for precise imaging enhanced radiosensitization. By adjusting the selenium precursor input, heterojunction with tunable doping ratios are synthesized, optimizing X‐ray absorption energy storage properties. Upon irradiation, JNPs interact overexpressed hydrogen peroxide (H O ) in cells, generating highly toxic hydroxyl radicals (·OH), which effectively induce cell apoptosis. Additionally, Selenium incorporation improves electron–hole pair separation efficiency enhances photocurrent response, promoting increased electron transfer ·OH generation, thus amplifying reactive oxygen species (ROS) production enhancing Furthermore, fluorescence “OFF‐ON” mechanism, triggered H ‐induced etching silver allows real‐time monitoring levels via second near‐infrared window (NIR‐II) (FL) “Turn On”, delineates boundaries RT reduce side effects to normal tissue. This dual‐functional platform not only enables tracking but also outcomes, offering promising approach precision cancer treatment.

Language: Английский

Citations

0
Mechanically robust and rapid room temperature self-healing waterborne polyurethane with three cross-linking networks based on triple dynamic bonds DOI
Haonan Chen, Yong Jin, Rong Zhou

et al.

Polymer, Journal Year: 2024, Volume and Issue: 317, P. 127949 - 127949

Published: Dec. 11, 2024

Language: Английский

Citations

3
Research progress on selenium system in cancer therapy: Focus on interface modifications and improvement of interactions DOI
Hui He,

Dingding Huang,

Peng Xie

et al.

Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: unknown, P. 105642 - 105642

Published: Dec. 1, 2024

Language: Английский

Citations

2