Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Feb. 29, 2024
Abstract
The
photochemical
properties
of
Electron
Donor-Acceptor
(EDA)
complexes
present
exciting
opportunities
for
synthetic
chemistry.
However,
these
strategies
often
require
an
inert
atmosphere
to
maintain
high
efficiency.
Herein,
we
develop
EDA
complex
photocatalytic
system
through
rational
design,
which
overcomes
the
oxygen-sensitive
limitation
traditional
systems
and
enables
aerobic
oxygenation
reactions
dioxygen
activation.
mild
oxidation
transfers
electrons
from
donor
effective
catalytic
acceptor
upon
visible
light
irradiation,
are
subsequently
captured
by
molecular
oxygen
form
superoxide
radical
ion,
as
demonstrated
specific
fluorescent
probe,
dihydroethidine
(DHE).
Furthermore,
this
visible-light
mediated
oxidative
protocol
is
successfully
applied
in
boronic
acids.
We
believe
that
activation
strategy
enabled
not
only
provides
a
practical
approach
but
also
promotes
design
application
photocatalysis
under
ambient
conditions.
Angewandte Chemie International Edition,
Journal Year:
2020,
Volume and Issue:
59(23), P. 8907 - 8911
Published: March 9, 2020
Abstract
A
straightforward
multicomponent
decarboxylative
cross
coupling
of
redox‐active
esters
(N‐hydroxyphthalimide
ester),
sodium
dithionite,
and
electrophiles
was
established
to
construct
sterically
bulky
sulfones.
The
inorganic
salt
dithionite
not
only
served
as
the
sulfur
dioxide
source,
but
also
acted
an
efficient
radical
initiator
for
decarboxylation.
Notably,
diverse
naturally
abundant
carboxylic
acids
artificially
prepared
carboxyl‐containing
drugs
with
multiple
heteroatoms
sensitive
functional
groups
successfully
underwent
this
sulfonylation
provide
tertiary
Mechanistic
studies
further
demonstrated
that
decarboxylation
rate‐determining
step
occurred
via
a
single‐electron
transfer
(SET)
process
assistance
dithionite.
Green Chemistry,
Journal Year:
2019,
Volume and Issue:
22(2), P. 433 - 438
Published: Nov. 26, 2019
The
first
example
of
selective
oxidation
sulfides
to
sulfones
and
sulfoxides
using
molecular
oxygen
under
clean
conditions
was
established.
desired
products
could
be
easily
collected
through
recrystallization
in
large-scale
preparation.
Green Chemistry,
Journal Year:
2020,
Volume and Issue:
23(1), P. 496 - 500
Published: Nov. 26, 2020
A
practical
method
for
the
switchable
synthesis
of
sulfoxides
and
sulfones
through
visible-light-initiated
CF3SO2Na/2-butoxyethyl
ether
synergistic
catalyzed
oxygenation
sulfides
was
developed.
Advanced Synthesis & Catalysis,
Journal Year:
2020,
Volume and Issue:
362(13), P. 2609 - 2614
Published: May 1, 2020
Abstract
With
ethylene
glycol
as
a
green
solvent,
general
transition
metal‐free
photocatalytic
system
using
9‐mesityl‐10‐methylacridinium
perchlorate
(Acr
+
−Mes
⋅
ClO
4
−
)
catalyst
was
developed
for
the
synthesis
of
sulfone‐containing
heterocycles
including
thioflavones,
oxindoles,
and
quinoline‐2,4(1
H
,3
)‐diones
through
cascade
sulfonation/cyclization
reactions
under
irradiation
blue
light
at
room
temperature.
magnified
image
Advanced Synthesis & Catalysis,
Journal Year:
2020,
Volume and Issue:
362(11), P. 2143 - 2149
Published: Jan. 8, 2020
Abstract
A
sustainable
and
cost‐effective
protocol
for
direct
aminomethylation
of
imidazo‐fused
heterocycles
by
decarboxylative
coupling
reaction
N
‐phenylglycines
with
in
the
presence
CsPbBr
3
under
irradiation
visible
light
has
been
developed.
This
is
first
example
‐catalyzed
heterocycles.
The
eminent
advantage
this
work
that,
easily
prepared
can
be
used
at
least
5
times
without
obvious
reduction
its
activity,
exhibiting
high
catalyst
economic
feature.
magnified
image
Journal of the American Chemical Society,
Journal Year:
2021,
Volume and Issue:
143(9), P. 3628 - 3637
Published: Feb. 26, 2021
A
highly
selective,
environmentally
friendly,
and
scalable
electrochemical
protocol
for
the
construction
of
α-acyloxy
sulfides,
through
synergistic
effect
self-assembly-induced
C(sp3)–H/O–H
cross-coupling,
is
reported.
It
features
exceptionally
broad
substrate
scope,
high
regioselectivity,
gram-scale
synthesis,
complex
molecules,
applicability
to
a
variety
nucleophiles.
Moreover,
soft
X-ray
absorption
technique
series
control
experiments
have
been
utilized
demonstrate
pivotal
role
self-assembly
substrates,
which
indeed
responsible
excellent
compatibility
precise
regioselectivity
in
our
protocol.
ACS Applied Materials & Interfaces,
Journal Year:
2021,
Volume and Issue:
13(17), P. 20137 - 20144
Published: April 22, 2021
A
zirconium-based
metal–organic
framework
(MOF)
was
successfully
constructed
via
solvothermal
assembly
of
a
triphenylamine-based
tricarboxylate
ligand
and
Zr(IV)
salt,
the
structure
simulation
which
revealed
that
it
possesses
two-dimensional
layered
with
relatively
rare
dodecnuclear
Zr12
cluster
as
inorganic
building
unit.
The
inherent
photo-responsive
property
derived
from
incorporated
photochromic
triphenylamine
groups
combined
its
high
stability
makes
MOF
an
efficient
heterogeneous
photocatalyst
for
oxidation
sulfides,
is
fundamentally
important
reaction
type
in
both
environmental
pharmaceutical
industries.
photocatalytic
activity
first
investigated
under
various
conditions
thioanisole
representative
sulfide
substrate.
exhibited
efficiency
selectivity
on
aerobic
methanol
utilizing
molecular
oxygen
air
oxidant
blue
light
irradiation
10
h.
Its
performance
also
observed
when
extending
substrate
to
diverse
derivatives
even
sulfur-containing
nerve
agent
simulant
(2-chloroethyl
ethyl
sulfide).
broad
set
substrates
make
triphenylamine-incorporating
highly
promising
photocatalyst.
Organic Letters,
Journal Year:
2021,
Volume and Issue:
23(9), P. 3663 - 3668
Published: April 21, 2021
An
efficient
visible-light-assisted,
copper-catalyzed
sulfonylation
of
aryl
halides
with
sulfinates
is
reported.
In
our
protocol,
a
single
ligand
CuI
photocatalyst
formed
in
situ
was
used
the
photocatalytic
transformation.
Diverse
organosulfones
were
obtained
moderate
to
good
yields.
This
strategy
demonstrates
promising
approach
toward
synthesis
diverse
and
useful
organosulfones.
Green Chemistry,
Journal Year:
2021,
Volume and Issue:
24(1), P. 124 - 129
Published: Dec. 13, 2021
Stepwise
oxygenation
of
benzylic
molecules
with
uranyl
photocatalysis
was
realized
under
ambient
conditions.
The
accuracy
the
stepwise
ensured
by
tunability
redox
potential
in
through
solvents
and
additives.
