Journal of Nanomaterials,
Journal Year:
2022,
Volume and Issue:
2022(1)
Published: Jan. 1, 2022
Breast
cancer
is
the
most
common
diagnosed
in
women,
with
an
estimated
12%
of
women
United
States
affected
during
their
lifetime.
Researchers
have
demonstrated
that
early
detection,
diagnosis,
and
treatment
are
pivotal
to
increasing
survival.
The
advent
nanotechnology
has
yielded
several
novel
advances
available
modern
methods
within
clinic
detect
treat
breast
cancer.
Inorganic
nanoparticles
broadly
utilized
for
diagnosis
therapeutic
purposes.
Interestingly,
these
can
also
be
attached
tumor‐specific
ligands
used
deliver
chemotherapeutic
or
hormonal
agents
high
levels
tumor
selectivity.
Iron
oxide
one
commonly
nanomaterials,
which
attracted
much
attention
cancers,
owing
superparamagnetic
characteristics.
Computerized
tomography
magnetic
resonance
imaging
(MRI)
utilizing
iron‐based
promising
approaches
radiological
detection
Here,
we
discuss
roles
recent
applications
iron
diagnosing
treating
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: Aug. 4, 2023
Bacterial
cellulose
(BC)
is
generated
by
certain
species
of
bacteria
and
comprises
polysaccharides
with
unique
physical,
chemical,
mechanical
characteristics.
Due
to
its
outstanding
biocompatibility,
high
purity,
excellent
strength,
water
absorption,
highly
porous
structure,
bacterial
has
been
recently
investigated
for
biomedical
application.
However,
the
pure
form
hardly
used
as
a
material
due
some
inherent
shortcomings.
To
extend
applications
in
drug
delivery,
modifications
native
are
widely
improve
properties.
Usually,
can
be
carried
out
biological
methods.
In
this
review,
brief
introduction
production
fabrication
first
given,
followed
up-to-date
in-depth
discussions
modification.
Finally,
we
focus
on
potential
delivery
system.
Advanced Biology,
Journal Year:
2024,
Volume and Issue:
8(6)
Published: March 15, 2024
Abstract
Nucleic
acid
aptamers,
often
termed
“chemical
antibodies,”
are
short,
single‐stranded
DNA
or
RNA
molecules,
which
selected
by
SELEX.
In
addition
to
their
high
specificity
and
affinity
comparable
traditional
antibodies,
aptamers
have
numerous
unique
advantages
such
as
wider
identification
of
targets,
none
low
batch‐to‐batch
variations,
versatile
chemical
modifications,
rapid
mass
production,
lack
immunogenicity.
These
characteristics
make
a
promising
recognition
probe
for
scientific
research
even
clinical
application.
Aptamer‐functionalized
nanomaterials
now
emerged
drug
delivery
system
various
diseases
with
decreased
side‐effects
improved
efficacy.
this
review,
the
technological
strategies
generating
high‐affinity
biostable
introduced.
Moreover,
development
application
in
biomedicine
including
aptamer‐based
biosensors,
aptamer–drug
conjugates
aptamer
functionalized
is
comprehensively
summarized.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 3, 2025
Recently,
targeted
protein
degradation
(TPD)
strategies
have
emerged
as
a
promising
solution
to
tackle
undruggable
proteins.
While
most
TPD
target
intracellular
proteins,
limited
options
exist
for
targeting
extracellular
or
membrane
Herein,
cancer
specific
carbonic
anhydrase
IX
(CAIX)-targeting
supramolecular
nanofibrous
lysosome-targeting
chimeras
(Supra-LYTAC)
is
reported.
Two
self-assembling
amphiphilic
peptides
are
synthesized:
one
that
interacts
with
the
of
interest
(POI),
and
another
mediates
lysosomal
endocytosis
by
cancer-specific
enzyme.
Notably,
these
two
co-assemble
into
nanofibers
capable
cells
in
spatiotemporal
manner.
Through
dynamic
multivalent
binding,
ternary
complex
form
(supramolecular
chimeric
nanostructure;
CAIX-nanofiber-POI),
which
undergoes
internalization
lysosomes
where
POI
degraded
through
catalytic
activity.
This
study
demonstrates
potential
approaches
expand
scope
LYTAC
technology,
offering
new
opportunities
designing
future.
Journal of Nanomaterials,
Journal Year:
2022,
Volume and Issue:
2022(1)
Published: Jan. 1, 2022
Breast
cancer
is
the
most
common
diagnosed
in
women,
with
an
estimated
12%
of
women
United
States
affected
during
their
lifetime.
Researchers
have
demonstrated
that
early
detection,
diagnosis,
and
treatment
are
pivotal
to
increasing
survival.
The
advent
nanotechnology
has
yielded
several
novel
advances
available
modern
methods
within
clinic
detect
treat
breast
cancer.
Inorganic
nanoparticles
broadly
utilized
for
diagnosis
therapeutic
purposes.
Interestingly,
these
can
also
be
attached
tumor‐specific
ligands
used
deliver
chemotherapeutic
or
hormonal
agents
high
levels
tumor
selectivity.
Iron
oxide
one
commonly
nanomaterials,
which
attracted
much
attention
cancers,
owing
superparamagnetic
characteristics.
Computerized
tomography
magnetic
resonance
imaging
(MRI)
utilizing
iron‐based
promising
approaches
radiological
detection
Here,
we
discuss
roles
recent
applications
iron
diagnosing
treating
