Photoinduced copper-catalyzed asymmetric radical three-component cross-coupling of 1,3-enynes with oxime esters and carboxylic acids DOI
Guoqing Li,

Fan-Rong Meng,

Wen‐Jing Xiao

et al.

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(11), P. 2773 - 2781

Published: Jan. 1, 2023

A regio- and enantioselective radical three-component coupling of 1,3-enynes, oxime esters, carboxylic acids through photoinduced copper catalysis is reported.

Language: Английский

Visible-light-driven regioselective carbocarboxylation of 1,3-dienes with organic halides and CO2 DOI

Chunlin Zhou,

Xinchao Wang, Lei Yang

et al.

Green Chemistry, Journal Year: 2022, Volume and Issue: 24(16), P. 6100 - 6107

Published: Jan. 1, 2022

An unprecedented visible-light-driven regioselective carbocarboxylation of 1,3-dienes with CO 2 using aryl and alkyl halides under mild conditions is reported herein.

Language: Английский

Citations

34
Asymmetric 1,2-oxidative alkylation of conjugated dienes via aliphatic C–H bond activation DOI
Lian‐Feng Fan, Rui Liu,

Xiao‐Yun Ruan

et al.

Nature Synthesis, Journal Year: 2022, Volume and Issue: 1(12), P. 946 - 955

Published: Nov. 3, 2022

Language: Английский

Citations

32
Copper‐Catalyzed Radical Enantioselective Carbo‐Esterification of Styrenes Enabled by a Perfluoroalkylated‐PyBox Ligand DOI

Zaicheng Nie,

Mong‐Feng Chiou,

Jinfeng Cui

et al.

Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 61(28)

Published: May 5, 2022

Abstract Chiral lactones are found in many natural products. The reaction of simple alkenes with iodoacetic acid is a powerful method to build lactones, but the enantioselective version this has not been implemented date. Herein, we report efficient catalytic radical carbo‐esterification styrenes enabled by newly developed Cu I ‐perfluoroalkylated PyBox system. Simple have converted useful chiral whose synthetic applications showcased. Mechanistic studies reveal that rare example an ligand‐decelerated system, which ligand decelerates reaction, still reduced amounts ligand. This uncommon system may inspire further consideration effect ligands asymmetric catalysis.

Language: Английский

Citations

30
Diversity-oriented synthesis of fluoroalkylated amines via the palladium-catalyzed divergent fluoroalkylamination of 1,3-dienes DOI
Fu Chen, Zhaosheng Zhang, Yuzhen Li

et al.

Chemical Communications, Journal Year: 2022, Volume and Issue: 58(37), P. 5614 - 5617

Published: Jan. 1, 2022

Herein, we reported the first versatile and expeditious protocol for diversity-oriented synthesis (DOS) of fluoroalkylated amines via photoinduced palladium-catalyzed cross coupling 1,3-dienes, fluoroalkyl iodides, which features excellent 3,4- 1,4-selectivity controlled by a broad substrate scope as well good function group tolerance, could be extended to late-stage modification bioactive molecules.

Language: Английский

Citations

29
Photoinduced copper-catalyzed asymmetric radical three-component cross-coupling of 1,3-enynes with oxime esters and carboxylic acids DOI
Guoqing Li,

Fan-Rong Meng,

Wen‐Jing Xiao

et al.

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(11), P. 2773 - 2781

Published: Jan. 1, 2023

A regio- and enantioselective radical three-component coupling of 1,3-enynes, oxime esters, carboxylic acids through photoinduced copper catalysis is reported.

Language: Английский

Citations

21