Zeitschrift für Kristallographie - New Crystal Structures,
Journal Year:
2023,
Volume and Issue:
239(1), P. 85 - 87
Published: Dec. 12, 2023
Abstract
C
37
H
36
Cl
2
OSi,
monoclinic
P
1
/
n
(no.
14),
a
=
10.4363(14)
Å,
b
17.128(2)
c
17.875(3)
β
90.934(2)°,
V
3194.8(8)
Å
3
,
Z
4,
R
gt
(
F
)
0.0491,
wR
ref
0.1449,
T
296.15
K.
Organic Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
10(18), P. 4488 - 4515
Published: Jan. 1, 2023
This
review
highlights
the
recent
advances
in
radical
acylated
difunctionalization
of
unsaturated
carbon–carbon
bonds
and
focuses
on
mechanistic
insights
these
transformations.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(10), P. 1673 - 1677
Published: March 7, 2023
A
photoredox/nickel
dual
catalytic
protocol
for
the
regioselective
three-component
carboacylation
of
alkenes
with
tertiary
and
secondary
alkyltrifluoroborates
as
well
acyl
chlorides
is
described.
This
redox-neutral
can
be
applied
to
rapid
synthesis
ketones
high
diversity
complexity
via
a
radical
relay
process.
Many
functional
groups,
allowing
various
commercially
available
chlorides,
alkyltrifluoroborates,
alkenes,
are
tolerated
under
these
mild
conditions.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(28), P. 5268 - 5272
Published: July 6, 2023
A
photoredox-catalyzed
divergent
1,2-dicarbonylation
and
hydroacylation
of
alkenes
with
acid
anhydride
is
presented.
This
approach
offers
a
mild
efficient
entry
to
1,4-dicarbonyl
compounds
bearing
all-carbon
quaternary
centers,
exhibiting
broad
substrate
scope
high
functional
group
compatibility.
Hydrocarbonylaltion
can
also
be
realized
by
simply
introducing
proton
source
the
reaction
system.
Mechanism
investigations
support
radical
addition/radical-polar
crossover
cascade.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(45), P. 8067 - 8071
Published: Nov. 8, 2023
A
visible-light-induced
β-acyl
difunctionalization
of
alkenes
with
acyl
oxime
esters
and
various
nucleophiles
was
developed
to
achieve
molecular
complexity
from
readily
available
raw
materials
via
oxidative
radical-polar
crossover.
variety
nucleophiles,
including
NH-sulfoximines,
indoles,
indazole,
trimethoxybenzene,
were
all
effectively
applicable
the
sustainable
reaction
system.
The
novel
synthetic
strategy
features
mild
conditions,
a
broad
substrate
scope
(39
examples),
easy
scale-up,
excellent
regioselectivity.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(62), P. 8107 - 8110
Published: Jan. 1, 2024
A
visible-light-induced
directed
decarboxylative
disulfuration
of
α-keto
acids
and
oxamic
was
developed.
As
a
result,
series
versatile
mono
acyl
disulfide
derivatives
synthesized
under
mild
sustainable
reaction
conditions.
This
protocol
has
broad
substrate
scope,
good
functional-group
tolerance,
excellent
synthetic
applications.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(49), P. 8877 - 8882
Published: Dec. 4, 2023
Herein,
we
disclose
a
nickel/photo-cocatalyzed
three-component
alkyl-acylation
of
aryl-substituted
alkenes
with
aldehydes
and
electron-withdrawing-group-activated
alkyl
bromides,
providing
straightforward
access
to
various
ketones
under
mild
ligand-free
conditions.
The
photocatalyst
TBADT
plays
dual
role
in
activating
the
acyl
C-H
bond
via
hydrogen
atom
transfer
reducing
C-Br
bromides
single-electron
transfer.
While
terminal
C-C
is
forged
through
polarity-matched
radical-type
addition,
nickel
likely
involved
acylation
step.
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 2, 2025
A
regioselective
1,2-carboacylation
protocol
of
alkenes
via
nickel/photoredox
dual
catalysis
has
been
successfully
developed
under
mild
conditions.
wide
range
alkyl
bromides,
α-oxocarboxylic
acids,
and
styrenes
proved
to
be
compatible
the
optimized
conditions,
affording
corresponding
products
in
up
91%
yields.
Mechanistically,
key
success
this
approach
is
temporal
orchestration
radical
generation:
nickel-catalyzed
halogen
atom
transfer
(XAT)
for
bromides
photoredox-driven
decarboxylation
acids.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
62(49)
Published: Oct. 3, 2023
Here,
we
show
the
conversion
of
unactivated
alkenes
into
α-branched
enones
via
regioselective
chloroacylation
with
acyl
chlorides.
The
method
relies
upon
initial
in
situ
generation
chlorine
radicals
directly
from
chloride
precursor
under
cooperative
nickel/photoredox
catalysis.
Subsequent
HCl
elimination
provides
and
α,β-unsaturated
esters
that
are
not
accessible
conventional
acylation
approaches
provide
other,
linear
constitutional
isomer.
Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(3), P. 1012 - 1012
Published: Jan. 1, 2023
The
cheap
and
readily
available
olefin
substrates
have
received
much
attention
for
the
synthesis
of
structurally
rich
high
value-added
ketones,
aldehydes,
carboxylic
acids
their
derivatives
via
α-acylation.Multicomponent
tandem
α-acylation
olefins
achieves
efficiency
selectivity
by
N-heterocyclic
carbene
or
transition
metal
catalysis,
albeit
with
narrow
reaction
modes
substrates.Rapid
growth
photocatalysis
in
organic
transformation
has
introduced
new
methodologies
to
undergo
broad
substrate
scope.The
research
progress
prospect
future
development
this
active
field
is
highlighted.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(35), P. 6522 - 6527
Published: Aug. 29, 2023
A
novel
three-component
α-acylated
difunctionalization
of
alkenes
strategy
has
been
developed
on
the
basis
a
direct
hydrogen
atom
transfer
(HAT)
process
photoinduced
acyl
azolium
salts.
With
simple
irradiation
without
catalyst,
variety
olefins
can
be
directly
converted
into
ketone
derivatives,
including
1,4-dione,
β-silyl
ketone,
1,5-dione,
etc.
Mechanistic
investigations
indicated
that
unique
reactivity
azonium
triplet
excited
state
is
crucial
to
strategy's
success.