Angewandte Chemie,
Journal Year:
2023,
Volume and Issue:
136(6)
Published: Nov. 2, 2023
Abstract
Cheap,
stable
and
easy‐to‐handle
Werner
ammine
salts
have
been
known
for
more
than
a
century;
but
they
rarely
used
in
organic
synthesis.
Herein,
we
report
that
the
hexammine
complex
[Ni(NH
3
)
6
]Cl
2
can
be
as
both
nitrogen
catalytic
nickel
source
allow
efficient
amination
of
aryl
chlorides
presence
amount
bipyridine
ligand
under
irradiation
390–395
nm
light
without
need
any
additional
catalysts.
More
80
chlorides,
including
20
drug
molecules,
were
aminated,
demonstrating
practicality
generality
this
method
synthetic
chemistry.
A
slow
NH
release
mechanism
is
operation,
obviating
problem
catalyst
poisoning.
Still
interestingly,
show
salt
easily
recovered
reused,
solving
difficult
recovery
transition
metal
The
protocol
thus
provides
an
new
strategy
synthesis
primary
amines.
Science,
Journal Year:
2024,
Volume and Issue:
383(6684), P. 750 - 756
Published: Feb. 15, 2024
Water
can
accelerate
a
variety
of
organic
reactions
far
beyond
the
rates
observed
in
classical
solvents.
However,
using
pure
water
as
solvent
introduces
solubility
constraints
that
have
limited
applicability
efficient
photochemistry
particular.
We
report
here
formation
aggregates
between
pairs
arenes,
heteroarenes,
enamines,
or
esters
with
different
electron
affinities
an
aqueous
medium,
leading
to
oil-water
phase
boundary
through
substrate
melting
point
depression.
The
active
hydrogen
atoms
reactants
engage
bonds
water,
thereby
accelerating
photochemical
reactions.
This
methodology
realizes
appealingly
simple
conditions
for
coupling
complex
solid
molecules,
including
drug
molecules
are
poorly
soluble
water.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(7)
Published: Jan. 3, 2024
Due
to
the
demanding
depolymerization
conditions
and
limited
catalytic
efficiency,
enhancing
lignin
valorization
remains
challenging.
Therefore,
lowering
bond
dissociation
energy
(BDE)
has
emerged
as
a
viable
strategy
for
achieving
mild
yet
highly
effective
cleavage
of
bonds.
In
this
study,
photocatalytic
semi-hydrogenation/reduction
utilizing
CsPbBr
ACS Central Science,
Journal Year:
2024,
Volume and Issue:
10(3), P. 529 - 542
Published: Feb. 26, 2024
Photoredox
catalytic
processes
offer
the
potential
for
precise
chemical
reactions
using
light
and
materials.
The
central
determinant
is
identified
as
interfacial
charge
transfer,
which
simultaneously
engenders
distinctive
behavior
in
overall
reaction.
An
in-depth
elucidation
of
main
mechanism
highlighting
complexity
transfer
can
occur
through
both
diffusive
direct
models,
revealing
its
sophisticated
design
complex
transformations.
fundamental
photophysics
uncover
these
comprehensive
applications
a
clue
future
development.
This
research
contributes
to
growing
body
knowledge
on
photoredox
catalysis
sets
stage
further
exploration
this
fascinating
area
research.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
63(6)
Published: Nov. 2, 2023
Cheap,
stable
and
easy-to-handle
Werner
ammine
salts
have
been
known
for
more
than
a
century;
but
they
rarely
used
in
organic
synthesis.
Herein,
we
report
that
the
hexammine
complex
[Ni(NH
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(25), P. 5323 - 5328
Published: June 17, 2024
Amino
acids
and
aromatic
nitrogen
heterocycles
are
widely
used
in
pharmaceuticals.
Herein,
we
present
an
effective
visible-light-driven
thiobenzoic
acid
(TBA)-catalyzed
decyanative
C(sp3)–H
heteroarylation
of
glycine
derivatives.
This
process
occurs
under
mild
straightforward
conditions,
affording
a
range
valuable
yet
challenging-to-obtain
α-heteroaryl
amino
Moreover,
this
organocatalytic
C(sp3)–C(sp2)
bond
formation
reaction
is
applicable
to
the
late-stage
modification
various
short
peptides.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
62(29)
Published: May 23, 2023
Abstract
The
activation
of
the
α‐C−H
bond
ketones
typically
requires
an
amine
and
a
directing
group
to
guide
reaction
selectivity
in
amine‐catalysis
carbonyl
chemistry.
For
ketone,
groups
are
also
required
control
selectivity.
Reported
herein
is
first
α‐alkylation
cyclic
absence
catalyst
group.
1
H
NMR,
XPS,
EPR
studies
DFT
calculations
indicate
that
α‐carbon
radical
intermediate
formed
through
direct
selective
inert
chelating
on
surface
colloidal
quantum
dots
(QDs).
Such
interaction
essential
for
weakening
C−H
bond,
as
exemplified,
using
CdSe
QDs
sole
photocatalyst
execute
alkylation
under
visible‐light
irradiation.
Without
group,
high
step‐
atom‐economy
transformation
redox‐neutral
condition
opens
new
way
functionalization
ACS Applied Nano Materials,
Journal Year:
2025,
Volume and Issue:
8(4), P. 1700 - 1708
Published: Jan. 15, 2025
Advancing
efficient
and
sustainable
catalytic
systems
for
organic
transformation
remains
a
pivotal
objective
in
contemporary
chemistry.
This
research
introduces
an
innovative
method
employing
visible
light-driven
quantum
dots
copper
photocatalysis
to
achieve
azide–alkyne
cycloaddition
(AAC)
reactions
at
room
temperature.
The
synergistic
action
of
(QDs)
catalysts
under
light
exposure
ensures
high
reaction
efficiency
regio-selectivity,
offering
ecofriendly
energy-saving
alternative
conventional
thermal
approaches.
In
this
study,
CdS
QDs
play
dual
role:
they
act
as
electron
donors,
reducing
Cu(II)
Cu(I),
enable
rapid
completion
light,
even
without
inert
atmosphere
or
any
sacrificial
donor.
use
immiscible
solvents
allows
easy
separation,
exhibit
impressive
properties.
demonstrates
turnover
number
(TON)
0.96
×
106
frequency
(TOF)
0.16
h–1.
Furthermore,
work
showcases
broad
substrate
compatibility,
tolerating
various
functional
groups
achieving
excellent
yields
up
99%
shorter
time
6
h,
thus
establishing
it
versatile
strategy
synthesizing
1,2,3-triazoles.
study
underscores
the
potential
merging
QD
with
metal
catalysis
promote
advancement
chemical
processes.
