Mechanical‐Force‐Induced Non‐spontaneous Dehalogenative Deuteration of Aromatic Iodides Enabled by Using Piezoelectric Materials as a Redox Catalyst DOI

Ruiling Qu,

Shan Wan, Xuemei Zhang

et al.

Angewandte Chemie, Journal Year: 2024, Volume and Issue: 136(28)

Published: April 30, 2024

Abstract The development of green and efficient deuteration methods is great significance for various fields such as organic synthesis, analytical chemistry, medicinal chemistry. Herein, we have developed a dehalogenative strategy using piezoelectric materials catalysts in solid‐phase system under ball‐milling conditions. This non‐spontaneous reaction induced by mechanical force. D 2 O can serve both deuterium source an electron donor the transformation, eliminating need additional stoichiometric exogenous reductants. A series (hetero)aryl iodides be transformed into deuterated products with high incorporation. method not only effectively overcomes existing synthetic challenges but also used labelling drug molecules derivatives. Bioactivity experiments molecule suggest that D‐ipriflavone enhances inhibitory effects on osteoclast differentiation BMDMs vitro .

Language: Английский

Salient Achievements in Synthetic Organic Chemistry Enabled by Mechanochemical Activation DOI
Eusebio Juaristi, C.G. Ávila-Ortíz

Synthesis, Journal Year: 2023, Volume and Issue: 55(16), P. 2439 - 2459

Published: May 3, 2023

Abstract Although known for millennia, it is only recently that mechanochemistry has received serious attention by chemists. Indeed, during the past 15 years an extraordinary number of reports concerning solid-state chemical transformations through grinding and milling techniques have been recorded. This short review discusses circumstances led this renaissance, highlighting present intense interest in so-called green chemistry, enabling capacity to handle insoluble substrates, identification profound influence additives can on mechanochemically activated reactions. The core account focuses salient developments synthetic organic especially amino acid peptide­ mechanosynthesis, successful employment mechanochemical activation combination with asymmetric organocatalysis, promising enzymatic whole cell biocatalysis, remarkable achievement multicomponent selective reactions via complex, multistep reaction pathways, mechanosynthesis representative heterocycles. final section comments some pending tasks area, such as scaling-up processes be practical use industry, requirement easier more efficient control parameters monitoring devices, consequently careful analysis additional procedures a proper understanding phenomena. 1 Introduction 2 Brief History Mechanochemistry 3 Milling Equipment Reaction Parameters 4 Attributes That Propelled Its Present Renaissance 4.1 Enormous Attention Being Presently Paid Sustainable Chemistry 4.2 Reduced Energy Consumption 4.3 Additive-Based 4.4 Handling Insoluble Reactants 4.5 ‘Impossible’ Reactions Are Successful 4.6 Air- Water-Sensitive Reagents Ball 5 Salient Developments Mechanochemical Activation Synthetic Organic 5.1 Amino Acid Peptide Mechanosynthesis 5.2 Asymmetric Synthesis Organocatalysis under Ball-Milling Conditions 5.3 Mechanoenzymology 5.4 Multicomponent Activated 5.5 Heterocycles Modification 6 Future Directions 6.1 Scaling-Up Protocols 6.2 Temperature-Controlled 6.3 Understanding Transformations 6.4 Emerging Techniques 7 Conclusions

Language: Английский

Citations

52

Harvesting the Vibration Energy of CdS for High‐Efficient Piezo‐Photocatalysis Removal of U(VI): Roles of Shape Dependent and Piezoelectric Polarization DOI Creative Commons

Zhimin Dong,

Donglin Gao,

Zifan Li

et al.

Energy & environment materials, Journal Year: 2024, Volume and Issue: 7(5)

Published: Jan. 22, 2024

Piezo‐photocatalysis could coalesce the advantages of mechanical vibration and solar energy perfectly to achieve high‐efficiency catalytic activity. Herein, quintessential piezoelectric material CdS nanowires with different aspect ratios are precisely constructed applied for piezo‐photocatalytic reduction U(VI) first time. The ultrasonic (60 kHz, 100 W) induces potential generate a 0.57 eV A −1 electric field, which is added direction (010) as driving force efficiently separate photogenerated charges. alliance between effect photocatalytic activity endows NW‐3 fastest rate under 5 W LED irradiation, relevant constant (0.042 min ) about 12 53.8 times than that ultrasonication. More importantly, 93.74% be removed from natural uranium mine wastewater. Therefore, this piezo‐photocatalysis system reduces easily separable (UO 2 )O ·2H O(s) provides valuable input disposal applications radioactive wastewater broadens horizons nuclear utilization toward advancement carbon neutrality.

Language: Английский

Citations

20

Low-frequency mechanical energy in the environment for energy production and piezocatalytic degradation of organic pollutants in water: A review DOI
Xiaxia Chen, Jingxue Wang, Zichen Wang

et al.

Journal of Water Process Engineering, Journal Year: 2023, Volume and Issue: 56, P. 104312 - 104312

Published: Sept. 19, 2023

Language: Английский

Citations

26

Depolymerization of Polymethacrylates with Ball-Mill Grinding DOI
Eunsong Jung, Minyoung Cho, Gregory I. Peterson

et al.

Macromolecules, Journal Year: 2024, Volume and Issue: 57(7), P. 3131 - 3137

Published: March 25, 2024

In this report, we demonstrate that polymethacrylates can undergo appreciable depolymerization, with mild conditions and without reactive end groups, using ball-mill grinding (BMG). For instance, the important commercial polymer, poly(methyl methacrylate) (PMMA) underwent up to 41% depolymerization monomer within 8 min of grinding. We explored factors influence conversion found temperature (heating only 43 °C), addition a small amount liquid (μL tert-butyl alcohol), ball number/size be most parameters. also applied method other pendent substituent extent depolymerization. Addition was reverse effects were observed bulk among studied, PMMA had lowest in one highest conversions slurry. Notably, molecular weight residual polymer is remarkably low, ca. 1 kDa, demonstrating excellent degradation performance BMG. Overall, work provides mechanistic insight into reactions under ball-milling represents an step expanding BMG as tool for chemical recycling polymethacrylates.

Language: Английский

Citations

13

Advancements and opportunities in piezo-(photo)catalytic synthesis of value-added chemicals DOI Creative Commons
Weiliang Qi, Yaping Fu,

Enbo Liu

et al.

EES Catalysis, Journal Year: 2024, Volume and Issue: 2(4), P. 884 - 910

Published: Jan. 1, 2024

Achieving value-added transformation of chemicals through green catalytic technology can simultaneously meet the market and environmental protection. This article reviews recent advances in synthesizing using piezo-(photo)catalytic technologies.

Language: Английский

Citations

12

Mechanical‐Force‐Induced Non‐spontaneous Dehalogenative Deuteration of Aromatic Iodides Enabled by Using Piezoelectric Materials as a Redox Catalyst DOI

Ruiling Qu,

Shan Wan, Xuemei Zhang

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(28)

Published: April 30, 2024

Abstract The development of green and efficient deuteration methods is great significance for various fields such as organic synthesis, analytical chemistry, medicinal chemistry. Herein, we have developed a dehalogenative strategy using piezoelectric materials catalysts in solid‐phase system under ball‐milling conditions. This non‐spontaneous reaction induced by mechanical force. D 2 O can serve both deuterium source an electron donor the transformation, eliminating need additional stoichiometric exogenous reductants. A series (hetero)aryl iodides be transformed into deuterated products with high incorporation. method not only effectively overcomes existing synthetic challenges but also used labelling drug molecules derivatives. Bioactivity experiments molecule suggest that D‐ipriflavone enhances inhibitory effects on osteoclast differentiation BMDMs vitro .

Language: Английский

Citations

11

Organic Reactions Enabled by Mechanical Force‐Induced Single Electron Transfer DOI
Ruoxuan Liu,

Xiaochun He,

Tianfen Liu

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(47)

Published: June 18, 2024

Mechanochemical reactions, achieved through milling, grinding, or other mechanical actions, have emerged as a solvent-free alternative to traditional solution-based chemistry. Mechanochemistry not only provides the opportunity eliminate bulk solvent use, reducing waste generation, but also unveils new reaction strategy which enables realization of reactions previously inaccessible in solution. While majority organic facilitated by force traditionally follow two-electron transfer pathways similar their counterparts, field mechanochemically induced single-electron (SET) has witnessed rapid development. This review outlines examples mechanochemical SET process, focusing on reagents that initiate SET, thereby positioning mechanochemistry burgeoning within realm

Language: Английский

Citations

8

Aerobic mechanochemical reversible-deactivation radical polymerization DOI Creative Commons
Haoyang Feng, Zhe Chen,

Lei Li

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: July 22, 2024

Abstract Polymer materials suffer mechano-oxidative deterioration or degradation in the presence of molecular oxygen and mechanical forces. In contrast, aerobic biological activities combined with stimulus promote tissue regeneration repair various organs. A synthetic approach which energy synergistically initiate polymerization will afford similar robustness polymeric materials. Herein, mechanochemical reversible-deactivation radical was developed by design an organic mechano-labile initiator converts into activators response to ball milling, enabling reaction proceed air low-energy input, operative simplicity, avoidance potentially harmful solvents. addition, this not only complements existing methods access well-defined polymers but also has been successfully employed for controlled (meth)acrylates, styrenic monomers solid acrylamides as well synthesis polymer/perovskite hybrids without solvent at room temperature are inaccessible other means.

Language: Английский

Citations

8

Mechanochemical Vicinal Dibromination of Unactivated Alkenes and Alkynes Using Piezoelectric Material as a Redox Catalyst DOI

Fengzhi You,

Xuemei Zhang, Xiaohong Wang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(20), P. 4240 - 4245

Published: May 14, 2024

Mechanoredox chemistry is a rapidly evolving field at the intersection of mechanical forces and chemical reactions. Herein, we have reported vicinal dibromination unsaturated hydrocarbons using piezoelectric material (Li2TiO3) as redox catalyst. Furthermore, reaction can be efficiently scaled up to 10 mmol performed under an air atmosphere room temperature without solvents or external reductants, Li2TiO3 reused multiple times structural change.

Language: Английский

Citations

7

BaTiO3 nanocrystals with tunable exposed {001} polar facets: A high-performance piezocatalyst and piezoelectric regenerative medicine DOI

Jiang Wu,

Hao Ye, Elric Zhang

et al.

Nano Energy, Journal Year: 2024, Volume and Issue: 130, P. 110115 - 110115

Published: Aug. 13, 2024

Language: Английский

Citations

7