Intermolecular Formal [2π + 2σ] Cycloaddition of Enol Silyl Ethers with Bicyclo[1.1.0]butanes Promoted by Lewis Acids DOI
Shijie Zhu, Xue Tian, Shiwu Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(30), P. 6309 - 6313

Published: July 23, 2024

Silyl enol ethers react with bicyclo[1.1.0]butanes (BCBs) through Yb(OTf)

Language: Английский

Enantioselective synthesis of 2-substituted bicyclo[1.1.1]pentanes via sequential asymmetric imine addition of bicyclo[1.1.0]butanes and skeletal editing DOI

Jinteng Che,

Wei‐Yi Ding, Hongbo Zhang

et al.

Nature Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Language: Английский

Citations

2
Silver-mediated formal [4π + 2σ] cycloaddition reactions of bicyclobutanes with nitrile imines: access to 2,3-diazobicyclo[3.1.1]heptenes DOI Creative Commons

Huijuan Liao,

Jianyang Dong,

Xuechen Zhou

et al.

Chemical Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We disclose a method for silver-enabled formal [4π + 2 σ ] cycloaddition reactions between bicyclobutanes and nitrile imines (generated from hydrazonyl chlorides) to furnish diverse array of 2,3-diazo-BCHepes.

Language: Английский

Citations

2
Lewis acid-catalyzed diastereoselective formal ene reaction of thioindolinones/thiolactams with bicyclobutanes DOI Creative Commons
Avishek Guin,

Shiksha Deswal,

Mahesh Singh Harariya

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(31), P. 12473 - 12479

Published: Jan. 1, 2024

Bicyclo[1.1.0]butanes (BCBs), featuring two fused cyclopropane rings, have found widespread application in organic synthesis. Their versatile reactivity towards radicals, nucleophiles, cations, and carbenes makes them suitable for various reactions, including ring-opening annulation strategies. Despite this versatility, their potential as enophiles an ene reaction remains underexplored. Considering given the challenges of achieving diastereoselectivity reactions BCBs, herein, we present a unique method utilizing BCBs mild diastereoselective Sc(OTf)

Language: Английский

Citations

12
Lewis Acid‐Catalyzed Unusual (4+3) Annulation of para‐Quinone Methides with Bicyclobutanes: Access to Oxabicyclo[4.1.1] octanes DOI

Shiksha Deswal,

Avishek Guin, Akkattu T. Biju

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(48)

Published: Aug. 22, 2024

Over the past few years, there has been a surge of interest in chemistry bicyclobutanes (BCBs). Although BCBs have used to synthesize bicyclo[2.1.1]hexanes and bicyclo[3.1.1]heptanes, synthesis bicyclo[4.1.1]octanes remained elusive. Herein, we report first Lewis acid-catalyzed unexpected (4+3) annulation para-quinonemethides (p-QMs) with allowing oxabicyclo[4.1.1]octanes proceeding under mild conditions. With 5 mol % Bi(OTf)

Language: Английский

Citations

12
Intermolecular Formal [2π + 2σ] Cycloaddition of Enol Silyl Ethers with Bicyclo[1.1.0]butanes Promoted by Lewis Acids DOI
Shijie Zhu, Xue Tian, Shiwu Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(30), P. 6309 - 6313

Published: July 23, 2024

Silyl enol ethers react with bicyclo[1.1.0]butanes (BCBs) through Yb(OTf)

Language: Английский

Citations

11