European Polymer Journal, Journal Year: 2024, Volume and Issue: unknown, P. 113518 - 113518
Published: Oct. 1, 2024
Language: Английский
Macromolecules, Journal Year: 2025, Volume and Issue: 58(3), P. 1621 - 1629
Published: Jan. 31, 2025
Sulfone bonding refers to dipole–dipole interactions between sulfone groups, which have been long overlooked. Herein, was employed for the first time as driving force self-assembly of block copolymers via a polymerization-induced sulfone-bond-driven (PI-SDSA) strategy. The presence in sulfone-functionalized monomer confirmed by scanning tunneling microscopy break junction measurements at single-molecule level. Successful PI-SDSA achieved toluene, and polymerization kinetics polymerization-enhanced force. demonstrated possess peculiar monomer/solvent library successful series sulfone-containing monomers solvents with varying dipole moments. as-prepared polymer assemblies manifested unique salt-responsiveness because competitive ion–dipole ions enabling salt-responsive payload release. use has provided new perspective both will inspire design stimuli-responsive supramolecular materials.
Language: Английский
Citations
2
Nature Synthesis, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 10, 2025
Language: Английский
Citations
1
Macromolecular Rapid Communications, Journal Year: 2024, Volume and Issue: 45(14)
Published: April 25, 2024
Abstract Protein–polymer conjugates and polymeric nanomaterials hold great promise in many applications including biomaterials, medicine, or nanoelectronics. In this work, the first polymerization‐induced self‐assembly (PISA) approach performed aqueous medium enabling protein–polymer nanoparticles entirely composed of amino acids is presented by using ring‐opening polymerization (ROP). It indeed shown that (ROPISA) can be used with protein peptidic macroinitiators without prior chemical modification afford simple preparation protein‐like property, for example, to implement biomimetic thermoresponsivity drug delivery.
Language: Английский
Citations
6
Polymer Chemistry, Journal Year: 2024, Volume and Issue: 15(16), P. 1577 - 1590
Published: Jan. 1, 2024
This review summarizes the recent advances in PISA for fabrication of polymer assemblies-based nanostructured hydrogels, including colloidal multiphase and micelle-crosslinked hydrogels.
Language: Английский
Citations
4
Polymers, Journal Year: 2024, Volume and Issue: 16(15), P. 2097 - 2097
Published: July 23, 2024
Polymer self-assembly can prepare various shapes and sizes of pores, making it widely used. The complexity diversity biomolecules make them a unique class building blocks for precise assembly. They are particularly suitable the new generation biomaterials integrated with life systems as they possess inherent characteristics such accurate identification, self-organization, adaptability. Therefore, many excellent methods developed have led to practical results. At same time, development advanced science technology has also expanded application scope synthetic polymers. By utilizing this technology, materials properties be prepared applied in field tissue engineering. Nanomaterials transparent conductive fields electronic displays smart glass. Multi-dimensional, controllable, multi-level between nanostructures been achieved through quantitative control polymer dosage combination, chemical modification, composite methods. Here, we list classic applications natural- artificially synthesized biomedicine materials, introduce cutting-edge technologies involved these applications, discuss in-depth advantages, disadvantages, future directions each type self-assembly.
Language: Английский
Citations
4
ACS Macro Letters, Journal Year: 2024, Volume and Issue: 13(8), P. 1022 - 1030
Published: July 29, 2024
Herein, an ω,ω-macromolecular chain transfer monomer (macro-CTM) containing a RAFT (reversible addition-fragmentation transfer) group and methacryloyl was synthesized used to mediate photoinitiated dispersion polymerization of hydroxypropyl methacrylate (HPMA) in water. The macro-CTM undergoes self-condensing vinyl (SCVP) mechanism under conditions, leading the formation amphiphilic branched block copolymers assemblies. Compared with solution polymerization, it found that SCVP process promoted conditions. Morphologies copolymer assemblies could be controlled by varying concentration [HPMA]/[macro-CTM] ratio. vesicles as seeds for seeded emulsion framboidal were successfully obtained. Finally, degrees branching further using binary mixture linear macro-RAFT agent or small molecule CTM. We believe this study not only provides versatile strategy preparation but also offers important insights into polymer synthesis via heterogeneous polymerization.
Language: Английский
Citations
4
RSC Advances, Journal Year: 2025, Volume and Issue: 15(6), P. 4693 - 4700
Published: Jan. 1, 2025
Factors like nature of the m-RAFT, oxygen, and temperature are crucial in chemical degradation, which functionalizes polymersomes, allowing them to manifest Phoenix dynamics, whereby they exhibit growth-implosion cycles population growth.
Language: Английский
Citations
0
Macromolecular Rapid Communications, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 2, 2025
Abstract Compared with other sequence structure polymers, alternating polymers usually have several unique properties, but their properties are more sensitive to changes in structure. By investigating the relationship between and of polymer chains, desired can likely be synthesized. In this study, a series copolymers 1,1‐diphenylethylene (DPE) derivatives styrene derivatives, which exhibit nontraditional intrinsic luminescence (NTIL), synthesized using living anionic polymerization. changing bridge plane DPE substituent groups rigid chain containing derivative large steric hindrance is altered, change observed by altered fluorescence properties. Based on results from experimental tests theoretical simulations, structures higher emission intensities; moreover, balance electronic effects substituents intensities, chains that too cause decrease intensities. Thus, influence NTIL cannot disregarded.
Language: Английский
Citations
0
Advanced Science, Journal Year: 2025, Volume and Issue: unknown
Published: March 26, 2025
Metastasis is the leading cause of death in patients with lung cancer. Multidisciplinary comprehensive treatments (MDT), including surgery, chemotherapy, radiotherapy, gene-targeted therapy, immunotherapy, antibody-drug conjugate (ADC), natural products, etc., have been currently used for cancer metastasis. The MDT model has shown promising efficacy against metastasis clinical practice. However, these therapies some limitations, such as unusual toxic side effects, drug resistance, limited indications, and high costs. Therefore, emerging technological platforms are imperative to overcome bottlenecks. Nanomedicine can be prepare efficient delivery systems owing its good biocompatibility, targeting, responsive release, multidrug codelivery plays an important role synergistic antimetastasis because optical, acoustic, electrical, thermal, magnetic functions. This review analyses limitations model, briefly outlines advantages nanotechnology, introduces nanodrug systems, summarizes nanostrategies based on invasion-metastasis cascade process, provides a summary prospects challenges translation nanomedicines.
Language: Английский
Citations
0
Polymers, Journal Year: 2024, Volume and Issue: 16(10), P. 1408 - 1408
Published: May 15, 2024
Polymerization-induced self-assembly (PISA) is a powerful and versatile technique for producing colloidal dispersions of block copolymer particles with desired morphologies. Currently, PISA can be carried out in various media, over wide range temperatures, using different mechanisms. This method enables the production biodegradable objects functionalities stimuli sensitivity. Consequently, offers broad spectrum potential commercial applications. The aim this review to provide an overview current state rational synthesis diverse morphologies techniques discussion begins examination main thermodynamic, kinetic, structural aspects micellization, followed by exploration key principles formation gradient copolymers. also delves into mechanisms implementation governing particle morphology. Finally, future developments are considered.
Language: Английский
Citations
2