Altering the mechanical properties of self-assembled filaments through engineering of EspA bacterial protein DOI Creative Commons

Moran Elias-Mordechai,

May Morhaim,

Maya Georgia Pelah

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 30, P. 101414 - 101414

Published: Dec. 18, 2024

Language: Английский

Insights Into Cold Atmospheric Plasma Triggered Self‐Assembly of Keratin Protein DOI Open Access
Priya Bhatt, Kamatchi Sankaranarayanan

Plasma Processes and Polymers, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

ABSTRACT Cold Atmospheric Plasma (CAP) is a novel method for biomaterial fabrication, inducing physicochemical changes in biomolecules. Keratin, an industrial waste product valued its biocompatibility and biodegradability, formed self‐assembled structures under CAP treatment, as revealed by SEM. Zeta analysis showed increased surface charge, while TGA XRD confirmed enhanced crystallinity with sharp‐edged nanocrystalline structures. Unique self‐assembly behaviors were observed un‐dialyzed dialyzed keratin. modified keratin's through reactive oxygen nitrogen species (RONS), physical without altering chemical structure or native conformation. This highlights CAP's potential to tailor keratin properties specific applications.

Language: Английский

Citations

1
Fundamental and Application of Co-assembly of Peptides and Proteins: Experiment and Computation DOI Creative Commons

Newton A. Ihoeghian,

Qing Shao

Supramolecular Materials, Journal Year: 2025, Volume and Issue: unknown, P. 100103 - 100103

Published: April 1, 2025

Language: Английский

Citations

1
Self-Assembly of Polymers and Their Applications in the Fields of Biomedicine and Materials DOI Open Access
Lina Hu, Shujing Zhou, Xiumei Zhang

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(15), P. 2097 - 2097

Published: July 23, 2024

Polymer self-assembly can prepare various shapes and sizes of pores, making it widely used. The complexity diversity biomolecules make them a unique class building blocks for precise assembly. They are particularly suitable the new generation biomaterials integrated with life systems as they possess inherent characteristics such accurate identification, self-organization, adaptability. Therefore, many excellent methods developed have led to practical results. At same time, development advanced science technology has also expanded application scope synthetic polymers. By utilizing this technology, materials properties be prepared applied in field tissue engineering. Nanomaterials transparent conductive fields electronic displays smart glass. Multi-dimensional, controllable, multi-level between nanostructures been achieved through quantitative control polymer dosage combination, chemical modification, composite methods. Here, we list classic applications natural- artificially synthesized biomedicine materials, introduce cutting-edge technologies involved these applications, discuss in-depth advantages, disadvantages, future directions each type self-assembly.

Language: Английский

Citations

6
Design and Characterization of Peptide-Based Self-Assembling Microgel for Encapsulation of Sesaminol DOI Creative Commons
Jinhong Gao,

Heng Du,

Zhenhong Zhang

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(6), P. 971 - 971

Published: March 12, 2025

Sesaminol is a natural functional compound of sesame with low bioaccessibility due to its high crystallinity. Here, peptide-based self-assembly microgel was constructed encapsulate sesaminol, reducing crystallinity and improving bioaccessibility. In this contribution, the peptide AcNH-Leu-Tyr-Tyr-CONH2 (LYY) shown form mesoporous three-dimensional (3D) through microstructure characterization. Various characterization methods revealed that LYY self-assembled β-folds random coils, primary intermolecular interactions arose from hydrogen bonding π-π stacking effect. Subsequently, sesaminol encapsulated within co-assembly. The maximum encapsulation efficiency 80.8 ± 0.9%, mainly in nanoparticles by morphology XRD results indicated primarily existed an amorphous state following encapsulation. cumulative release had sustained effect system. Its antioxidant levels were increased. Molecular docking main between structure interactions. Establishing provides valuable data theoretical support for research processing industry.

Language: Английский

Citations

0
Unravelling the amyloid aggregation mechanism of the sweet protein Monellin: Insights from circular permutated mutants DOI

Rosanna Lucignano,

Andrea Bologna,

Simona Gramazio

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142239 - 142239

Published: March 1, 2025

Language: Английский

Citations

0
Self‐assembly of Tyrosine Scaffolds in Aqueous Media: Complex Molecular Architectures from Simple Building Blocks DOI

Dineshkumar Bharathidasan,

Chandan Maity

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

Abstract Mimicking natural systems, self‐assembly has been employed for constructing highly stable and well‐ordered supramolecular structures. Amino acids are frequently used as building blocks in the process due to their advantageous characteristics including easy availability, functionalization, tunable mechanical property, biodegradability. In situ generation of active obtain complex materials via enhanced application biomedical fields bio‐imaging, therapeutics. Single amino acid small building‐block can provide artificial with unique properties. this review, we summarize tyrosine‐derivatives single acid‐based providing assemblies perspectives on potential impact. Finally, discuss ongoing challenges future research.

Language: Английский

Citations

0
Machine-learning-guided identification of protein secondary structures using spectral and structural descriptors DOI Creative Commons

Ziqi Wang,

Kenry Kenry

Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We demonstrated the implementation of a machine-learning-mediated approach to identify secondary structures proteins based on different spectral and structural descriptors.

Language: Английский

Citations

0
Chitin nanofibers: recent advances in preparation and applications in biomedical and beyond DOI Creative Commons
Md Ariful Islam, M. Nahid Hasan, Md. Sadik Hussain Evan

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(19), P. 14655 - 14690

Published: Jan. 1, 2025

Chitin and chitosan-based nanofibers (ChNFs) from renewable sources are promising biomaterials. This review compares ChNF extraction/synthesis methods, detailing challenges opportunities. Biomedical environmental applications emphasized.

Language: Английский

Citations

0
Self-assembly of anisotropic nano-building-blocks DOI Creative Commons

Cuiling Hou,

Zhenhua Chen, Z. Chang

et al.

Next Nanotechnology, Journal Year: 2025, Volume and Issue: 8, P. 100185 - 100185

Published: Jan. 1, 2025

Language: Английский

Citations

0
Deprotonation-Induced Structural Evolution in the Self-Assembled Submonolayer of Heptaazaphenalene-Tribenzoic Acid on Au(111) DOI
Zhaokun Wang, Haiwei Wang, Shixun Dai

et al.

Langmuir, Journal Year: 2025, Volume and Issue: unknown

Published: June 4, 2025

We report the thermally induced self-assembly evolution of 4,4',4″-(1,3,4,6,7,9,9b-heptaazaphenalene-2,5,8-triyl) tris-benzoic acid (HTBA) molecules on Au(111) at submonolayer coverage using scanning tunneling microscopy (STM). STM imaging reveals a structural transformation from honeycomb network stabilized by hydrogen bonds room temperature to step-like phase with partial deprotonation 320 K and finally chiral pinwheel formed fully deprotonated 380 K. The features coexisting enantiomorphic domains dense hexagonal cavities. These results demonstrate pivotal role in controlling molecular offer insights for designing responsive nanostructures metal surfaces.

Language: Английский

Citations

0