Metal-free Decarboxylative Oxygenation of α-Amino Acids to Amide Compounds via Photoredox Catalysis DOI
Rui Zhu,

Yaxin Wang,

Minshu Cui

et al.

Applied Catalysis A General, Journal Year: 2024, Volume and Issue: unknown, P. 120084 - 120084

Published: Dec. 1, 2024

Language: Английский

Continuous Flow Decarboxylative Monofluoroalkylation Enabled by Photoredox Catalysis DOI Creative Commons

F Pasca,

Yuri Gelato,

Michael Andresini

et al.

JACS Au, Journal Year: 2025, Volume and Issue: 5(2), P. 684 - 692

Published: Feb. 2, 2025

Herein, we report a scalable and mild strategy for the monofluoroalkylation of wide array Giese acceptors via visible-light-mediated photoredox catalysis in continuous flow. The use flow technology significantly enhances productivity scalability, whereas mildness conditions functional group tolerance are ensured by leveraging 4CzIPN, transition-metal-free organic photocatalyst. Structurally diverse secondary tertiary monofluoroalkyl radicals can thus be accessed from readily available α-monofluorocarboxylic acids. Given reaction conditions, this protocol is also amenable to late-stage functionalization biologically relevant molecules such as menthol, amantadine, bepotastine, estrone derivatives, rendering it suitable application drug discovery programs, which introduction fluorinated fragments highly sought after. This method was extended enable reductive multicomponent radical-polar crossover transformation rapidly increase complexity assembled architectures single synthetic operation.

Language: Английский

Citations

3
Photocatalytic C−C bond formation and cleavage reactions based on graphitic carbon nitride semiconductor materials DOI
Wenjie Zhang,

Zeyao Liang,

Xiaoquan Yao

et al.

Tetrahedron, Journal Year: 2025, Volume and Issue: unknown, P. 134651 - 134651

Published: April 1, 2025

Language: Английский

Citations

0
One Step Synthesis of Carbon Nitride/Carbon Nanotube Composite Nanomaterials Modified Electrode for Sensitive Electrochemical Detection of Bisphenol A DOI Creative Commons
Yanhua Sun, Mang Niu, Yang Bai

et al.

Journal of The Electrochemical Society, Journal Year: 2025, Volume and Issue: 172(2), P. 027503 - 027503

Published: Jan. 29, 2025

In this work, RCN/WCNTs nanocomposites were synthesized using a one-step method and characterized SEM, XPS, FTIR. An electrochemical sensor capable of sensitive rapid detection BPA was developed by modifying on glassy carbon electrode. The exhibited excellent response to in 0.2 M PBS (pH 7.0) under optimal selection conditions. linear range the 0.01–43 μM, limit (S/N = 3) 0.0017 μM. addition, good immunity, stability reproducibility. And it applied real samples.

Language: Английский

Citations

0
Metal-free Decarboxylative Oxygenation of α-Amino Acids to Amide Compounds via Photoredox Catalysis DOI
Rui Zhu,

Yaxin Wang,

Minshu Cui

et al.

Applied Catalysis A General, Journal Year: 2024, Volume and Issue: unknown, P. 120084 - 120084

Published: Dec. 1, 2024

Language: Английский

Citations

1