A Tandem Catalysis for Isoindolinone Synthesis over Single‐atom Pd/TiO2 Catalyst DOI
Jin Xie, Jianian Cheng,

Junbao Peng

et al.

Angewandte Chemie, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Abstract Developing an efficient strategy to replace the conventional synthesis method for producing isoindolinone (IIO) scaffold, a crucial structural motif constructing pharmaceutical molecules, remains be great challenge. Herein, single‐atom Pd/TiO 2 tandem catalysis has been developed IIO scaffold by using readily available phthalic anhydride (PA), ammonia, and H . The catalyst demonstrates superior catalytic performance, achieving PA conversion of 99 %, selectivity 91 turnover frequency (TOF) up 4807 h −1 This exceptional performance can attributed between TiO support Pd. efficiently catalyzes with ammonia form phthalimide (PAM), subsequently transformed into over through reaction PAM NH 3 spillover hydrogen species derived from Notably, functions not only as reactant but also promoter accelerate reduction amides combined catalyst. provides promising platform molecules.

Language: Английский

Modulating the Electronic Properties of Single Ni Atom Catalyst via First‐Shell Coordination Engineering to Boost Electrocatalytic Flue Gas CO2 Reduction DOI Open Access
Zhiyuan Wang, Zhen Chen, Xin Du

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 10, 2025

Abstract Electrochemical converting CO 2 to via single atom catalyst is an effective strategy for reducing concentration in the atmosphere and achieving a carbon‐neutral cycle. However, relatively low industrial processes large energy barriers activating severely obstruct actual application. Reasonably modulating coordination shell of active center enhance activity catalysts. Herein, well‐designed single‐atom electrocatalyst Ni‐N 3 S 1 developed large‐scale synthesis strategy. The constructed S‐C exhibits superior catalytic than 4 ‐C conversion H‐type cells, industrial‐level current density with excellent durability at wide pH range can be achieved gas‐diffusion flow cells. Experimental results functional theory (DFT) calculation demonstrate that introducing electronegative significantly regulate electronic structure site, promoting adsorption capacity decreasing barrier *COOH formation, thus larger size flexibility sulfur mitigate nickel agglomeration stability catalyst. This work provides designing highly catalysts electrocatalysis reactive sites.

Language: Английский

Citations

2
Strong electronic metal-support interactions for enhanced hydroformylation activity and stability over Rh single-atom catalysts through phosphorus doping DOI
Bo Fu,

Ping Ma,

Xiaoqi Ding

et al.

JUSTC, Journal Year: 2025, Volume and Issue: 55, P. 1 - 1

Published: Jan. 1, 2025

Language: Английский

Citations

0
A Tandem Catalysis for Isoindolinone Synthesis over Single‐atom Pd/TiO2 Catalyst DOI
Jin Xie, Jianian Cheng,

Junbao Peng

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Abstract Developing an efficient strategy to replace the conventional synthesis method for producing isoindolinone (IIO) scaffold, a crucial structural motif constructing pharmaceutical molecules, remains be great challenge. Herein, single‐atom Pd/TiO 2 tandem catalysis has been developed IIO scaffold by using readily available phthalic anhydride (PA), ammonia, and H . The catalyst demonstrates superior catalytic performance, achieving PA conversion of 99 %, selectivity 91 turnover frequency (TOF) up 4807 h −1 This exceptional performance can attributed between TiO support Pd. efficiently catalyzes with ammonia form phthalimide (PAM), subsequently transformed into over through reaction PAM NH 3 spillover hydrogen species derived from Notably, functions not only as reactant but also promoter accelerate reduction amides combined catalyst. provides promising platform molecules.

Language: Английский

Citations

3
A Tandem Catalysis for Isoindolinone Synthesis over Single‐atom Pd/TiO2 Catalyst DOI
Jin Xie, Jianian Cheng,

Junbao Peng

et al.

Angewandte Chemie, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Abstract Developing an efficient strategy to replace the conventional synthesis method for producing isoindolinone (IIO) scaffold, a crucial structural motif constructing pharmaceutical molecules, remains be great challenge. Herein, single‐atom Pd/TiO 2 tandem catalysis has been developed IIO scaffold by using readily available phthalic anhydride (PA), ammonia, and H . The catalyst demonstrates superior catalytic performance, achieving PA conversion of 99 %, selectivity 91 turnover frequency (TOF) up 4807 h −1 This exceptional performance can attributed between TiO support Pd. efficiently catalyzes with ammonia form phthalimide (PAM), subsequently transformed into over through reaction PAM NH 3 spillover hydrogen species derived from Notably, functions not only as reactant but also promoter accelerate reduction amides combined catalyst. provides promising platform molecules.

Language: Английский

Citations

0