32nd Annual GP2A Medicinal Chemistry Conference DOI Creative Commons
Jean‐Jacques Hélesbeux, Florence O. McCarthy, Maria Manuel Silva

et al.

Drugs and Drug Candidates, Journal Year: 2025, Volume and Issue: 4(1), P. 2 - 2

Published: Jan. 9, 2025

The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held its 32nd annual conference August 2024 at University Coimbra, Portugal. There were 8 keynote presentations, 12 early career researcher oral and 34 poster presentations. Four awards delivered, two best communications

Language: Английский

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System DOI Creative Commons

Alessio Colleoni,

Giulia Galli, Clelia Dallanoce

et al.

Medicinal Research Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: March 23, 2025

ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, inflammation. Conventional cholinergic drugs generally suffer from poor selectivity temporal precision, leading to undesired effects limited therapeutic efficacy. Photopharmacology aims overcome limitations of traditional using photocleavable or photoswitchable ligands spatiotemporal patterns illumination. Spanning muscarinic nicotinic modulators cholinesterase inhibitors, this review explores development application light‐activated compounds tools for unraveling signaling physiological pathological contexts, while also paving way innovative phototherapeutic approaches.

Language: Английский

Citations

0

32nd Annual GP2A Medicinal Chemistry Conference DOI Creative Commons
Jean‐Jacques Hélesbeux, Florence O. McCarthy, Maria Manuel Silva

et al.

Drugs and Drug Candidates, Journal Year: 2025, Volume and Issue: 4(1), P. 2 - 2

Published: Jan. 9, 2025

The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held its 32nd annual conference August 2024 at University Coimbra, Portugal. There were 8 keynote presentations, 12 early career researcher oral and 34 poster presentations. Four awards delivered, two best communications

Language: Английский

Citations

0