Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

An anaerobic 1,2-/1,3-hydroxytrifluoromethylation of unactivated alkenes is described. This reaction proceeds in mild and environmentally friendly conditions without photocatalyst metal catalyst, allowing access to a wide range β- γ-trifluoromethyl alcohols. Preliminary mechanistic investigations indicate that the accomplishment this protocol relies on dual functionality photoexcited triplet nitroarenes, which serve as oxygen atom source enable single-electron transfer (SET) process with CF

Language: Английский