Synthesis and Antibacterial Properties of New Quinazoline Analogs Catalyzed by Chloroacetic Acid–Immobilized Nanocobaltferrite

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(2)

Published: Jan. 1, 2025

ABSTRACT In this research, an effective procedure for the one‐pot construction of new quinazoline analogs using chloroacetic acid – immobolized nanocobaltferrite (nano‐CoFe 2 O 4 @SiO @CPTES‐[(Ph₂PCH₂)₂‐CH CO H] 2+ 2Cl − ) as efficient novel magnetic nanocatalyst under ultrasound irradiation at 80°C was presented. Chloroacetic acid–immobilized nanocobferrite characterized by FT‐IR, XRD, FE‐SEM, TEM, EDX, TGA, VSM, and ICP‐mass analyses. Furthermore, could be comfortably isolated via attraction recycled least five times without remarkable loss its catalytic activity. Additionally, in protocol, were screened their antibacterial activity against Pseudomonas aeruginosa Staphylococcus aureus . The results showed that quinazolines 4a , 4b 4c 4d 4g had good toward

Language: Английский

Ursolic Acid‐Bonded Magnetic Nanoparticles Catalyzed the One‐Pot Synthesis of New Hexahydroquinoline‐3‐carboxamides

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(10)

Published: March 1, 2025

Abstract In this research, we present an effective method for synthesizing new derivatives of hexahydroquinoline‐3‐carboxamides through a one‐pot synthesis using formylarylsulfonates, dimedone or 1,3‐cyclohexanedione, acetoacetanilide, and ammonium acetate in high to excellent yield EtOH at reflux conditions. This utilizes ursolic acid (UA)‐bonded magnetic nanoparticles (nano‐Fe 3 O 4 @UA) as catalyst. The offers several advantages, including yield, short reaction time, simplicity, making it attractive efficient option the emerging field hexahydroquinolines synthesis.

Language: Английский

An Effective Method for the Synthesis of New Bis(indole)methane Analogs Using Rosmarinic Acid‐Supported Magnetic Nanoparticles (Nano‐Fe₃O₄@RA)

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(39)

Published: Oct. 1, 2024

Abstract This research presents an effective method for synthesizing new derivatives of bis(indole)methane using rosmarinic acid supported magnetic nanoparticles (nano‐Fe 3 O 4 @RA) as a catalyst. The reaction offers numerous advantages, such high yield, catalyst reusability, short time, product purification without column chromatography, and simple procedure. These factors make it attractive efficient option in the field construction.

Language: Английский