Journal of Polymer Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 10, 2025
ABSTRACT
Skin
defects
caused
by
injuries
such
as
burns
that
exceed
a
certain
diameter
no
longer
heal
spontaneously
and
require
more
complex
interventions.
Hydrogels
have
received
special
attention
due
to
their
unique
ability
block
the
penetration
of
bacteria
into
wounds
they
can
absorb
contaminated
exudates
exhibit
high
degree
flexibility.
This
study
is
focused
on
preparation
characterization
novel
antibacterial
biocomposite
hydrogels
based
two
carbohydrates,
alginate
hyaluronic
acid
(HA),
with
immobilized
ZnO
NPs
curcumin‐loaded
electrospun
nanofibers
improve
efficacy
wound
healing
process.
The
hydrogel
matrix
was
obtained
after
crosslinking
HA
in
presence
DMT‐MM
activator.
were
physicochemically
characterized
FT‐IR,
scanning
electron
microscopy
(SEM),
UV–Vis
spectroscopy,
swelling
also
investigated.
It
appeared
behavior
influenced
amount
nanofibers.
Biodegradability,
hemolysis,
cell
viability,
antimicrobial,
vitro
irritability
tests
carried
out
assess
biological
properties.
results
highlighted
these
are
biodegradable,
hemocompatible,
non‐cytotoxic,
non‐irritating
good
antimicrobial
activity.
Based
results,
materials
might
be
interesting
candidates
for
treatment.
Biopolymers,
Journal Year:
2025,
Volume and Issue:
116(2)
Published: March 1, 2025
ABSTRACT
This
comprehensive
review
explores
the
potential
of
plant‐
and
biopolymeric‐based
antibacterials
as
innovative
therapeutic
agents
for
infectious
skin
wound
healing.
By
researching
antibacterial
properties
various
plants,
highlights
their
application
in
tissue
engineering.
Beyond
reviewing
plant
extracts,
article
delves
into
limitations
these
natural
compounds
face,
such
hydrophilicity,
drug
release
rates,
cell
attachment,
scaffold
stability
when
integrated
engineering
constructs.
The
also
emphasizes
role
biopolymeric
materials,
hydrogel
optimization,
crosslinkers
to
improve
performance.
provides
a
roadmap
future
research
by
addressing
critical
factors
construction.
In
end,
it
aims
guide
development
more
effective
dressings
scaffolds,
combining
power
plants
with
advanced
materials
enhanced
healing
therapies.
Journal of Polymer Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 10, 2025
ABSTRACT
Skin
defects
caused
by
injuries
such
as
burns
that
exceed
a
certain
diameter
no
longer
heal
spontaneously
and
require
more
complex
interventions.
Hydrogels
have
received
special
attention
due
to
their
unique
ability
block
the
penetration
of
bacteria
into
wounds
they
can
absorb
contaminated
exudates
exhibit
high
degree
flexibility.
This
study
is
focused
on
preparation
characterization
novel
antibacterial
biocomposite
hydrogels
based
two
carbohydrates,
alginate
hyaluronic
acid
(HA),
with
immobilized
ZnO
NPs
curcumin‐loaded
electrospun
nanofibers
improve
efficacy
wound
healing
process.
The
hydrogel
matrix
was
obtained
after
crosslinking
HA
in
presence
DMT‐MM
activator.
were
physicochemically
characterized
FT‐IR,
scanning
electron
microscopy
(SEM),
UV–Vis
spectroscopy,
swelling
also
investigated.
It
appeared
behavior
influenced
amount
nanofibers.
Biodegradability,
hemolysis,
cell
viability,
antimicrobial,
vitro
irritability
tests
carried
out
assess
biological
properties.
results
highlighted
these
are
biodegradable,
hemocompatible,
non‐cytotoxic,
non‐irritating
good
antimicrobial
activity.
Based
results,
materials
might
be
interesting
candidates
for
treatment.
