In vitro α-amylase and α-glucosidase inhibition study of dihydropyrimidinones synthesized via one-pot Biginelli reaction in the presence of a green catalyst

Bioorganic Chemistry, Journal Year: 2024, Volume and Issue: 143, P. 107085 - 107085

Published: Jan. 3, 2024

Language: Английский

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A comprehensive review on the rational design of MOF-based heterogeneous catalysts for the classic Biginelli reaction

Polyhedron, Journal Year: 2025, Volume and Issue: 277, P. 117570 - 117570

Published: April 28, 2025

Language: Английский

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Pyrimidines: A New Versatile Molecule in the Drug Development Field, Scope, and Future Aspects

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(10), P. 1258 - 1258

Published: Sept. 24, 2024

Pyrimidine is a moiety that occurs in living organisms and has variety of significant biological properties pharmacology. Due to the easy handling synthesis, easily available precursor, less duration for reaction, not many technical skills are needed. All these factors attract chemists focus more on pyrimidines. Apart from synthesis applications pyrimidines, medicinal have gathered explore pyrimidine scaffolds due their interesting targeting various binding sites. This review delves into diverse activities compounds derived during year 2024. We attempted growing significance derivatives provide new path designing potent molecules.

Language: Английский

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Antioxidant and cytotoxic activities of 2-oxo-1,2,3,4-tetrahydropyrimidines

Results in Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 101891 - 101891

Published: Nov. 1, 2024

Language: Английский

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