Discovery of novel pyrrolo[2,3-d]pyrimidine derivatives as anticancer agents: virtual screening and molecular dynamic studies DOI
Sunny Dhiman, Swati Gupta, Sushil K. Kashaw

et al.

SAR and QSAR in environmental research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 33

Published: Nov. 28, 2024

CDK/Cyclins are dysregulated in several human cancers. Recent studies showed inhibition of CDK4/6 was responsible for controlling cell cycle progression and cancer growth. In the present study, atom-based field-based 3D-QSAR, virtual screening, molecular docking dynamics were done development novel pyrrolo[2,3-d]pyrimidine (P2P) derivatives as anticancer agents. The developed models good

Language: Английский

Discovery of novel pyrrolo[2,3-d]pyrimidine derivatives as anticancer agents: virtual screening and molecular dynamic studies DOI
Sunny Dhiman, Swati Gupta, Sushil K. Kashaw

et al.

SAR and QSAR in environmental research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 33

Published: Nov. 28, 2024

CDK/Cyclins are dysregulated in several human cancers. Recent studies showed inhibition of CDK4/6 was responsible for controlling cell cycle progression and cancer growth. In the present study, atom-based field-based 3D-QSAR, virtual screening, molecular docking dynamics were done development novel pyrrolo[2,3-d]pyrimidine (P2P) derivatives as anticancer agents. The developed models good

Language: Английский

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