Cited by Click Reaction of Calcium Carbide-Derived Acetylene as a Direct Way to Chromophore- and Fluorophore-Substituted 1,2,3-Triazoles

Calcium carbide: Highly potent solid reagent for the construction of heterocycles DOI

Maria S. Ledovskaya, Vladimir V. Voronin

Tetrahedron, Journal Year: 2023, Volume and Issue: 149, P. 133720 - 133720

Published: Nov. 1, 2023

Language: Английский

Citations

Vinylation of Alcohols, Thiols, and Nitrogen Compounds Using a Stoichiometric Amount of In Situ Generated Acetylene DOI

Maria S. Ledovskaya, Vladimir V. Voronin,

А.А. Reznichenko

et al.

Organics, Journal Year: 2025, Volume and Issue: 6(1), P. 5 - 5

Published: Feb. 8, 2025

In this work, we developed a highly efficient and versatile environmentally benign methodology for the vinylation of broad scope substances, including alcohols, thiols, nitrogen compounds. The key advantage proposed method is use calcium carbide as robust acetylene source in stoichiometric ratio to substrates. Lacking requirement excess, protocol safe, economic, limits waste production. procedure allows large variety O-,S-,N-vinyl compounds be synthesized up quantitative yields. Our scalable, allowing us obtain vinyl derivatives Gram-scale quantities. We also demonstrated significant synthetic value our approach by performing label-economic synthesis 13C2-labeled using carbide-13C2. well-optimized process, conversion Ca13C2 reached 89%.

Language: Английский

Citations

Synthesis of Spirocyclic Phthalans via Ru-Catalyzed [2 + 2 + 2] Cycloaddition of 1,6-Diynes with Ex-Situ Generated Acetylene DOI

Yoshihiko Yamamoto,

Kenichi Yoshimura,

Takeshi Yasui

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Spirocyclic motifs are attracting increasing attention owing to their three-dimensional geometries that endow bioactive molecules with superior physical and biological properties. We developed an efficient method for constructing spirocyclic phthalans via the Ru-catalyzed [2 + 2 2] cycloaddition of cycloalkanone-derived 1,6-diynes acetylene gas ex-situ-generated from calcium carbide H2O.

Language: Английский

Citations

The Use of Calcium Carbide for Cyclopentenone Ring Construction DOI

Maria S. Ledovskaya, Vladimir V. Voronin

Russian Journal of General Chemistry, Journal Year: 2024, Volume and Issue: 94(1), P. 45 - 48

Published: Jan. 1, 2024

Language: Английский

Citations

Synthesis of 3-Chloro-6-(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)pyridazine and Its Deuterated Analogue DOI

Maria S. Ledovskaya, Vladimir V. Voronin

Russian Journal of General Chemistry, Journal Year: 2024, Volume and Issue: 94(11), P. 2833 - 2840

Published: Nov. 1, 2024