Heterogeneity of tumor biophysical properties and their potential role as prognostic markers DOI Creative Commons
Anja Madleine Markl,

Daniel Nieder,

Diana Isabel Sandoval-Bojorquez

et al.

Published: Dec. 19, 2024

Progress in our knowledge of tumor regulatory mechanisms and complexity led to the understanding physical parameters cancer cells their microenvironment, including mechanical, thermal, electrical properties, solid stress, liquid pressure, as critical regulators progression potential prognostic markers associated with clinical outcomes. The biological hallmarks abnormalities tumors are mutually reinforced, promoting a vicious cycle progression. A comprehensive analysis is for developing more robust diagnostic improving treatment efficiency. Like traits, features characterized by inter- intratumoral heterogeneity. dynamic changes properties during result highlight necessity spatial temporal settings. This review focuses on basis tumor-specific state-of-the-art methods analyses, perspective translation. importance disease therapy resistance, well current strategies monitor target traits clinics, highlighted.

Language: Английский

Viscoelastic Mechanics of Living Cells DOI
Hui Zhou,

R. S. Liu,

Yizhou Xu

et al.

Physics of Life Reviews, Journal Year: 2025, Volume and Issue: 53, P. 91 - 116

Published: March 1, 2025

Language: Английский

Citations

0
Fascial Manual Medicine: A Continuous Evolution DOI Open Access
Bruno Bordoni, Allan R Escher

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 14, 2024

From the perspective of fascial manual medicine (FMM), body should not be considered as a set compartments, but functional continuum, where most tissues (considering embryology) are fascia. The cells that make up fascia can use multiple strategies to communicate, with neighboring cells, tissue which they belong, and entire body, thanks biochemical (microscopy) electromagnetic (nanoscopy) possibilities. These capacities send receive information border or layer different seem absent. All techniques profess only ones work on patient's symptoms, dictating standardized procedure all patients undergo, represent clinical deviation. Likewise, thinking approach provide biomechanical stimuli single specific structure is conceptual error. This narrative review briefly reviews history fascial-related nomenclature how system currently considered, posing new reflections continuum could conceived by practitioners who apply FMM in clinic, such osteopaths, chiropractors, physiotherapists.

Language: Английский

Citations

1
Heterogeneity of tumor biophysical properties and their potential role as prognostic markers DOI Creative Commons
Anja Madleine Markl,

Daniel Nieder,

Diana Isabel Sandoval-Bojorquez

et al.

Published: Dec. 19, 2024

Progress in our knowledge of tumor regulatory mechanisms and complexity led to the understanding physical parameters cancer cells their microenvironment, including mechanical, thermal, electrical properties, solid stress, liquid pressure, as critical regulators progression potential prognostic markers associated with clinical outcomes. The biological hallmarks abnormalities tumors are mutually reinforced, promoting a vicious cycle progression. A comprehensive analysis is for developing more robust diagnostic improving treatment efficiency. Like traits, features characterized by inter- intratumoral heterogeneity. dynamic changes properties during result highlight necessity spatial temporal settings. This review focuses on basis tumor-specific state-of-the-art methods analyses, perspective translation. importance disease therapy resistance, well current strategies monitor target traits clinics, highlighted.

Language: Английский

Citations

0