Green synthesis of ZnO, Fe 3 O 4 , and TiO 2 nanoparticles: exploring enhanced bacterial inhibition, catalysis, and photocatalysis for sustainable environmental applications DOI

M. S. Anandha Prabhu,

G. Edwin Sheela,

Hanan Alzahrani

et al.

International Journal of Environmental & Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 25

Published: Oct. 7, 2024

This study investigates the physicochemical and biological properties of metal oxide nanoparticles (TiO2, ZnO, Fe3O4) synthesised via phytosynthesis method using an extract from Boerhaavia diffusa leaves (BDL). The proteins phenols present in BDL played essential roles reducing stabilising TiO2, Fe3O4 nanoparticles. reveals size-dependent morphological, structural, characteristics produced FTIR spectra confirm involvement synthesis process Transmission electron microscopy (TEM) analysis TiO2 identified small, spherical particles (9 nm diameter). BDL-derived demonstrated significant photocatalytic activity, achieving degradation rates 98.96%, 96.26%, 94.42%, respectively, decomposition mono-azo dye after 40 minutes UV irradiation. reaction for were 0.367/min, 0.186/min, 0.061/min, when catalysing reduction 4-Nitrophenol (4-NP) to 4-Aminophenol NaBH4. exhibited antibacterial effectiveness, showing a 23.6 mm zone inhibition against Salmonella typhi. remarkable cytotoxicity lung cancer cell lines with IC50 values 76.36 µg/mL, 90.21 94.61 respectively. potential applications antibacterial, anticancer, catalytic, fields, contributing sustainable development multifunctional nanomaterials various technical environmental advancements.

Language: Английский

Effective killing of Mycobacterium abscessus biofilm by nanoemulsion delivery of plant phytochemicals DOI Creative Commons
Casey Albano, Ahmed Nabawy, Wyatt C. Tran

et al.

Microbiology Spectrum, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

ABSTRACT Mycobacterium is an acid-fast, aerobic, non-motile, and biofilm-forming bacterium. The increasing prevalence of mycobacterial infections makes it necessary to find new methods combat the resistance bacteria conventional antibiotics. abscessus emerging pathogen that intrinsically drug resistant due several factors, including impermeable cell envelope, efflux pumps, target-modifying enzymes, ability form thick, robust biofilms. Phytochemicals are promising antimicrobials; however, their poor solubility in water inability penetrate biofilms render them inefficient killing bacterial In this study, we demonstrate efficacy polymer-stabilized phytochemical nanoemulsions M. These improve stability phytochemicals enable biofilm penetration eradication. We show emulsions effectively eliminated vitro model killed non-replicating persister cells Wayne hypoxia model. were also effective vivo a wound infection findings potential as alternative antibiotics for treatment infections. IMPORTANCE among opportunistic pathogens cause nontuberculous diseases. caused by difficult treat because bacterium many currently available antibiotics, limiting chemotherapeutic strategies. Furthermore, forms clinically relevant settings, making treat. Many have potent antimicrobial activities, but hydrophobicity limits clinical applications. tested delivery strategy where hydrophobic plant emulsified with biodegradable nanosponge. emulsification such carvacrol eugenol more against further nanoemulsified can kill hypoxia-induced dormant skin mice. Our data pave way use nanosponge platform create synergy combining other antimycobacterial drugs.

Language: Английский

Citations

0
Surfactant Mediated Dispersion and stabilization of nano-emulsion droplets enhance antimicrobial activity against multidrug resistant bacteria DOI
Pallavi Shukla,

Priya Ranjan Prasad Verma,

Vinita Tiwari

et al.

Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: 426, P. 127300 - 127300

Published: March 6, 2025

Language: Английский

Citations

0
Current status and future applications of plant-derived essential oils DOI
Muhammad Naeem,

Umra Aqeel,

Sana

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 3 - 14

Published: Jan. 1, 2025

Language: Английский

Citations

0
Understanding colloidal behavior in açaí (Euterpe oleraceae)-based nanoemulsions DOI
M. A. J. F. Ferreira, Leandro Rocha, Rodrigo Alves Soares Cruz

et al.

PeerJ Organic Chemistry, Journal Year: 2025, Volume and Issue: 7, P. e13 - e13

Published: April 24, 2025

Background In recent years there has been growing interest in novel, eco-friendly, natural product-based colloids, including nutraceuticals and cosmetics. Despite the Amazon region’s globally recognized biodiversity, efforts to sustainably use products for viable applications remain at forefront of innovation. The superfruit Euterpe oleracea Mart, commonly known as açaí, is by its high level phenolic compounds valuable oil. However, best our knowledge, studies on colloidal chemistry combination oil with phenolic-rich extract are scarce. Therefore, aim this study was evaluate generation nanoemulsions containing açaí phytoglycerol through a low-energy method, investigating influence surfactant’s nature ratio droplet formation stabilization, enhancing potential sustainable product development. Methods Total phenolics açaí-based obtained from Heide Extratos Vegetais ® were quantified using Folin-Ciocalteau/Basf method. evaluated individual or blended non-ionic surfactants hydrophilic-lipophilic balance (HLB) values ranging 9 15. consisted 90% (w/w) aqueous phase (5% deionized water) 10% oily (varying ratios surfactants, 7:3 9:1). formulations monitored color, appearance, p signs instability. Additional systems then prepared twice amount phase, followed 1:1 dilution achieve same concentrations previously reported. optimal subjected dynamic light scattering analysis room temperature (25 °C) after linear ramp. Results spectrophotometric characterization revealed that contains 2.8 ± 0.4 mg/mL gallic acid equivalents. Various instability phenomena observed most surfactant-to-oil (SOR) different surfactants. suitable achieved polysorbate 85 (HLB 11) 80/sorbitan monooleate 13) an SOR 9:1. pair exhibited smaller sizes ( ca 200 nm) showed no statistically significant difference size during storage. slope versus also indicated nanoemulsion 9:1 more stable system solely 11).

Language: Английский

Citations

0
Lactobacillus-derived Exopolysaccharide Nanoemulsions for Essential Oils Delivery: Improving Bioaccessibility, Gastrointestinal Stability, and Prebiotic Function DOI
Sangeeta Balyan, V. S. Dadwal, Samikshya Bhattarai

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106891 - 106891

Published: May 1, 2025

Language: Английский

Citations

0
Pharmacology and therapeutic potential of agarwood and agarwood tree leaves in periodontitis DOI Creative Commons
Chen Xie,

Jing-Zhe Dong,

Bing-Shuai Lu

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 11, 2024

The main bioactive components of agarwood, derived from Aquilaria sinensis, include sesquiterpenes, 2-(2-phenethyl) chromone derivatives, aromatic compounds, and fatty acids, which typically exert anti-inflammatory, antioxidant, immune-modulating, hypoglycemic, antitumor pharmacological effects in the form essential oils. Agarwood tree leaves, rich flavonoids, flavonoid also exhibit significant immune-modulating effects. These properties are particularly relevant to treatment periodontitis, given that inflammatory responses, oxidative stress, immune dysregulation key pathological mechanisms disease, highlighting substantial potential agarwood leaves this therapeutic area. However, low solubility poor bioavailability oils present challenges necessitate development improved active formulations. In review, we will introduce components, extraction methods, actions, clinical applications analyzing its prospects for periodontitis.

Language: Английский

Citations

2
Translational perspectives on the therapeutic potential of Hyptis crenata essential oil terpenes in smooth muscle function DOI
André Nogueira Cardeal dos Santos, José Ednésio da Cruz Freire,

Bruna Ferreira Rodrigues

et al.

Planta Medica, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Monoterpenes and sesquiterpenes are classes of organic compounds found in various natural products, such as the essential oil

Language: Английский

Citations

1
Characterization and Determination of the Antibacterial Activity of Baccharis dracunculifolia Essential-Oil Nanoemulsions DOI Creative Commons

Erika da Silva Monteiro,

Franklyn Santos da Silva,

Karolina Oliveira Gomes

et al.

Antibiotics, Journal Year: 2023, Volume and Issue: 12(12), P. 1677 - 1677

Published: Nov. 29, 2023

The aim of this study was to evaluate the antibacterial activity nanoemulsions Baccharis dracunculifolia essential oil. volatile compounds oil were identified using gas chromatography-mass spectrometry. properties (droplet size, polydispersity index, pH, and electrical conductivity) determined. activities its evaluated MIC, MBC, disk diffusion. microorganisms used were: Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus 14579, Streptococcus mutans 25175, Enterococcus faecalis 29212) Gram-negative (Pseudomonas aeruginosa 27853, Klebsiella pneumoniae BAA-1706, Salmonella enterica 14028, Escherichia coli 25922). major B. limonene (19.36%), (E)-nerolidol (12.75%), bicyclogermacrene (10.76%), β-pinene (9.60%). had a mean droplet size between 13.14 56.84 nm. presented lower statistically significant MIC values compared oil, indicating enhancement bacteriostatic action. diffusion method showed that both inhibition zones only for bacteria, while there no results against has better antimicrobial effect on microorganisms.

Language: Английский

Citations

2
Vaccinium macrocarpon Based Fe-Doped Zno Nanoparticles as an Alternate Against Resistant Uropathogens DOI

Saiqa Sardar,

Atta Ur Rahman, Bakhtawar Khan

et al.

BioNanoScience, Journal Year: 2024, Volume and Issue: 14(3), P. 2649 - 2664

Published: Aug. 5, 2024

Language: Английский

Citations

0
Green synthesis of ZnO, Fe 3 O 4 , and TiO 2 nanoparticles: exploring enhanced bacterial inhibition, catalysis, and photocatalysis for sustainable environmental applications DOI

M. S. Anandha Prabhu,

G. Edwin Sheela,

Hanan Alzahrani

et al.

International Journal of Environmental & Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 25

Published: Oct. 7, 2024

This study investigates the physicochemical and biological properties of metal oxide nanoparticles (TiO2, ZnO, Fe3O4) synthesised via phytosynthesis method using an extract from Boerhaavia diffusa leaves (BDL). The proteins phenols present in BDL played essential roles reducing stabilising TiO2, Fe3O4 nanoparticles. reveals size-dependent morphological, structural, characteristics produced FTIR spectra confirm involvement synthesis process Transmission electron microscopy (TEM) analysis TiO2 identified small, spherical particles (9 nm diameter). BDL-derived demonstrated significant photocatalytic activity, achieving degradation rates 98.96%, 96.26%, 94.42%, respectively, decomposition mono-azo dye after 40 minutes UV irradiation. reaction for were 0.367/min, 0.186/min, 0.061/min, when catalysing reduction 4-Nitrophenol (4-NP) to 4-Aminophenol NaBH4. exhibited antibacterial effectiveness, showing a 23.6 mm zone inhibition against Salmonella typhi. remarkable cytotoxicity lung cancer cell lines with IC50 values 76.36 µg/mL, 90.21 94.61 respectively. potential applications antibacterial, anticancer, catalytic, fields, contributing sustainable development multifunctional nanomaterials various technical environmental advancements.

Language: Английский

Citations

0