A Macroscopic Exploration of the Ideoscape on Exosomes for Bone Regeneration DOI Creative Commons
Maria Teresa Colangelo,

Marco Meleti,

Stefano Guizzardi

et al.

Osteology, Journal Year: 2024, Volume and Issue: 4(4), P. 159 - 178

Published: Oct. 8, 2024

Background: Exosomes, nanoscale extracellular vesicles, play a crucial role in tissue physiology and regeneration. This study uses infometric techniques to explore the structure of exosome-based bone regeneration research. Methods: We applied BERTopic, an advanced topic modeling algorithm, comprehensive corpus scientific literature on exosomes regeneration, identifying key themes such as stem cell studies, healing, regenerative applications, with orthopedics dentistry emerging dominant subfields. To further investigate ‘ideoscape’, i.e., conceptual landscape that maps how ideas, methods, are interconnected across field, we extracted significant concepts from abstracts using GPT 3.5 turbo created knowledge graphs. Results: Our analysis revealed rapid growth field dental which has outpaced other topics by twofold. highlighted central periodontal cells their cellular processes—proliferation, migration, differentiation—along clinical applications. approach provided clear visualization field’s intellectual structure, showing interconnected. findings offer view evolving trends revealing not only most active research areas but also gaps opportunities for investigation. Conclusions: exemplifies utility combining graph creation map trends, offering flexible largely automated tool researchers vast bodies guide future directions.

Language: Английский

A Macroscopic Exploration of the Ideoscape on Exosomes for Bone Regeneration DOI Creative Commons
Maria Teresa Colangelo,

Marco Meleti,

Stefano Guizzardi

et al.

Osteology, Journal Year: 2024, Volume and Issue: 4(4), P. 159 - 178

Published: Oct. 8, 2024

Background: Exosomes, nanoscale extracellular vesicles, play a crucial role in tissue physiology and regeneration. This study uses infometric techniques to explore the structure of exosome-based bone regeneration research. Methods: We applied BERTopic, an advanced topic modeling algorithm, comprehensive corpus scientific literature on exosomes regeneration, identifying key themes such as stem cell studies, healing, regenerative applications, with orthopedics dentistry emerging dominant subfields. To further investigate ‘ideoscape’, i.e., conceptual landscape that maps how ideas, methods, are interconnected across field, we extracted significant concepts from abstracts using GPT 3.5 turbo created knowledge graphs. Results: Our analysis revealed rapid growth field dental which has outpaced other topics by twofold. highlighted central periodontal cells their cellular processes—proliferation, migration, differentiation—along clinical applications. approach provided clear visualization field’s intellectual structure, showing interconnected. findings offer view evolving trends revealing not only most active research areas but also gaps opportunities for investigation. Conclusions: exemplifies utility combining graph creation map trends, offering flexible largely automated tool researchers vast bodies guide future directions.

Language: Английский

Citations

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