Spectrum–effect relationship between HPLC fingerprint and hypoglycemic of litchi leaves (Litchi chinensis Sonn) in vitro DOI

Yanli Liang,

Jingjing Xie,

Dongfang Huang

et al.

Biomedical Chromatography, Journal Year: 2024, Volume and Issue: 38(9)

Published: July 8, 2024

Litchi chinensis Sonn (Litchi) has been listed in the Chinese Pharmacopeia, and is an economically medicinally valuable species within family Sapindaceae. However, material basis of its pharmacological action pharmacodynamic substances associated with hypoglycemic effect are still unclear. The predominant objective this study was to establish fingerprint profile litchi leaves evaluate relationship between components high-performance liquid chromatography (HPLC) leaves, assess by measuring α-glucosidase α-amylase inhibition, find spectrum-effect bivariate correlation analysis, Grey relational analysis partial least squares regression analysis. In study, established HPLC, a total 15 common peaks were identified that clearly calibrated eight components, P1 being gallic acid, P2 protocatechuic P3 catechin, P6 epicatechin, P12 rutin, P13 astragalin, P14 quercetin P15 kaempferol. similarities fingerprints 11 batches 0.766-0.979. Simultaneously, results showed chemical constituents represented P8, P3, P12, P14, P2, P13, P11 relevant effect.

Language: Английский

Spectrum-effect relationship of the cardiovascular-protective effect of with Chrysanthemi Flos by UPLC-MS/MS and component knock-out method DOI

Ranran Cheng,

Cheng Xiang,

Dongliang Jiang

et al.

Food and Chemical Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 115372 - 115372

Published: March 1, 2025

Language: Английский

Citations

0
Spectrum–effect relationship between HPLC fingerprint and hypoglycemic of litchi leaves (Litchi chinensis Sonn) in vitro DOI

Yanli Liang,

Jingjing Xie,

Dongfang Huang

et al.

Biomedical Chromatography, Journal Year: 2024, Volume and Issue: 38(9)

Published: July 8, 2024

Litchi chinensis Sonn (Litchi) has been listed in the Chinese Pharmacopeia, and is an economically medicinally valuable species within family Sapindaceae. However, material basis of its pharmacological action pharmacodynamic substances associated with hypoglycemic effect are still unclear. The predominant objective this study was to establish fingerprint profile litchi leaves evaluate relationship between components high-performance liquid chromatography (HPLC) leaves, assess by measuring α-glucosidase α-amylase inhibition, find spectrum-effect bivariate correlation analysis, Grey relational analysis partial least squares regression analysis. In study, established HPLC, a total 15 common peaks were identified that clearly calibrated eight components, P1 being gallic acid, P2 protocatechuic P3 catechin, P6 epicatechin, P12 rutin, P13 astragalin, P14 quercetin P15 kaempferol. similarities fingerprints 11 batches 0.766-0.979. Simultaneously, results showed chemical constituents represented P8, P3, P12, P14, P2, P13, P11 relevant effect.

Language: Английский

Citations

1