Pharmacokinetics of N‐acetyl‐l‐cysteine in chickens DOI
Albena Roydeva,

Gabriela Beleva,

Daniel Gadzhakov

et al.

Journal of Veterinary Pharmacology and Therapeutics, Journal Year: 2024, Volume and Issue: 47(5), P. 403 - 415

Published: May 15, 2024

N-acetyl-l-cysteine (NAC) has been suggested as an antioxidant that can alleviate the negative effects of stress conditions in broilers. However, knowledge its pharmacokinetics (PK) this avian species is very limited. Therefore, study aimed to shed more light on PK properties NAC chickens. Broilers were subjected single intravenous (i.v.) or oral (p.o.) treatment multiple administrations via feed. Drug concentrations determined by LC-MS/MS, and data non-compartmental analysis modeled non-linear mixed effect approach. was eliminated a short time after i.v. treatment, with t

Language: Английский

Target-triggered dual suppression of self-enhanced ECL sensor for sensitive detection of L-Cysteine DOI

Xuemei Pi,

Rong Wang, Y. Jay Guo

et al.

Talanta, Journal Year: 2025, Volume and Issue: 294, P. 128216 - 128216

Published: April 25, 2025

Language: Английский

Citations

0
Pharmacokinetics of N‐acetyl‐l‐cysteine in chickens DOI
Albena Roydeva,

Gabriela Beleva,

Daniel Gadzhakov

et al.

Journal of Veterinary Pharmacology and Therapeutics, Journal Year: 2024, Volume and Issue: 47(5), P. 403 - 415

Published: May 15, 2024

N-acetyl-l-cysteine (NAC) has been suggested as an antioxidant that can alleviate the negative effects of stress conditions in broilers. However, knowledge its pharmacokinetics (PK) this avian species is very limited. Therefore, study aimed to shed more light on PK properties NAC chickens. Broilers were subjected single intravenous (i.v.) or oral (p.o.) treatment multiple administrations via feed. Drug concentrations determined by LC-MS/MS, and data non-compartmental analysis modeled non-linear mixed effect approach. was eliminated a short time after i.v. treatment, with t

Language: Английский

Citations

1