Long-term
inflammation
and
persistent
bacterial
infection
are
primary
contributors
to
unhealed
chronic
wounds.
The
use
of
conventional
antibiotics
often
leads
bacteria
drug
resistance,
diminishing
wound
healing
effectiveness.
Nanozymes
have
become
a
promising
alternative
antimicrobial
materials
due
their
low
cost,
easy
synthesis,
good
stability.
Herein,
we
develop
novel
sprayable
hydrogel
based
on
carboxymethyl
chitosan
(CMCS)
oxidized
hyaluronic
acid
(OHA),
incorporating
Au
nanoparticle-carbon
nitride
(AuNPs-C3N4)
nanozyme,
glucose,
Mn2+
for
bacteria-infected
healing.
forms
rapidly
in
situ
upon
spraying
gradually
degrades
the
area,
releasing
AuNPs-C3N4
which
exhibits
robust
glucose
oxidase-like
(GOx-like)
activity,
initiating
comprehensive
catalytic
cascade
through
Mn2+-mediated
Fenton-like
reaction
that
generates
hydroxyl
radicals
(•OH)
eliminate
Staphylococcus
aureus
(S.
aureus)
Methicillin-resistant
S.
(MRSA).
Computational
results
indicate
interactions
between
AuNPs
g-C3N4
maximize
synergistic
effects
heterojunction,
improving
O2
adsorption
facilitating
electron-O2
optimize
activity.
Further
experiments
demonstrate
can
cover
wounds
situ,
while
CMCS
promotes
collagen
production
fibroblast
proliferation,
offering
viable
strategy
Nano Materials Science,
Journal Year:
2023,
Volume and Issue:
6(2), P. 115 - 138
Published: Sept. 11, 2023
Energy
storage
and
conservation
are
receiving
increased
attention
due
to
rising
global
energy
demands.
Therefore,
the
development
of
materials
is
crucial.
Thermal
(TES)
systems
based
on
phase
change
(PCMs)
have
in
prominence
over
past
two
decades,
not
only
because
their
outstanding
heat
capacities
but
also
superior
thermal
regulation
capability.
However,
issues
such
as
leakage
low
conductivity
limit
applicability
a
variety
settings.
Carbon-based
graphene
its
derivatives
can
be
utilized
surmount
these
obstacles.
This
study
examines
recent
advancements
graphene-based
composites
(PCCs),
where
nanostructures
graphene,
oxide
(GO),
functionalized
graphene/GO,
aerogel
(GA)
incorporated
into
PCMs
substantially
enhance
shape
stability
that
could
translated
better
capacity,
durability,
temperature
response,
thus
boosting
attractiveness
for
TES
systems.
In
addition,
applications
PCCs
various
disciplines,
buildings,
solar
utilization,
battery
management,
discussed
summarized.
Small,
Journal Year:
2024,
Volume and Issue:
20(30)
Published: March 7, 2024
Abstract
In
recent
years,
there
has
been
growing
interest
in
developing
innovative
materials
and
therapeutic
strategies
to
enhance
wound
healing
outcomes,
especially
for
chronic
wounds
antimicrobial
resistance.
Metal–organic
frameworks
(MOFs)
represent
a
promising
class
of
next‐generation
dressings.
Their
high
surface
area,
pore
structures,
stimuli‐responsiveness,
antibacterial
properties,
biocompatibility,
potential
combination
therapies
make
them
suitable
complex
care
challenges.
MOF‐based
composites
promote
cell
proliferation,
angiogenesis,
matrix
synthesis,
acting
as
carriers
bioactive
molecules
promoting
tissue
regeneration.
They
also
have
stimuli‐responsivity,
enabling
photothermal
skin
cancer
infections.
Herein,
critical
analysis
the
current
state
research
on
MOFs
dressings
is
provided,
offering
valuable
insights
into
applications,
challenges,
future
directions
this
field.
This
literature
review
targeted
multifunctionality
nature
wound‐disease
therapy
from
different
aspects
discussed
most
advancements
made
context,
reader
will
find
how
contributed
field
yield
more
effective,
functional,
they
lead
next
generation
biomaterials
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(22)
Published: May 9, 2024
Hydrogels
have
emerged
as
promising
candidates
for
biomedical
applications,
especially
in
the
field
of
antibacterial
therapeutics,
due
to
their
unique
structural
properties,
highly
tunable
physicochemical
and
excellent
biocompatibility.
The
integration
stimuli-responsive
functions
into
hydrogels
holds
potential
enhance
properties
therapeutic
efficacy,
dynamically
responding
different
external
or
internal
stimuli,
such
pH,
temperature,
enzymes,
light.
Therefore,
this
review
describes
applications
hydrogel
dressings
responsive
stimuli
therapy.
collaborative
interaction
between
materials
is
discussed.
This
synergistic
approach,
contrast
conventional
materials,
not
only
amplifies
effect
but
also
alleviates
adverse
side
effects
diminishes
incidence
multiple
infections
drug
resistance.
provides
a
comprehensive
overview
current
challenges
outlines
future
research
directions
hydrogels.
It
underscores
imperative
ongoing
interdisciplinary
aimed
at
unraveling
mechanisms
wound
healing.
understanding
crucial
optimizing
design
implementation
Ultimately,
aims
offer
scientific
guidance
development
practical
clinical
application
dressings.
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(3), P. 300 - 300
Published: Feb. 21, 2024
Wounds,
which
are
becoming
more
common
as
a
result
of
traumas,
surgery,
burns,
and
chronic
illnesses
like
diabetes,
remain
critical
medical
problem.
Infectious
bacteria
impact
the
healing
process,
particularly
if
its
biofilm
(biological
films)
leads
to
prolonged
effect.
Nanomaterials
have
emerged
promising
candidates
in
field
wound
due
their
unique
properties
versatile
applications.
New
insights
into
interactions
between
nanomaterials
microenvironments
shed
light
on
mechanisms
underlying
therapeutic
effects.
However,
significantly
minimal
amount
research
has
been
carried
out
see
these
promote
process.
In
this
review,
we
provided
an
outline
various
types
that
studied
for
wounds
infection
prevention.
Overall,
utilization
holds
great
promise
continues
evolve,
providing
new
opportunities
development
effective
efficient
care
therapies.
Small,
Journal Year:
2024,
Volume and Issue:
20(23)
Published: Jan. 8, 2024
Abstract
Foreign
body
reaction
(FBR)
is
a
prevalent
yet
often
overlooked
pathological
phenomenon,
particularly
within
the
field
of
biomedical
implantation.
The
presence
FBR
poses
heavy
burden
on
both
medical
and
socioeconomic
systems.
This
review
seeks
to
elucidate
protein
“fingerprint”
implant
materials,
which
generated
by
physiochemical
properties
materials
themselves.
In
this
review,
activity
macrophages,
formation
foreign
giant
cells
(FBGCs),
development
fibrosis
capsules
in
context
are
introduced.
Additionally,
relationship
between
various
elucidated
detail,
as
an
overview
existing
approaches
technologies
employed
alleviate
FBR.
Finally,
significance
components
(metallic
non‐metallic
materials),
surface
CHEMISTRY
(charge
wettability),
physical
characteristics
(topography,
roughness,
stiffness)
establishing
also
well
documented.
conclusion,
aims
emphasize
importance
provides
current
perspectives
developing
with
anti‐FBR
properties.
Journal of Materials Chemistry B,
Journal Year:
2024,
Volume and Issue:
12(33), P. 7977 - 8006
Published: Jan. 1, 2024
The
objective
of
this
review
is
to
provide
an
up-to-date
and
all-encompassing
account
the
recent
advancements
in
domain
interactive
wound
dressings.
Considering
gap
between
achieved
desired
clinical
outcomes
with
currently
available
or
under-study
healing
therapies,
newer
more
specific
options
based
on
type
phase
are
reviewed.
Starting
from
comprehensive
description
process,
a
detailed
classification
dressings
presented.
Subsequently,
we
present
elaborate
significant
discussion
describing
(unconventional)
Latter
includes
biopolymer-based,
bioactive-containing
biosensor-based
smart
dressings,
which
discussed
separate
sections
together
their
applications
limitations.
Moreover,
(2-5
years)
trials,
patents
unconventional
marketed
products,
other
information
advanced
care
designs
techniques
discussed.
future
research
direction
highlighted,
peptides,
proteins,
human
amniotic
membranes
as
potential
Finally,
conclude
that
field
needs
further
development
offers
scope
for
integrating
process
technologies.
