Nigerian Journal of Pure and Applied Sciences, Journal Year: 2024, Volume and Issue: unknown, P. 5112 - 5131

Published: Dec. 4, 2024

Myrianthus arboreus stem bark is used as an anti-anxiety and pain reliever in traditional medicines. However, scanty scientific reports are available to corroborate these ethnomedicinal claims. Hence, this study investigated the anxiolytic peripheral analgesic potentials of methanol extract fractions mice. The potential was evaluated using elevated plus maze while effect mouse model acetic acid induced writhing test. Fourier-transform infrared analysis dichloromethane fraction also carried out. (125-500 mg/kg), aqueous at 250 mg/kg significantly (p<0.05) reduced anxiety indices mice compared control, consistent with effect. crude all number abdominal constrictions elicited by potentials. showed several functional groups fraction. hydroxyl functionality may be integral part some phenolic compounds such flavonoid tannins. This concluded that possess secondary plant metabolites responsible for its

Language: Английский