Persistent Poverty and Pediatric Cancer Survival DOI
Emma Hymel, Josiane Kabayundo, Krishtee Napit

et al.

PEDIATRICS, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

BACKGROUND Cancer is the leading cause of death by disease among US children. While previous studies have examined impact poverty on pediatric cancer outcomes, most relied single time point measures, which may not capture long-term, systemic effects poverty. Persistent poverty, defined as having 20% or more an area’s population below level for 30 years, represents a comprehensive measure sustained socioeconomic disadvantage. METHODS In this population-based study, we used Surveillance, Epidemiology, and End Results (SEER)-22 Registries Incidence Data with Census Tract Attributes Database data. Primary cases diagnosed children from 2006 to 2020 were included. Cox proportional hazards models compute association between persistent (1) early mortality (death within 3 months diagnosis) (2) overall cancer-specific mortality. RESULTS total, 97 132 included in our study; 12.63% resided persistent-poverty neighborhood at diagnosis. adjusted models, living was associated higher risk (adjusted hazard ratio [aHR], 1.26; 95% CI, 1.10–1.45) (aHR, 1.15; 1.10–1.21). survival leukemias 1.20; 1.09–1.31), central nervous system tumors 1.14; 1.04–1.26), hepatic 1.37; 1.01–1.85). CONCLUSIONS Our study observed increased neighborhoods. Continued investment research are critical developing effective strategies that reduce disparities improve outcomes patients affected

Language: Английский

Persistent Poverty and Pediatric Cancer Survival DOI
Emma Hymel, Josiane Kabayundo, Krishtee Napit

et al.

PEDIATRICS, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

BACKGROUND Cancer is the leading cause of death by disease among US children. While previous studies have examined impact poverty on pediatric cancer outcomes, most relied single time point measures, which may not capture long-term, systemic effects poverty. Persistent poverty, defined as having 20% or more an area’s population below level for 30 years, represents a comprehensive measure sustained socioeconomic disadvantage. METHODS In this population-based study, we used Surveillance, Epidemiology, and End Results (SEER)-22 Registries Incidence Data with Census Tract Attributes Database data. Primary cases diagnosed children from 2006 to 2020 were included. Cox proportional hazards models compute association between persistent (1) early mortality (death within 3 months diagnosis) (2) overall cancer-specific mortality. RESULTS total, 97 132 included in our study; 12.63% resided persistent-poverty neighborhood at diagnosis. adjusted models, living was associated higher risk (adjusted hazard ratio [aHR], 1.26; 95% CI, 1.10–1.45) (aHR, 1.15; 1.10–1.21). survival leukemias 1.20; 1.09–1.31), central nervous system tumors 1.14; 1.04–1.26), hepatic 1.37; 1.01–1.85). CONCLUSIONS Our study observed increased neighborhoods. Continued investment research are critical developing effective strategies that reduce disparities improve outcomes patients affected

Language: Английский

Citations

0