Lower Functional Status, Higher Comorbidity Burden, and Higher Levels of Stress Are Associated With Worse Joint Evening Fatigue and Depressive Symptom Profiles in Outpatients Receiving Chemotherapy DOI Creative Commons
Carolyn Harris, Bruce A. Cooper, Kate Oppegaard

et al.

European Journal of Cancer Care, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Significance: Evening fatigue and depressive symptoms are associated with several negative outcomes for patients cancer. However, the contribution of BOTH to patient remains unknown. This study identified subgroups distinct joint evening AND symptom profiles evaluated differences in demographic clinical characteristics, levels stress (i.e., global, cancer‐specific, cumulative life) resilience, severity common symptoms. Methods: Outpatients ( n = 1334) completed Lee Fatigue Scale Center Epidemiological Studies‐Depression scale six times over two cycles chemotherapy. Demographic other were assessed at enrollment. Joint using latent profile analysis. Profile parametric nonparametric tests. Results: Five Low Depression [Both Low: 20.0%], Moderate [Moderate Depression: 39.3%], Increasing Decreasing Increasing–Decreasing: 5.3%], Moderate: 27.6%], High High: 7.8%]). Compared Both classes, classes less likely be married, more report depression, had a lower functional status, worse comorbidity profile. higher life resilience. Conclusions: Multiple risk factors during chemotherapy identified, including burden, stress. These may used identify greatest poorer prescribe interventions decrease these

Language: Английский

Lower Functional Status, Higher Comorbidity Burden, and Higher Levels of Stress Are Associated With Worse Joint Evening Fatigue and Depressive Symptom Profiles in Outpatients Receiving Chemotherapy DOI Creative Commons
Carolyn Harris, Bruce A. Cooper, Kate Oppegaard

et al.

European Journal of Cancer Care, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Significance: Evening fatigue and depressive symptoms are associated with several negative outcomes for patients cancer. However, the contribution of BOTH to patient remains unknown. This study identified subgroups distinct joint evening AND symptom profiles evaluated differences in demographic clinical characteristics, levels stress (i.e., global, cancer‐specific, cumulative life) resilience, severity common symptoms. Methods: Outpatients ( n = 1334) completed Lee Fatigue Scale Center Epidemiological Studies‐Depression scale six times over two cycles chemotherapy. Demographic other were assessed at enrollment. Joint using latent profile analysis. Profile parametric nonparametric tests. Results: Five Low Depression [Both Low: 20.0%], Moderate [Moderate Depression: 39.3%], Increasing Decreasing Increasing–Decreasing: 5.3%], Moderate: 27.6%], High High: 7.8%]). Compared Both classes, classes less likely be married, more report depression, had a lower functional status, worse comorbidity profile. higher life resilience. Conclusions: Multiple risk factors during chemotherapy identified, including burden, stress. These may used identify greatest poorer prescribe interventions decrease these

Language: Английский

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